Results 41 to 50 of about 179,138 (280)

Testicular neoplasms in Kenyan Africans [PDF]

Cancer, 1978
Over a 9-year period 40 testicular and paratesticular neoplasms were seen at the Kenyatta National Hospital, Nairobi, Kenya. Their incidence rate was 0.08 per annum per 100,000 Kenyan males. This low incidence was largely accounted for by a decrease in tumors of germ cell origin.
Zimmerman, R. R., Kung'u, A.
openaire   +2 more sources

Neoangiogenesis in the dynamics of testicular seminoma progression

Journal of Education, Health and Sport, 2019
Testicular germ cell tumors (TGCT) is a group of neoplasms which develop from the germ cell epithelium and account 94-96% of all testicular tumors. Seminoma is the most common testicular germ cell neoplasm and accounts for about 50% of all TGCT.There is ...
S. M. Potapov, O. M. Pliten, N. I. Horhol   +2 more
doaj   +1 more source

The potential role of MR based radiomic biomarkers in the characterization of focal testicular lesions

Scientific Reports, 2021
How to differentiate with MRI-based techniques testicular germ (TGCTs) and testicular non-germ cell tumors (TNGCTs) is still under debate and Radiomics may be the turning key.
Giacomo Feliciani, Lorenzo Mellini, Aldo Carnevale, Anna Sarnelli, Enrico Menghi, Filippo Piccinini, Emanuela Scarpi, Emiliano Loi, Roberto Galeotti, Melchiore Giganti, Gian Carlo Parenti   +10 more
doaj   +1 more source

Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14. [PDF]

, 2013
Testicular germ cell tumor (TGCT) is the most common cancer in young men and is notable for its high familial risks. So far, six loci associated with TGCT have been reported.
Robert A Huddart, Sheila Seal, Eeles, Rosalind, Kote-Jarai, Zsofia, Elliot, Anna, Ruark, E, McDonald, Heather, Peto, Julian, D Timothy Bishop, Muir, K; id_orcid, Stratton, Michael R, Seal, Sheila, Turnbull, Clare, Kote-Jarai, Z, Muir, Kenneth (Kenneth R.), Kenneth Muir, Perdeaux, Elizabeth, Easton, Douglas F, McDonald, H, Zhang, Feng, Easton, Douglas F., Elizabeth Rapley, Muir, K, Seal, S, Janet Shipley, Perdeaux, E, Stratton, MR, Feng Zhang, KingWai Lau, Rahman, N, Huddart, RA, Bishop, DT, Rapley, Elizabeth, Rosalind Eeles, Stratton, Michael R., Huddart, Robert A, Heather McDonald, Huddart, R A, Nazneen Rahman, Muir, Kenneth, Elise Ruark, Shipley, Janet, McDonald, H. (Heather), UK Testicular Cancer Collaboration (UKTCC), Michael R Stratton, Anna Elliot, Nsengimana, J, Eeles, R, Jeremie Nsengimana, Elliot, A, Douglas F Easton, Shipley, J, UK Testicular Cancer Collaboration (UKTCC),, Turnbull, C, Elizabeth Perdeaux, Zsofia Kote-Jarai, Rapley, E. (Elizabeth), Bishop, D. Timothy (David Timothy), Clare Turnbull, Peto, J, Stratton, M R, Lau, Kingwai, Lau, K, Nsengimana, Jeremie, Ruark, Elise, Bishop, D Timothy, Easton, DF, Zhang, F, Rahman, Nazneen, Easton, D F, Rapley, E, Julian Peto, Bishop, D T, Huddart, Robert A.   +73 more
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Fine needle aspiration cytology and cell block in the diagnosis of seminoma testis

Journal of Cytology, 2011
Testicular neoplasms which show a wide variety of morphologic types, comprise a small proportion of malignancies. Early identification and treatment is essential for achieving long term survival.
Abhishant Pandey, N M Nandini, A K Jha, G V Manjunath   +3 more
doaj   +1 more source

Studies on the clinical significance of nonesterified and total cholesterol in urine [PDF]

, 1981
Gas-liquid chromatographic determinations of nonesterified and total urinary cholesterol were performed in 137 normals, 264 patients with various internal diseases without evidence of neoplasias or diseases of the kidney or urinary tract, 497 patients ...
Stadler, Alexander, Wallner, J., Eiermann, W., Jüngst, Dieter, Pickel, A., Marx, Franz J., Karl, Hans Josef   +6 more
core   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Large cell type B primary testicular lymphoma: clinical, histopathological, therapeutic diagnosis and prognostic aspects

Archivo Médico de Camagüey, 2020
Background: testicular lymphoma constitutes between 1 and 9 % of testicular tumors; it is the most frequent malignant testicular tumor in men over 50 years of age. The prognosis is reserved due to a great tendency to early systemic spread.
Elena Pérez-Rodriguez, Jesica del Pilar García-Pérez, José Alberto Hermida-Pérez, José Samuel Hernández-Guerra   +3 more
doaj  

Epigenetic Activation of SOX11 in Lymphoid Neoplasms by Histone Modifications [PDF]

, 2011
Recent studies have shown aberrant expression of SOX11 in various types of aggressive B-cell neoplasms. To elucidate the molecular mechanisms leading to such deregulation, we performed a comprehensive SOX11 gene expression and epigenetic study in stem ...
Amador Virginia, Ott, G. (German), Royo Cristina, Palomero, J. (Jara), Agirre, Xabier, Salaverria Frigola, Itziar, Manel Esteller, Román-Gómez, José, Esteller, Manel, Balazs Balint, Andreas Rosenwald, Xargay-Torrent Silvia, Martín-Guerrero Idoia, Rosenwald, Andreas, Campo, E. (Elías), Pedro Jares, Royo Moreno, Cristina, Royo, Cristina, Hernández, Luis, Vegliante Maria Carmela, Rosenwald Andreas, Siebert, Reiner, Siebert Reiner, Martin-Guerrero, I. (Idoia), Balint, B. (Balazs), Jares, P. (Pedro), Calasanz María José, Prosper Felipe, Esteller Manel, Palomero Jara, Reiner Siebert, Agirre Xabier, Calasanz, María José, Bea Silvia, Roman-Gomez José, Vegliante, M.C. (Maria Carmela), Campo Elias, Silvia Bea, Lujambio, A. (Amaya), Beà Bobet, Sílvia M., Jose Calasanz, Maria, Roman-Gomez, J. (José), Vegliante, Maria Carmela, Maria Carmela Vegliante, María José Calasanz, Balint Balazs, Luis Hernandez, Enjuanes Anna, Enjuanes, A. (Anna), Felipe Prosper, Balint, Balazs, Martin-Subero, J.I. (Jose Ignacio), Salaverria, Itziar, Richter, Julia, Martín Guerrero, Idoia, Ott, German, Jares Gerboles, Pedro, Xargay-Torrent, S. (Silvia), Martín-Subero José I., Amaia Lujambio, Cristina Royo, José Roman-Gomez, José I Martín-Subero, Maria Carmela Vegliante, Martin-Guerrero, Idoia, Anna Enjuanes, Carmela Vegliante, Maria, Salaverria-Lete, I. (Itziar), Richter, J. (Julia), Esteller, M. (Manel), Martin-Subero, Jose I., Richter Julia, Bea, Silvia, Rosenwald, A. (Andreas), Xargay-Torrent, Silvia, Jares Pedro, Royo, C. (Cristina), Prosper-Cardoso, F. (Felipe), Campo Güerri, Elias, José I. Martín-Subero, Campo, Elias, Idoia Martín-Guerrero, Ott German, Calasanz-Abinzano, M.J. (Maria Jose), Lujambio, Amaia, Hernandez, L. (Luis), Palomero, Jara, Silvia Xargay-Torrent, Jares, Pedro, Hernandez Luis, Lujambio Amaia, Virginia Amador, German Ott, Jara Palomero, Bea, S. (Silvia), Elias Campo, Amador, V. (Virginia), Xargay i Torrent, Sílvia, Julia Richter, Salaverria Itziar, Siebert, R. (Reiner), Amador, Virginia, Enjuanes, Anna, Aguirre-Ena, X. (Xabier), Itziar Salaverria, Prosper, Felipe, Xabier Agirre, Esteller, Manel, 1968-   +107 more
core   +1 more source