Results 31 to 40 of about 2,277,679 (245)

Testicular complications in connective tissue disease [PDF]

Archives of Disease in Childhood, 1981
Acute testicular symptoms are described in 2 patients with Schonlein-Henoch syndrome and in 1 with juvenile rheumatoid arthritis. The literature on testicular involvement in connective tissue disease of childhood is reviewed.
openaire   +2 more sources

CDKN2AIP-induced cell senescence and apoptosis of testicular seminoma are associated with CARM1 and eIF4β

Acta Biochimica et Biophysica Sinica, 2022
Testicular seminoma is a relatively rare tumor which is mostly detected in male population aged from 15 to 35 years old. Although several molecular biomarkers have been identified to be associated with testicular seminoma pathogenesis, the exact ...
Cao Yuming, Chen Zhenlie, Qin Zihan, Qian Kaiyu, Liu Tongzu, Zhang Yuanzhen   +5 more
doaj   +1 more source

In utero exposure to di(n-butyl) phthalate and testicular dysgenesis:comparison of fetal and adult end points and their dose sensitivity [PDF]

, 2007
BACKGROUND: Fetal exposure of male rats to di(n-butyl) phthalate (DBP) induces reproductive disorders similar to those in human testicular dysgenesis syndrome (TDS), including infertility, cryptorchidism, focal "dysgenetic areas," and Sertoli cell-only ...
Mahood, I. Kim, Scott, Hayley M., Hayley M. Scott, Richard M. Sharpe, I. Kim Mahood, Nina Hallmark, Walker, Marion, Sharpe, Richard M., Hallmark, Nina, Richard Brown, Brown, Richard, Marion Walker   +11 more
core   +1 more source

A scoping review of imatinib-induced testicular toxicity and male fertility impairment

Frontiers in Endocrinology
BackgroundImatinib, the first-generation tyrosine kinase inhibitor (TKI), has been widely adopted as frontline therapy for chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GIST). Growing evidence indicates potential gonadotoxic effects,
Xia Ji, Xia Ji, Mohd Faizal Ahmad, Mohd Helmy Mokhtar, XiaoYing He, Abdul Kadir Abdul Karim   +5 more
doaj   +1 more source

Promoting men’s awareness, self-examination, and help-seeking for testicular disorders: a systematic review of interventions [version 3; peer review: 2 approved]

HRB Open Research, 2023
Background: Testicular cancer (TC) is among the most commonly diagnosed cancers in men aged 15–40 years. The incidence of TC is on the rise. Benign testicular disorders, such as testicular torsion and epididymitis, can lead to testicular ischemia, sepsis,
Mohamad M. Saab, Aileen Murphy, Martin P. Davoren, Eoghan Cooke, David Murphy, Serena Fitzgerald, Margaret Landers, Michael J. Rovito, Noel Richardson, Mike Murphy, Christian Von Wagner, Josephine Hegarty, Darren Dahly   +12 more
doaj   +1 more source

Promoting ‘testicular awareness’: Co‐design of an inclusive campaign using the World Café Methodology

Health Expectations
Introduction Testicular cancer is the most common cancer in men aged 15–44 years in many countries. Most men with testicular cancer present with a lump. Testicular symptoms are more likely to occur secondary to benign diseases like epididymo‐orchitis, a ...
Mohamad M. Saab, Varsha N. Shetty, Megan McCarthy, Martin P. Davoren, Angela Flynn, Ann Kirby, Steve Robertson, Gillian W. Shorter, David Murphy, Michael J. Rovito, Frances Shiely, Josephine Hegarty   +11 more
doaj   +1 more source

Testicular Glycogen Metabolism: An Overlooked Source of Energy for Spermatogenesis?

BioChem, 2022
The incidence of male infertility has been increasing over the years and is now becoming a serious health problem. This trend has been followed by an increase in metabolic diseases, which are known to induce clear alterations in testicular metabolism ...
Ricardo Silva, David F. Carrageta, Marco G. Alves, Pedro F. Oliveira   +3 more
doaj   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Filarial granuloma of the testicular tunic mimicking a testicular neoplasm: a case report

Journal of Medical Case Reports, 2008
Introduction Any firm or solid intratesticular mass on examination and/or any hypoechoic area within the tunica albuginea on imaging is markedly suspicious for testicular cancer.
Barreto Savio G, Rodrigues Jude, Pinto Roque GW   +2 more
doaj   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source