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Update on testicular germ cell tumors

Current Opinion in Oncology, 2011
This overview discusses several important developments in testicular germ cell tumors in the last year.Genomic studies are examining gene expression as possible markers for disease relapse and chemotherapy resistance. Optimal treatment strategies for early-stage nonseminomatous tumors continue to evolve, and advanced disease states continue to be ...
Heather D, Mannuel   +2 more
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Biology of testicular germ cell tumors

Expert Review of Anticancer Therapy, 2008
Germ cell tumors are derived from cells of the germ cell lineage and are the most common solid malignancies to affect young Caucasian men between the ages of 15 and 40 years. All testicular germ cell tumors develop from the same precursor lesion, intratubular germ cell neoplasia unclassified, which in turn is thought to arise from malignant ...
Syed A, Hussain   +4 more
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Update on testicular germ cell tumors

Current Opinion in Oncology, 2009
To discuss several important developments in testicular germ cell tumors in the past year.Genomic studies are examining gene expression as possible markers for disease relapse and chemotherapy resistance. Optimal treatment strategies for early-stage nonseminomatous tumors continue to evolve and patient compliance with posttreatment surveillance ...
Heather D, Mannuel, Arif, Hussain
openaire   +3 more sources

Multifocality in Testicular Germ Cell Tumors

Journal of Urology, 2009
Standard treatment for testicular germ cell tumor is radical orchiectomy. Several groups have suggested an organ sparing approach in patients with bilateral tumors or tumor in a solitary testis. We determined the prevalence of multifocality in testicular germ cell tumor cases.Orchiectomy specimens from 145 consecutive patients treated for testicular ...
Yaron, Ehrlich   +3 more
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Testicular Germ Cell Tumors

2017
Testicular cancer corresponds to approximately 1–2 % of tumors in men; however, they are the most common malignancy in those between the ages of 15 and 34. About 95 % of testicular tumors are germ cell tumors (GCT). Significant improvements in our understanding of the underlying pathogenesis and molecular biology in recent years have resulted in a new ...
Rafael E. Jimenez   +3 more
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Testicular Germ Cell Tumors

2009
Testicular tumors, of which the vast majority is of germ cell origin, are an important group of neoplasms because most of them are curable. The management of testicular cancer has been a major oncological success story and provides a model for the management of curative solid tumors.
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[Testicular germ cell tumors].

Bulletin du cancer, 1998
Testicle germ cells tumors are the most common young men neoplasm. The incidence is maximal in Scandinavian countries. Cryptorchidism is a predisposing factor. Diagnosis is clinic, first treatment is radical orchidectomy by inguinal incision, after study of tumor markers. Histology shows seminoma or non seminomatous tumor.
L M, Dourthe   +3 more
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Testicular germ cell tumor with pineal metastases

Neurosurgery, 1990
Abstract A patient with a mixed testicular germ cell tumor (choriocarcinoma, teratocarcinoma and embryonal carcinoma) that had metastasized to the lungs, cerebrum, and pineal gland is presented. The metastases had resulted in localized neurological signs and initially, on clinical grounds, a primary intracranial lesion could not be ...
B, Delahunt   +4 more
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Late Relapse in Testicular Germ Cell Tumors

Tumori Journal, 2007
Aims and Background Analysis of patients with late relapse of testicular germ cell tumors (GCTs) with reports on clinicopathological features and outcomes. Methods We identified all patients diagnosed with testicular GCTs at our Institute between 1988 and 2004 who developed relapse ≥24 months after completion of primary therapy.
Detti B   +6 more
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Pathology of Testicular Germ Cell Tumors

Hematology/Oncology Clinics of North America, 1991
The pathology report on a testicular germ cell tumor should include the following information: Tumor type: The histologic type of tumor present. If the tumor is of mixed type, the components should be listed, in order of relative abundance. The pathologist may endeavor to give a numeric estimate of the percentages of each element.
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