Results 181 to 190 of about 70,701 (334)
Burned-out testicular cancer - case report
Introduction and Purpose Germ cell tumors of the testis are the most common malignant tumors in young men aged 15-40, although their incidence in the male population is about 1-1.5%. 90-98% of all testicular tumors originate from germ cells. There has
Mateusz Szarek+3 more
doaj +1 more source
STUDIES ON THE hCG-STAINED CELLS IN THE TESTICULAR GERM CELL TUMORS
Shuichi Gotoh
openalex +2 more sources
Deubiquitinase TRIM44 Promotes Autophagy‐Mediated Chemoresistance in Diffuse Large B Cell Lymphoma
ABSTRACT Diffuse large B cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin lymphoma. Tripartite motif containing 44 (TRIM44) belonging to the TRIM family, is involved in tumor development and is highly expressed in a variety of tumors. However, the role of TRIM44 in DLBCL remains undefined. Gain and loss‐of‐function studies were performed
Yan Wang+7 more
wiley +1 more source
Sarcoidosis, “sarcoid-like lymphadenopathy,” and testicular germ cell tumors
Guy C. Toner, George J. Bosl
openalex +1 more source
Microsatellite instability and loss of heterozygosity have distinct prognostic value for testicular germ cell tumor recurrence [PDF]
Alfredo Velasco+6 more
openalex +1 more source
Histopathological Features of the Testes of a Patient With Congenital Lipoid Adrenal Hyperplasia
ABSTRACT Introduction Congenital lipoid adrenal hyperplasia (CLAH) is a type of congenital adrenal hyperplasia characterized by reduced steroid production. Patients with this endocrine disorder as well as chromosome 46,XY have testes and female external genitalia. Because these individuals are usually raised as female, the testes are removed.
Takuya Sakata+9 more
wiley +1 more source
Summary: Testicular germ cell tumors (TGCTs) are among the most responsive solid cancers to conventional chemotherapy. To elucidate the underlying mechanisms, we developed a mouse TGCT model featuring germ cell-specific Kras activation and Pten ...
Timothy M. Pierpont+15 more
doaj
Epidermal growth factor receptor is a marker for syncytiotrophoblastic cells in testicular germ cell tumors [PDF]
The epidermal growth factor receptor (EGFR) has been implicated in the pathogenesis, therapy and prognosis of various tumor types. The aim of this study was to investigate EGFR expression in a large series of testicular germ cell tumors (TGCTs).
Hechelhammer, Lukas+4 more
core
Glutamine Metabolism: Molecular Regulation, Biological Functions, and Diseases
Tumor cells adapt to nutrient‐poor environments by altering metabolism to acquire essential nutrients. They convert glutamine into glutamate and α‐ketoglutarate, supporting mTOR activation and sugar biosynthesis. Disruption of mTORC1 signaling is linked to disease, while glutamine and leucine activation promotes cell growth and inhibits autophagy ...
Mudasir A. Kumar+10 more
wiley +1 more source