Results 41 to 50 of about 5,157,625 (240)
Cisplatin-based chemotherapy of testicular cancer - Two decades after a major breakthrough [PDF]
Two decades ago the introduction of cisplatin-based combination chemotherapy has dramatically improved the prognosis of patients with metastatic testicular cancer, At present 3 cycles of cisplatin, etoposide and bleomycin are considered as standard ...
Gerl, Arthur
core +1 more source
LEYDIG CELL TUMOUR OF THE RIGHT TESTICLE IN AN ELEVEN YEAR OLD LABRADOR DOG [PDF]
Testicular tumours are the second most common tumour in male dogs. Primary testicular tumours account for about 90 per cent of all tumours affecting the male genitalia (Hayes and Pendergrass, 1976).
B. Bibin Becha +4 more
doaj
Background Malignant transformation describes the phenomenon in which a somatic component of a germ cell teratoma undergoes malignant differentiation.
Zeh Nina +6 more
doaj +1 more source
Epigenetic profile of testicular germ cell tumours [PDF]
SummaryDNA methylation is the best known and most thoroughly studied epigenetic mechanism. Hypermethylation of CpG islands associated with silencing of tumour suppressor genes or tumour‐related genes is a common hallmark of human cancer. The list of tumour‐related genes with aberrant hypermethylation in their CpG islands has been increasing.
Keisei, Okamoto, Takahiro, Kawakami
openaire +2 more sources
Testicular Germ Cell Tumours and Proprotein Convertases
Testicular Germ Cell Tumours (TGCT) are widely considered a “curable cancer” due to their exceptionally high survival rate, even if it is reduced by many years after the diagnosis due to metastases and relapses. The most common therapeutic approach to TGCTs has not changed in the last 50 years despite its multiple long-term side effects, and because it
Aitziber Velado-Eguskiza +4 more
openaire +3 more sources
Baldness, acne and testicular germ cell tumours [PDF]
SummaryAndrogen levels during critical periods of testicular development may be involved in the aetiology of testicular germ cell tumours (TGCT). We evaluated the roles of adolescent and early adult life correlates of androgen exposure and TGCT in a hospital‐based case–control study. TGCT cases (n = 187) and controls (n = 148), matched on age, race and
B, Trabert +5 more
openaire +2 more sources
Paratesticular Rhabdomyosarcoma in Young Adult- A Case Report [PDF]
Para testicular rhabdomyosarcoma is a rare malignant tumour, which usually presents as a painless mass in the scrotum or groin. A case of para testicular rhabdomyosarcoma in a 17-year-old male is being reported here who presented with chronic scrotal ...
NAVIN KUMAR SINHA
doaj +1 more source
Cutaneous metastasis from testicular germ cell tumour
The skin is an unusual site of metastases from solid organ malignancies. We report the case of a patient with a malignant mixed non-seminomatous germ cell tumor of the testis, presenting with cutaneous metastasis, which was treated with salvage ...
Anjana Joel +3 more
doaj +1 more source
Cisplatin-Based Chemotherapy for Pulmonary Metastasized Germ Cell Tumors of the Testis - Be Aware of Acute Respiratory Distress Syndrome [PDF]
Background: Cisplatin-based combination chemotherapy is regarded as standard of care for patients with advanced germ cell tumors. In patients with lung metastases and a high tumor load, an association between induction chemotherapy and the development of
Parhofer, Klaus G. +6 more
core +1 more source
Background Estrogens exert a role on germ cell physiology of normal human testis through the mediation of the estrogen receptor (ER) beta subtypes. Epidemiological studies evidenced an increased incidence of testicular germ cell cancer after elevated pre-
Rago Vittoria +5 more
doaj +1 more source

