Results 121 to 130 of about 5,157,625 (240)

Adenosine—A Regulator of Human Testicular Peritubular Cells

Andrology, EarlyView.
ABSTRACT Background Extracellular purines, in particular ATP and adenosine, are regulators of physiological and pathophysiological processes throughout the human body. Roles in the human testis are emerging and include actions on peritubular cells, which form the wall of seminiferous tubules.
Lina Scholz, Annika Liebich, Youli Stepanov, Jan B. Stöckl, Mirko Peitzsch, Michaela Schneider, Julia Schneider, Nicole Kreitmair, Matthias Trottmann, Frank‐Michael Köhn, Jovica Ninkovic, Thomas Fröhlich, Artur Mayerhofer   +12 more
wiley   +1 more source

Testicular germ cell tumour risk by occupation and industry: a French case-control study - TESTIS. [PDF]

Occup Environ Med, 2023
Guth M, Coste A, Lefevre M, Deygas F, Danjou A, Ahmadi S, Dananché B, Pérol O, Boyle H, Schüz J, Bujan L, Metzler-Guillemain C, Giscard d'Estaing S, Teletin M, Ducrocq B, Frapsauce C, Olsson A, Charbotel B, Fervers B, TESTIS study group.   +19 more
europepmc   +1 more source

Testisin, a new human serine proteinase expressed by premeiotic testicular germ cells and lost in testicular germ cell tumors [PDF]

, 1999
We have cloned and characterized a cDNA encoding a new human serine proteinase, testisin, that is abundantly expressed only in the testis and is lost in testicular tumors.
Antalis, T., Stuttgen, M., Loveland, K. A. L., Dickinson, Joanne L., Sutherland, Grant R., Nicol, D., Eyre, H., Normyle, J., Hooper, John D., Lakoski-Loveland, Kate A., Douglas, Meaghan L., Eyre, Helen J., Hooper, J. D., Stuttgen, Melanie A., Dickinson, J., Sutherland, G., Dickinson, J. L., Eyre, H. J., Hooper, J., Normyle, John F., Scarman, A., Antalis, T. M., Nicol, David L., Scarman, A. L., Stuttgen, M. A., Douglas, M., Loveland, K., Douglas, M. L., Antalis, Toni M., Normyle, J. F., Sutherland, G. R., Scarman, Anthony L., Nicol, D. L.   +32 more
core  

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

Single‐cell mRNA sequencing of giant panda (Ailuropoda melanoleuca) seminoma reveals the cellular and molecular characteristics of tumour cells

Veterinary Medicine and Science
Testicular tumours are zoonoses that can occur in not only human, but other animals, include giant pandas. A middle‐aged male giant panda named Fufu was diagnosed with a testicular tumour and underwent surgery to remove the entire left testis. The testis
Chen Yijiao, An Junhui, Hou Rong, Liu Yuliang, Wang Donghui, Liu Songrui, Feng Tongying   +6 more
doaj   +1 more source

Androgens Modulate Tumor–Immune Interactions in Testicular Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Background The majority of testicular germ cell tumors (TGCT) are derived from the germ cell neoplasia in situ and arise after puberty in the local presence of high levels of testosterone. The seminoma subtype features a rich inflammatory infiltrate which impacts tumor progression but the role of testosterone in shaping tumor–immune ...
Ida Hamann, Lucas Klaus, Patrick Fruth, Alexander Fichtner, Tobias J. Legler, Holger M. Reichardt, Fabian A. Gayer   +6 more
wiley   +1 more source

SLAMF6 Enhances the Efficacy of Anti‐PD‐L1 Immunotherapy in CRC Through the STAT1/CXCL10 Signaling Axis

Cancer Science, EarlyView.
SLAMF6 recruits SHP‐2 to activate STAT1, upregulates CXCL10 and PD‐L1, promotes CD8+T cell infiltration, and enhances the efficacy of anti‐PD‐L1 therapy. ABSTRACT As a T‐cell receptor co‐stimulatory protein, signaling lymphocyte activation molecule family 6 (SLAMF6) is a member of the immune cell activating receptor family and is expressed on T cells ...
Yu Wu, Xinhui Lv, Shunhao Zhang, Yafang Chen, Sicong Liu, Feiyang Song, Chunmei Zhao, Guihua Wang, Xudong Wang   +8 more
wiley   +1 more source

Risk of osteoporosis in testicular germ cell tumour survivors: A systematic review of the literature. [PDF]

BJUI Compass, 2023
Vrouwe JPM, Hennus PML, Hamdy NAT, Osanto S, Willemse PM.   +4 more
europepmc   +1 more source

microRNAs as novel biomarkers for patients with testicular germ cell tumours

, 2019
Testicular cancer is the most common malignancy in men aged 14 - 44 years. In clinical management of testicular germ cell tumours (TGCTs), measurement of biomarkers is essential. However, only
Spiekermann, Meike
core  

A Noncanonical Protein Degradation Pathway That Regulates Germ Cell Maintenance

Cell Proliferation, EarlyView.
SENP8 regulates a non‐canonical NEDD8‐dependent pathway to stabilize STAT1, promote CCL2/CCL5 transcription, and maintain germ cell proliferation and migration.
Meng Liu, Xiya Qiu, Wenying Qu, Yue Ma, Mingyuan Bao, Yuxuan Feng, Xiaochu Wang, Tao Zhou, Bo Zheng, Shunyu Hou, Yu Xia, Qingxia Meng   +11 more
wiley   +1 more source