Results 41 to 50 of about 2,220,072 (197)

Ochratoxin A: In Utero Exposure in Mice Induces Adducts in Testicular DNA [PDF]

, 2010
Ochratoxin A (OTA) is a nephrotoxin and carcinogen that is associated with Balkan endemic nephropathy and urinary tract tumors. OTA crosses the placenta and causes adducts in the liver and kidney DNA of newborns.
Jennings-Gee, Jamie E., Mark Steven Miller, Tozlovanu, Mariana, Jamie E. Jennings-Gee, Mariana Tozlovanu, Miller, Mark Steven, Annie Pfohl-Leszkowicz, Gary G. Schwartz, Schwartz, Gary G., Manderville, Richard A., Pfohl-Leszkowicz, Annie, Richard Manderville   +11 more
core   +1 more source

Molecular genetics and pathophysiology of 17 beta-hydroxysteroid dehydrogenase 3 deficiency. [PDF]

, 1996
Autosomal recessive mutations in the 17 beta-hydroxysteroid dehydrogenase 3 gene impair the formation of testosterone in the fetal testis and give rise to genetic males with female external genitalia.
Blethen, Sandra L., Geissler, Wayne M., Mendonca, Berenice B., Schwarz, Hans P., Russell, David D., Bloise, Walter, Grumbach, Melvin M., Davis, Daphne L., Andersson, Stefan, New, Maria I., Wu, Ling, Witchel, Selma F., Griffin, James E., Cutler Jr., Gordon B., Wilson, Jean D.   +14 more
core   +1 more source

Testicular cancer and Hodgkin disease in the same patient [PDF]

Cancer, 1993
Although testicular cancer and Hodgkin disease are the neoplasms with the highest incidence in young men, only 13 cases of metachronous and 2 cases of synchronous occurrence in the same person were reported before 1991.A 30-year-old man is described, in whom, 2 years after radiation therapy for Stage IIIA Hodgkin disease, a testicular nonseminomatous ...
A, Gerl, C, Clemm, C, Salat, J, Mittermüller, W, Bomfleur, W, Wilmanns   +5 more
openaire   +2 more sources

Runs of homozygosity and testicular cancer risk [PDF]

, 2019
Background: Testicular germ cell tumour (TGCT) is highly heritable but > 50% of the genetic risk remains unexplained. Epidemiological observation of greater relative risk to brothers of men with TGCT compared to sons has long alluded to recessively ...
West, C, Townsend, P. A., Loveday, C, Park, J. Y., Litchfield, K, Ingles, SA, Srihari, N. N., Beesley, S., Welch, R, Lu, Y. J., Albanes, D, Dunning, A. M., Cybulski, C., Neuhausen, SL, Bloomfield, D., Douglas, F., Stockdale, A, West, C., Huddart, R. A., Baybrooke, J, Douglas, F, Muir, K, Askill, C., Albanes, D., Benlloch, S, Brown, R, Kogevinas, M, Newcomb, LF, Broderick, P, Haiman, C. A., Al Olama, A. A., Appel, W, Benlloch, S., Lessel, D., Hamdy, FC, Stanford, JL, Batra, J., John, EM, Sud, A., Cannon-Albrigh, L., Donovan, JL, Hong, A, Sreenivasan, T, Madhavan, K, Mazhar, D., Winkler, M., Sarwar, N., Teixeira, M. R., Hennig, I, Brown, R., Money-Kryle, J., Stuart, N, Bertelli, G., Batra, J, Joffe, J., White, J, Faust, G., Mehra, R, Rogers, P, Schleutker, J, Faust, G, Lamont, A, De Ruyck, K, Tangen, CM, Maier, C., Menegaux, F., Dunning, AM, Chakraborti, P., Claessens, F., Pandha, H., Easton, DF, Rustin, G., Kim, J., Kaneva, R., Khaw, K-T, Howard, G., Hamilton, R. J., Clements, J, Usmani, N, Sorensen, KD, Orr, N., Sreenivasan, T., Hatton, M., Gilby, E., Gale, J., Stuart, N., Rosenstein, B. S., Giles, G. G., Highley, M, Holroyd, A, Kibel, AS, Holroyd, A., Dudakia, D, Cybulski, C, Wiklund, F., Lessel, D, Schumacher, F. R., Barber, J., Howard, G, Gronberg, H, Cannon-Albrigh, L, Huddart, RA, Madhavan, K., Wolk, A, Rathmell, A, Mucci, L., Eeles, R., Stevens, VL, Hrounda, D, Neal, DE, Dominguez, MG, Kogevinas, M., Razack, A, Cole, D., Levy, M, Money-Kryle, J, Park, JY, Pathak, S, Hamid, A, Hamilton, RJ, Travis, R. C., Leahy, M, Wolk, A., Peto, J, Henderson, B. E., Srihari, NN, Brock, C, Henderson, BE, Koutros, S, Baybrooke, J., Chowdhury, S., Penney, K. L., Mucci, L, Woby, S, Razack, A., Stanford, J. L., Easton, D. F., Kote-Jarai, Z., Gale, J, Donovan, J. L., Butt, M., Mehra, R., Claessens, F, Giles, GG, Kaneva, R, Seckl, M, Haiman, CA, Maehle, L, Teixeira, MR, Al Olama, AA, Simmonds, P, Neal, D. E., Savage, P., Cancel-Tassin, G, Houlston, RS, McAteer, J, Broderick, P., Nordestgaard, BG, Pashayan, N, Schumacher, FR, Woby, S., Brenner, H., Wiklund, F, Rathmell, A., Menegaux, F, Hennig, I., Roobol, MJ, Hong, A., Brock, C., Dudakia, D., Khaw, K. T., Hatton, M, Clements, J., Kibel, A. S., Turnbull, C., Humber, C., Vega, A, Eeles, R, Schleutker, J., Sorensen, K. D., Muir, K., Gapster, S., Berndt, S. I., Rogers, P., Bertelli, G, Barber, J, Orr, N, Lamont, A., Cancel-Tassin, G., Stockdale, A., John, E. M., Humber, C, Appel, W., Usmani, N., Stevens, V. L., Conti, D. V., Neuhausen, S. L., Travis, RC, Kelly, K., Newcomb, L. F., Mazhar, D, Koutros, S., Bloomfield, D, Clark, P, Chanock, S, Maier, C, Hamdy, F. C., Askill, C, Chanock, S., Gronberg, H., Sarwar, N, Beesley, S, Kote-Jarai, Z, Brenner, H, Reid, A., Conti, DV, Ruyck, K., Winkler, M, Hrounda, D., Tangen, C. M., Rustin, G, Litchfield, K., Chowdhury, S, Lu, Y-J, Clark, P., Gapster, S, Sud, A, Ingles, S. A., Pathak, S., Thibodeau, SN, Kim, J, Roobol, M. J., Maehle, L., Pandha, H, Peto, J., Highley, M., Savage, P, Welch, R., Berndt, SI, Hamid, A., Gago Dominguez, Manuela, Reid, A, Rosenstein, BS, Loveday, C., Thibodeau, S. N., Townsend, PA, Levy, M., Butt, M, Turnbull, C, Pashayan, N., Cole, D, White, J., McAteer, J., Nordestgaard, B. G., Penney, KL, Houlston, R. S., Seckl, M., Chakraborti, P, Joffe, J, Vega Gliemmo, Ana, Leahy, M., Gilby, E, Kelly, K, Simmonds, P.   +263 more
core   +1 more source

Codesign and Launch of ‘On the Ball’: An Inclusive Community‐Based ‘Testicular Awareness’ Campaign

Health Expectations
Introduction Increased awareness of testicular diseases can lead to early diagnosis. Evidence suggests that men's awareness of testicular diseases is low, with many expressing their willingness to delay help‐seeking for symptoms of concern.
Mohamad M. Saab, Varsha N. Shetty, Megan McCarthy, Martin P. Davoren, Angela Flynn, Ann Kirby, Steve Robertson, Gillian W. Shorter, David Murphy, Michael J. Rovito, Frances Shiely, Josephine Hegarty   +11 more
doaj   +1 more source

Epigenetic: a molecular link between testicular cancer and environmental exposures?

Frontiers in Endocrinology, 2012
In the last decades, studies in rodents have highlighted links between in utero and/or neonatal exposures to molecules that alter endocrine functions and the development of genital tract abnormalities, such as cryptorchidism, hypospadias, and impaired ...
Aurelie eVega, Marine eBaptissart, Françoise eCaira, Florence eBrugnon, Jean-Marc A Lobaccaro, David H VOLLE   +5 more
doaj   +1 more source

Ebselen alleviates testicular pathology in mice with Zika virus infection and prevents its sexual transmission. [PDF]

PLoS Pathogens, 2018
Despite the low case fatality, Zika virus (ZIKV) infection has been associated with microcephaly in infants and Guillain-Barré syndrome. Antiviral and vaccine developments against ZIKV are still ongoing; therefore, in the meantime, preventing the disease
Yogy Simanjuntak, Jian-Jong Liang, Si-Yu Chen, Jin-Kun Li, Yi-Ling Lee, Han-Chung Wu, Yi-Ling Lin   +6 more
doaj   +1 more source

The Prognostic Role of Neutrophil-to-Lymphocyte Ratio (NLR) in Testicular Germ Cell Tumor (GCT)

Folia Medica Indonesiana, 2022
Highlights: • Neutrophil to lymphocyte ratio (NLR) has been reported by several studies for its role as a biomarker in various diseases, however, the role of NLR in testicular GCT is still unclear.
Haviv Muris Saputra, Lukman Hakim
doaj   +1 more source

Transcriptional Profiling of Luteinizing Hormone Receptor-Deficient Mice Before and after Testosterone Treatment Provides Insight into the Hormonal Control of Postnatal Testicular Development and Leydig Cell Differentiation [PDF]

, 2010
Luteinizing hormone (LH) is a key regulator of male fertility through its effects on testosterone secretion by Leydig cells. Transcriptional control of this is, however, currently poorly understood.
Affara, Nabeel, Abel, M, Ellis, Peter J.I., Dunmore, B., Bauer, Johann W., Griffin, Darren K.   +5 more
core   +1 more source

Clinical evaluation of testicular torsion presenting with acute abdominal pain in young males

Asian Journal of Urology, 2019
Objective: To evaluate the features of testicular torsion presenting with acute abdominal pain and to raise awareness of testicular torsion with specific symptoms.
Fujun Wang, Zengnan Mo
doaj   +1 more source