Results 111 to 120 of about 5,157,625 (240)

Improving the Understanding of Late Effects of Testicular Cancer in Adolescent and Young Adult Survivors: TRANSCEND‐XR

Andrology, EarlyView.
ABSTRACT Background Testicular cancer (TC) is the most common malignancy amongst adolescents and young adults (AYAs) aged 15–39 years assigned male at birth. Survivors often experience late effects of treatment and report unmet supportive care needs.
Mohamad M. Saab, Josephine Hegarty, Jack P. Gleeson, David Murphy, Sheena McHugh, Frances Shiely, Aileen Murphy, Ann Kirby, Ida J. Korfage, Sophie Terhaard, Agnes van der Heide, Johannes Sivesgaard, Matias Katajavaara Seidler, Anna Patrikidou, Davor Ježek, Lynda Corrigan, Patrice Kearney Sheehan, Daniele Raggi, Alison Reid, Michal Chovanec, Patrizia Gianntempo, Jourik A. Gietema, Justine Fleur van der Feen, Francisco Lupiáñez‐Villanueva, Ana Roca‐Umbert, Joanne Reid, Paulo Alves, Joana Soares, Karen Galvin, Michal Kubo, Maria O'Malley   +30 more
wiley   +1 more source

Oxaliplatin for the treatment of cisplatin-resistant cancer: a systematic review [PDF]

, 2007
Oxaliplatin is widely regarded as being active in cisplatin-resistant cancer. We undertook a systematic review of the literature to identify, describe and critique the clinical and pre-clinical evidence for the use of oxaliplatin in patients with ...
Pavlakis, Nick, Ross Davey, Davey, Ross, Nick Pavlakis, Britta Stordal, Stordal, Britta, Stordal, B., Pavlakis, N., Davey, R.   +8 more
core   +2 more sources

Neoplastic Risk in Patients With Klinefelter Syndrome

Andrology, EarlyView.
ABSTRACT Background Besides gonadal involvement (hypogonadism, male factor infertility, and testicular hypotrophy), patients with Klinefelter syndrome (KS) may suffer from several extra‐gonadic complications, including neoplastic events. Objective The aim of this review is to summarize all major clinical evidence dealing with the association between KS
Andrea Graziani, Giuseppe Grande, Riccardo Selice, Antonella Di Mambro, Alberto Ferlin   +4 more
wiley   +1 more source

Clinical and genetic aspects of testicular germ cell tumours

Hereditary Cancer in Clinical Practice, 2008
In this paper we review clinical and genetic aspects of testicular germ cell tumours (TGCTs). TGCT is the most common type of malignant disorder in men aged 15-40 years. Its incidence has increased sharply in recent years.
Holzik Martijn, Sijmons Rolf H, Hoekstra-Weebers Josette EHM, Sleijfer Dirk T, Hoekstra Harald J   +4 more
doaj   +1 more source

3. Sudden Death caused by Testicular Germ Cell Tumour

, 1995
Most cases of sudden unexpected ‘natural’ death are due to primary disorders of the cardiovascular, respiratory and central nervous system. Sudden death due to a previously undiagnosed malignancy is rare in young, apparently healthy subjects.
Mahomed A Dada, D J J Van Velden
core   +1 more source

Parallel Liquid Biopsy Analysis of miR‐371a‐3p and Cell‐Free DNA in an Unselected Cohort of Patients With Testicular Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Background Despite robust data showing strong potential to improve diagnosis and disease monitoring in testicular germ cell tumors (TGCTs), miR‐371a‐3p testing has not yet been implemented in routine clinical practice. Cell‐free DNA (cfDNA) represents another promising liquid biopsy biomarker that may provide complementary molecular ...
Laura Matouskova, Romy Kralova, Eva Parobkova, Violeta Bakardjieva‐Mihaylova, Martina Zwyrtkova, Karolina Skvarova Kramarzova, Ludmila Boublikova   +6 more
wiley   +1 more source

Giant testicular mixed germ cell tumour in an elderly patient: A case report

Urology Case Reports
Although germ cell tumours can appear in childhood, they are most common around the age of 30. These tumours are highly responsive to chemotherapy, and even cases of relapse have relatively high cure rates.
Reda Tariqi, Adam El Aboudi, Abdelmounim Boughaleb, Imad Boualaoui, Ahmed Ibrahimi, Hachem El Sayegh, Yassine Nouini   +6 more
doaj   +1 more source

Abstract 3703: A genomic characterization of testicular germ cell tumor immune microenvironment

, 2017
Testicular germ cell tumors (TGCT) are a histologically diverse set of tumors and the most common cancer type in young men. As part of the TCGA effort, we analyzed tumors from 133 patients including 4 patients with asynchronous double primary TGCTs (137 ...
Benjamin Vincent, Charles M. Perou, Daniel P. Hollern, Katie Hoadley, TCGA Testicular Germ Cell Tumor Analysis Working Group   +4 more
core   +1 more source

Impact of Treatment Intensity on Quality of Life in Patients With Metastatic Testicular Cancer

Andrology, EarlyView.
ABSTRACT Introduction Testicular cancer (TC) is the most common malignancy in young men and is highly curable with platinum‐based chemotherapy. With growing survivorship rates, treatment‐related symptom burden and quality of life (QoL) have become increasingly important.
Pailin Pongratanakul, Tamim Hadjizada, Sophia Thy, Marieke Vermeulen‐Spohn, Günter Niegisch, Peter Albers, Yue Che   +6 more
wiley   +1 more source

Impact of Testicular Germ Cell Tumor Laterality on Survival After Autologous Stem Cell Transplantation and High-Dose Chemotherapy [PDF]

Introduction: This study aimed to evaluate the effect of tumor localization on survival in patients undergoing autologous stem cell transplantation (ASCT), high-dose chemotherapy (HDCT) for recurrent/refractory testicular germ cell tumors (GCT). Methods:
Berkan Karadurmuş, Nurlan Mammadzada, Esmanur Kaplan Tüzün, Goncagül Akdağ, Ayşegül Dumludağ, Ömer Faruk Kuzu, Alper Topal, Nuri Karadurmuş   +7 more
core   +1 more source