Results 41 to 50 of about 48,388 (273)
Background: testicular lymphoma constitutes between 1 and 9 % of testicular tumors; it is the most frequent malignant testicular tumor in men over 50 years of age. The prognosis is reserved due to a great tendency to early systemic spread.
Elena Pérez-Rodriguez +3 more
doaj
Adenomatoid tumor in a young male case report
Adenomatoid tumors are benign para-testicular tumors and account for about 30% of all paratesticular neoplasms in males. The most common presentation is scrotal swelling between the third and fifth decades.
Dalal Alhusainan +4 more
doaj +1 more source
An in vitro testicular model is developed by generating connective tissue equivalents from human dermal fibroblast‐derived microtissues and coupling them with human Sertoli cells or human Sertoli cell spheroids. This engineered microenvironment supports Sertoli cell maturation and functionality, providing a promising platform for studying human ...
Annachiara Scalzone +4 more
wiley +1 more source
Is there a causal association between genotoxicity and the imposex effect? [PDF]
There is a growing body of evidence that indicates common environmental pollutants are capable of disrupting reproductive and developmental processes by interfering with the actions of endogenous hormones.
Josephine A. Hagger +13 more
core +1 more source
β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto +20 more
wiley +1 more source
Rare complication of chemotherapy in testicular cancer [PDF]
Testicular neoplasms metastasizing to the retroperitoneum rarely involve the upper gastrointestinal tract. We describe an unusual case of contained small bowel perforation as a complication of chemotherapy treatment of metastatic non seminomatous germ ...
Goad Abdel Helmy Ehab
doaj +1 more source
Classical gonadoblastoma: its relationship to the “dissecting” variant and undifferentiated gonadal tissue [PDF]
Classical gonadoblastoma occurs almost entirely in the dysgenetic gonads of an individual who has a disorder of sex development. Approximately 40% of such neoplasms are bilateral.
Cheng, Liang, Roth, Lawrence M.
core +2 more sources
GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source
A Stranger in the Epididymis: Ectopic Spleen
Splenogonadal fusion, which can be clinically confused with testicular neoplasms as they present with testicular swelling, is a rare abnormality in young adults.
Yelda Dere +3 more
doaj +1 more source
Teratocarcinoma In A Non Seminomatous, Mixed Germ Cell Tumour of the Testis–A Rare Entity [PDF]
Mixed Germ Cell Tumours (MGCTs) of the testis are the second most common testicular tumours. In the 10 years retrospective study which was done on testicular neoplasms at our institute, this reported case accounted for 0.4%. We are presenting the case
Gayathri Malavalli +2 more
doaj +1 more source

