Results 41 to 50 of about 5,157,625 (240)

Cisplatin-based chemotherapy of testicular cancer - Two decades after a major breakthrough [PDF]

open access: yes, 2000
Two decades ago the introduction of cisplatin-based combination chemotherapy has dramatically improved the prognosis of patients with metastatic testicular cancer, At present 3 cycles of cisplatin, etoposide and bleomycin are considered as standard ...
Gerl, Arthur
core   +1 more source

LEYDIG CELL TUMOUR OF THE RIGHT TESTICLE IN AN ELEVEN YEAR OLD LABRADOR DOG [PDF]

open access: yesJournal of Veterinary and Animal Sciences, 2016
Testicular tumours are the second most common tumour in male dogs. Primary testicular tumours account for about 90 per cent of all tumours affecting the male genitalia (Hayes and Pendergrass, 1976).
B. Bibin Becha   +4 more
doaj  

Retroperitoneal teratoma with somatic malignant transformation: A papillary renal cell carcinoma in a testicular germ cell tumour metastasis following platinum-based chemotherapy

open access: yesBMC Urology, 2013
Background Malignant transformation describes the phenomenon in which a somatic component of a germ cell teratoma undergoes malignant differentiation.
Zeh Nina   +6 more
doaj   +1 more source

Epigenetic profile of testicular germ cell tumours [PDF]

open access: yesInternational Journal of Andrology, 2007
SummaryDNA methylation is the best known and most thoroughly studied epigenetic mechanism. Hypermethylation of CpG islands associated with silencing of tumour suppressor genes or tumour‐related genes is a common hallmark of human cancer. The list of tumour‐related genes with aberrant hypermethylation in their CpG islands has been increasing.
Keisei, Okamoto, Takahiro, Kawakami
openaire   +2 more sources

Testicular Germ Cell Tumours and Proprotein Convertases

open access: yesCancers, 2022
Testicular Germ Cell Tumours (TGCT) are widely considered a “curable cancer” due to their exceptionally high survival rate, even if it is reduced by many years after the diagnosis due to metastases and relapses. The most common therapeutic approach to TGCTs has not changed in the last 50 years despite its multiple long-term side effects, and because it
Aitziber Velado-Eguskiza   +4 more
openaire   +3 more sources

Baldness, acne and testicular germ cell tumours [PDF]

open access: yesInternational Journal of Andrology, 2010
SummaryAndrogen levels during critical periods of testicular development may be involved in the aetiology of testicular germ cell tumours (TGCT). We evaluated the roles of adolescent and early adult life correlates of androgen exposure and TGCT in a hospital‐based case–control study. TGCT cases (n = 187) and controls (n = 148), matched on age, race and
B, Trabert   +5 more
openaire   +2 more sources

Paratesticular Rhabdomyosarcoma in Young Adult- A Case Report [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2015
Para testicular rhabdomyosarcoma is a rare malignant tumour, which usually presents as a painless mass in the scrotum or groin. A case of para testicular rhabdomyosarcoma in a 17-year-old male is being reported here who presented with chronic scrotal ...
NAVIN KUMAR SINHA
doaj   +1 more source

Cutaneous metastasis from testicular germ cell tumour

open access: yesIndian Journal of Urology, 2014
The skin is an unusual site of metastases from solid organ malignancies. We report the case of a patient with a malignant mixed non-seminomatous germ cell tumor of the testis, presenting with cutaneous metastasis, which was treated with salvage ...
Anjana Joel   +3 more
doaj   +1 more source

Cisplatin-Based Chemotherapy for Pulmonary Metastasized Germ Cell Tumors of the Testis - Be Aware of Acute Respiratory Distress Syndrome [PDF]

open access: yes, 2009
Background: Cisplatin-based combination chemotherapy is regarded as standard of care for patients with advanced germ cell tumors. In patients with lung metastases and a high tumor load, an association between induction chemotherapy and the development of
Parhofer, Klaus G.   +6 more
core   +1 more source

Identification of ERβ1 and ERβ2 in human seminoma, in embryonal carcinoma and in their adjacent intratubular germ cell neoplasia

open access: yesReproductive Biology and Endocrinology, 2009
Background Estrogens exert a role on germ cell physiology of normal human testis through the mediation of the estrogen receptor (ER) beta subtypes. Epidemiological studies evidenced an increased incidence of testicular germ cell cancer after elevated pre-
Rago Vittoria   +5 more
doaj   +1 more source

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