Results 201 to 210 of about 5,157,625 (240)
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The Lancet, 2016
Testicular germ cell tumours are at the crossroads of developmental and neoplastic processes. Their cause has not been fully elucidated but differences in incidences suggest that a combination of genetic and environment factors are involved, with environmental factors predominating early in life.
Ewa, Rajpert-De Meyts +4 more
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Testicular germ cell tumours are at the crossroads of developmental and neoplastic processes. Their cause has not been fully elucidated but differences in incidences suggest that a combination of genetic and environment factors are involved, with environmental factors predominating early in life.
Ewa, Rajpert-De Meyts +4 more
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HMGA2 expression distinguishes between different types of postpubertal testicular germ cell tumour
Journal of Pathology: Clinical Research, 2015 The group of postpubertal testicular germ cell tumours encompasses lesions with highly diverse differentiation – seminomas, embryonal carcinomas, yolk sac tumours, teratomas and choriocarcinomas.
Gazanfer Belge +2 more
exaly +2 more sources
Occult Germ‐cell Testicular Tumours
British Journal of Urology, 1983Summary— Eighteen men presenting with metastatic germ‐cell malignancy in whom no primary tumour could be palpated in either testis are described. All patients had both testes in the scrotal sac and none had a history of maldescent.
S, Powell, W F, Hendry, M J, Peckham
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Pathogenesis of testicular germ cell tumours
Reviews of Reproduction, 1999Human germ cell tumours comprise a heterogeneous group of neoplasms. In the testis, three entities are distinguished, the teratomas-yolk sac tumours of the infantile testis, the seminomas and nonseminomas of adolescents and adults, and the spermatocytic seminomas.
L H, Looijenga, J W, Oosterhuis
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Epigenetic alterations of testicular germ cell tumours
Current Opinion in Urology, 2020Purpose of review Testicular germ cell tumours (TGCTs) exhibit, in contrast to other cancer types, a relatively low mutational burden. However, numerous epigenetic alterations have been shown to impact TGCT. In this review, we summarize the most relevant findings of the past 2 years.
Dafina, Ilijazi +4 more
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Pathogenesis of Testicular Germ Cell Tumours
European Urology, 1993Testicular germ cell tumours are subdivided clinically into two major groups: seminomas and non-seminomatous germ cell tumours (NSGCT). The relationship of seminomas to NSGCT remains controversial. The pathogenesis of NSGCT has been studied experimentally in mice, but there are no adequate experimental models of seminomas in laboratory rodents ...
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Staging of testicular germ cell tumours
Clinical Radiology, 1993Testicular germ cell tumours occupy a place of particular importance in modern oncology. They afflict young men, often at the peak of their social and economic responsibilities. The incidence has been rising throughout this century and almost doubled between the periods 1964-68 and 1979-82, such that figures from 1981 indicated that in England and ...
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International journal of biochemistry & cell biology, 2005
Testicular germ cell tumours (TGCTs) are the most frequent solid malignant tumour in men 20-40 years of age and the most frequent cause of death from solid tumours in this age group. Up to 50% of the patients suffer from metastatic disease at diagnosis.
di Pietro, A +4 more
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Testicular germ cell tumours (TGCTs) are the most frequent solid malignant tumour in men 20-40 years of age and the most frequent cause of death from solid tumours in this age group. Up to 50% of the patients suffer from metastatic disease at diagnosis.
di Pietro, A +4 more
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Testicular germ cell tumour presenting as thyrotoxicosis
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2004A case is reported of a patient who presented to his family doctor with a short history of cough with signs and symptoms of thyrotoxicosis. Carbimazole treatment had little effect and his symptoms worsened to include severe shortness of breath. He was investigated further and found to have multiple lung and liver metastases from an unknown primary site.
L K, Tilbrook, J, Slater, A D, Blainey
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Genomic imprinting in testicular germ cell tumours
APMIS, 1998Genomic imprinting refers to the parental origin‐specific functional difference between the paternally and maternally‐derived mammalian haploid genome. Normal embryogenesis depends on the presence of both a paternal and a maternal copy of particular chromosomal regions, containing the so‐called imprinted genes.
L H, Looijenga +5 more
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