Results 51 to 60 of about 2,277,679 (245)

Testicular tumour, could it be benign? A clinical conundrum

, 2019
Testicular vasculitis (TV) is a cause of testicular infarction (TI) which can lead to significant morbidity and rarely mortality. Polyarteritis Nodosa (PAN) is the most common vasculitis that leads to testicular infarction (TI).
Desai, Devang, Wood, Dale, Chua, Dorothy, Shepherd, Benjamin   +3 more
core   +2 more sources

Codesign and Launch of ‘On the Ball’: An Inclusive Community‐Based ‘Testicular Awareness’ Campaign

Health Expectations
Introduction Increased awareness of testicular diseases can lead to early diagnosis. Evidence suggests that men's awareness of testicular diseases is low, with many expressing their willingness to delay help‐seeking for symptoms of concern.
Mohamad M. Saab, Varsha N. Shetty, Megan McCarthy, Martin P. Davoren, Angela Flynn, Ann Kirby, Steve Robertson, Gillian W. Shorter, David Murphy, Michael J. Rovito, Frances Shiely, Josephine Hegarty   +11 more
doaj   +1 more source

Ebselen alleviates testicular pathology in mice with Zika virus infection and prevents its sexual transmission. [PDF]

PLoS Pathogens, 2018
Despite the low case fatality, Zika virus (ZIKV) infection has been associated with microcephaly in infants and Guillain-Barré syndrome. Antiviral and vaccine developments against ZIKV are still ongoing; therefore, in the meantime, preventing the disease
Yogy Simanjuntak, Jian-Jong Liang, Si-Yu Chen, Jin-Kun Li, Yi-Ling Lee, Han-Chung Wu, Yi-Ling Lin   +6 more
doaj   +1 more source

SOX30 Facilitates Triple‐Negative Breast Cancer Metastasis via TNFR2–NF‐κB Signaling and Tumor Microenvironment Remodeling

Advanced Science, EarlyView.
SOX30 drives triple‐negative breast cancer (TNBC) metastasis through a dual mechanism: direct activation of the TNFR2/NF‐κB signaling cascade and subsequent CCL20‐mediated recruitment of tumor‐associated macrophages (TAMs) into the tumor microenvironment.
Pingping Gao, Na Sun, Ning Yang, Tingting Zhao, Rui Fu, Zhenyu Wu, Yuqin Zhou, Xuanni Tan, Yi Zhang, Fei Han, Xiaowei Qi   +10 more
wiley   +1 more source

Epigenetic: a molecular link between testicular cancer and environmental exposures?

Frontiers in Endocrinology, 2012
In the last decades, studies in rodents have highlighted links between in utero and/or neonatal exposures to molecules that alter endocrine functions and the development of genital tract abnormalities, such as cryptorchidism, hypospadias, and impaired ...
Aurelie eVega, Marine eBaptissart, Françoise eCaira, Florence eBrugnon, Jean-Marc A Lobaccaro, David H VOLLE   +5 more
doaj   +1 more source

DUET‐seq: An Open‐Source Droplet Platform for High‐Fidelity Joint Chromatin and Transcriptome Profiling Reveals Temporal Regulatory Decoupling in Single Cells

Advanced Science, EarlyView.
DUET‐seq is an open‐source droplet platform that jointly profiles chromatin accessibility and gene expression from the same nucleus. Dissolvable dual‐linker hydrogel beads and a one‐step intra‐droplet RT‐PCR co‐index both modalities in under 12 h at roughly $0.04 per cell.
Dong Cheng, Zijun Meng, Lan Wei, Pingjing Yang, Fanfan Zhang, Zhiyi Luo, Ting Lai, Chunli Li, Mengyao Zhao, Mengqin Xu, Jiaqi Wang, Linjun Li, Huarong Chen, Jin Li, Ailong Huang, Youquan Bu, Liuyang Zhao   +16 more
wiley   +1 more source

Clinical evaluation of testicular torsion presenting with acute abdominal pain in young males

Asian Journal of Urology, 2019
Objective: To evaluate the features of testicular torsion presenting with acute abdominal pain and to raise awareness of testicular torsion with specific symptoms.
Fujun Wang, Zengnan Mo
doaj   +1 more source

Inguinal and Scrotal Diseases in Children and Adolescents

대한영상의학회지, 2022
In children and adolescents, inguinal and scrotal diseases are relatively common, and imaging is very useful for the diagnosis and differential diagnosis of these diseases. Therefore, it is important to understand the imaging findings of these diseases.
Jaeyoung Lee, Youngtong Kim, Sungshick Jou, Chanho Park
doaj   +1 more source

WFS1 Deficiency Impairs PIAS4‐Associated SUMOylation and Increases Ubiquitin‐Mediated Spermatogenesis‐Related Protein Degradation Leading to Testicular Male Infertility

Advanced Science, EarlyView.
The findings establish a critical role for WFS1 in human male fertility. Mechanistically, WFS1 interacts with PIAS4 to promote the SUMOylation of key spermatogenesis‐associated proteins, which in turn competitively inhibits their K48‐linked ubiquitin‐mediated degradation during spermatogenesis.
Yunchuan Tian, Guicheng Zhao, Xiang Wang, Xinyao Tang, Gan Shen, Tiechao Ruan, Chuan Jiang, Shikun Zhao, Jincheng Zhang, Xinyue Cui, Liangchai Zhuo, Jun Ma, Yihong Yang, Tingting Lin, Ying Shen   +14 more
wiley   +1 more source