Results 31 to 40 of about 416,184 (321)

Adenocarcinoma Originating from a Mature Teratoma of the Testis

Kaohsiung Journal of Medical Sciences, 2007
Malignant transformation in testicular teratomas has been reported very rarely in the literature. Although testicular teratomas in childhood are regarded as benign neoplasms, these tumors, if left untreated until advanced ages, may present the risk of ...
Resit Dogan Koseoglu, Bekir Suha Parlaktas, Nurper Onuk Filiz, Fikret Erdemir, Nihat Uluocak, Ozden Tulunay   +5 more
doaj   +1 more source

Phase 2 results of lisocabtagene maraleucel in Japanese patients with relapsed/refractory aggressive B‐cell non‐Hodgkin lymphoma

Cancer Medicine, Volume 11, Issue 24, Page 4889-4899, December 2022., 2022
This analysis assessed safety and efficacy of lisocabtagene maraleucel (liso‐cel), an autologous CD‐19‐directed CAR T‐cell product, in Japanese patients with R/R aggressive LBCL in Cohort 3 of TRANSCEND WORLD (NCT03484702). Liso‐cel demonstrated meaningful efficacy and a manageable safety profile in Japanese patients with R/R LBCL.
Shinichi Makita, Go Yamamoto, Dai Maruyama, Yuki Asano‐Mori, Daisuke Kaji, Revathi Ananthakrishnan, Ken Ogasawara, Lara Stepan, Claudia Schusterbauer, Nils Rettby, Jens Hasskarl, Koji Izutsu   +11 more
wiley   +1 more source

Mathematical modelling, selection and hierarchical inference to determine the minimal dose in IFN$α$ therapy against Myeloproliferative Neoplasms [PDF]

Mathematical Medicine and Biology: A Journal of the IMA, Volume 41, Issue 2, June 2024, Pages 110-134, 2021
Myeloproliferative Neoplasms (MPN) are blood cancers that appear after acquiring a driver mutation in a hematopoietic stem cell. These hematological malignancies result in the overproduction of mature blood cells and, if not treated, induce a risk of cardiovascular events and thrombosis. Pegylated IFN$\alpha$ is commonly used to treat MPN, but no clear
arxiv   +1 more source

Inhibin-α, E-cadherin, calretinin and Ki-67 antigen in the immunohistochemical evaluation of canine and human testicular neoplasms.

Folia Histochemica et Cytobiologica, 2015
INTRODUCTION The steady increase of dogs with diagnosed testicular neoplasms observed in recent years prompted us to carry out immunohistochemical (IHC) studies for their better characterization.
R. Ciaputa, M. Nowak, J. Madej, D. Poradowski, I. Janus, P. Dzięgiel, E. Górzyńska, M. Kandefer-Gola   +7 more
semanticscholar   +1 more source

Idiopathic chronic hematocele of the vaginal sac

International Brazilian Journal of Urology, 2005
We report a 39-year-old male who presented non-traumatic testicular swelling and pain. Physical examination and sonography presented a suspicion of testicular tumor and both surgical exploration and inguinal orchiectomy were performed.
Carlos Alvarez-Alvarez, Luis A. Farina-Perez, Celso R. Barros   +2 more
doaj   +1 more source

Semiparametric regression in testicular germ cell data [PDF]

Annals of Applied Statistics 2012, Vol. 6, No. 3, 1185-1208, 2010
It is possible to approach regression analysis with random covariates from a semiparametric perspective where information is combined from multiple multivariate sources. The approach assumes a semiparametric density ratio model where multivariate distributions are "regressed" on a reference distribution.
arxiv   +1 more source

Primary neuroendocrine tumor of the testis

Urology Annals, 2014
Testicular neuroendocrine tumor is rare. It accounts for less than 1% of all testicular neoplasms. More than 60 cases have been published in the literature.
Shakir Alsharif, Mubarak Al-Shraim, Ahmed Alhadi, Abdulrahman Al-Aown, Fawzy Fooshang, Refat Eid   +5 more
doaj   +1 more source

The protective effects of rutin on the liver, kidneys, and heart by counteracting organ toxicity caused by synthetic and natural compounds

Food Science &Nutrition, Volume 11, Issue 1, Page 39-56, January 2023., 2023
Rutin is a flavonoid present in many plant species. Because of its antioxidant, anti‐inflammatory, and anti‐apoptotic properties, rutin is of interest for its potential protective effects against toxic agents. Rutin has potential therapeutic effectiveness against several toxicants, and its beneficial effects are more than likely mediated by its ...
Sohrab Rahmani, Karim Naraki, Ali Roohbakhsh, A. Wallace Hayes, Gholamreza Karimi   +4 more
wiley   +1 more source

The potential role of MR based radiomic biomarkers in the characterization of focal testicular lesions

Scientific Reports, 2021
How to differentiate with MRI-based techniques testicular germ (TGCTs) and testicular non-germ cell tumors (TNGCTs) is still under debate and Radiomics may be the turning key.
Giacomo Feliciani, Lorenzo Mellini, Aldo Carnevale, Anna Sarnelli, Enrico Menghi, Filippo Piccinini, Emanuela Scarpi, Emiliano Loi, Roberto Galeotti, Melchiore Giganti, Gian Carlo Parenti   +10 more
doaj   +1 more source

Germline selection of PTPN11 (HGNC:9644) variants make a major contribution to both Noonan syndrome's high birth rate and the transmission of sporadic cancer variants resulting in fetal abnormality

Human Mutation, Volume 43, Issue 12, Page 2205-2221, December 2022., 2022
Mutation frequency heat map of spontaneous PTPN11 variants show spatial clustering in the testis due to germline selection explaining the high birth incidence of Noonan syndrome. Some somatic PTPN11 cancer mutations are similarly clustered in testis. Abstract Some spontaneous germline gain‐of‐function mutations promote spermatogonial stem cell clonal ...
Jordan Eboreime, Soo‐Kyung Choi, Song‐Ro Yoon, Anastasiia Sadybekov, Vsevolod Katritch, Peter Calabrese, Norman Arnheim   +6 more
wiley   +1 more source