Results 41 to 50 of about 190,855 (262)

Socio-economic inequalities in testicular cancer survival within two clinical studies. [PDF]

, 2012
BACKGROUND: Testicular cancer is the most common cancer in men under 35 years of age, and has the highest survival for adult male malignancies. Despite the fact that survival is very high, there is evidence that survival differs between socio-economic ...
Read, Graham, Michel P. Coleman, Stenning, Sally, Cooper, Nicola, Coleman, Michel P., Graham Read, Parmar, Mahesh KB, Oliver, Tim, Mathew R. Sydes, Malcolm Mason, Nicola Cooper, Nur, Ula, Bernard Rachet, Mahesh K.B. Parmar, Parmar, Mahesh K. B., Coleman, Michel P, Sydes, Mathew R, Sydes, Mathew R., Ula Nur, Mason, Malcolm David, Tim Oliver, Rachet, Bernard, Mason, Malcolm, Sally Stenning   +23 more
core   +1 more source

Large cell type B primary testicular lymphoma: clinical, histopathological, therapeutic diagnosis and prognostic aspects

Archivo Médico de Camagüey, 2020
Background: testicular lymphoma constitutes between 1 and 9 % of testicular tumors; it is the most frequent malignant testicular tumor in men over 50 years of age. The prognosis is reserved due to a great tendency to early systemic spread.
Elena Pérez-Rodriguez, Jesica del Pilar García-Pérez, José Alberto Hermida-Pérez, José Samuel Hernández-Guerra   +3 more
doaj  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Testicular Carcinomas and Carcinoma of the Prostate [PDF]

, 1978
Testicular neoplasms are relatively rare with approximately two new cases per 100,000 male population occurring per year. The peak occurrence is between the ages of 20 and 40. Because of their highly malignant characteristics testicular neoplasms must be
Schellhammer, Paul F.
core  

Imaging in Testicular Tumors [PDF]

, 2023
It is the purpose of this article to describe and discuss the relative roles of these imaging modalities in the diagnosis of testicular neoplasms and work-up of metastatic disease. The ultimate role of MRl has yet to be evaluated.
Bao-Shan Jing, Sidney Wallace, Farzin Eftekhari   +2 more
core   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Androgen action via testicular arteriole smooth muscle cells is important for leydig cell function, vasomotion and testicular fluid dynamics [PDF]

, 2010
Regulation of blood flow through the testicular microvasculature by vasomotion is thought to be important for normal testis function as it regulates interstitial fluid (IF) dynamics which is an important intra-testicular transport medium.
Bergh, A., Sigrid Kilter, Richard M. Sharpe, Philippa T K Saunders, Lindsey Moffat, Sharpe, R.M., Welsh Michelle, Welsh, M., Anders Bergh, Philippa T. K. Saunders, Atanassova Nina, Saunders Philippa T. K., Atanassova, N., Smith, Lee B., Richard M Sharpe, Bergh, Anders, Bergh, Anders,, Kilter Sigrid, Sharpe, Richard M, Michelle Welsh, Sharpe Richard M., Moffat Lindsey, Lee B. Smith, Sharpe, Richard M., Moffat, Lindsey, Smith, L.B., Lee B Smith, Saunders, P.T.K., Kilter, Sigrid, Bergh Anders, Saunders, Philippa T. K.; id_orcid, Welsh, Michelle, Saunders, Philippa TK, Nina Atanassova, Smith Lee B., Smith, Lee B, Moffat, L., Kilter, S., Kilter, Sigrid,, Atanassova, Nina   +39 more
core   +1 more source

Teratocarcinoma In A Non Seminomatous, Mixed Germ Cell Tumour of the Testis–A Rare Entity [PDF]

Journal of Clinical and Diagnostic Research, 2013
Mixed Germ Cell Tumours (MGCTs) of the testis are the second most common testicular tumours. In the 10 years retrospective study which was done on testicular neoplasms at our institute, this reported case accounted for 0.4%. We are presenting the case
Gayathri Malavalli, Shilpa Karra, Bharathi Muniyappa   +2 more
doaj   +1 more source

Adenomatoid tumor in a young male case report

Urology Case Reports, 2023
Adenomatoid tumors are benign para-testicular tumors and account for about 30% of all paratesticular neoplasms in males. The most common presentation is scrotal swelling between the third and fifth decades.
Dalal Alhusainan, Saleh Bubishate, Ahmed Alharmi, Ahmed Elabd, Mustafa Almahmid   +4 more
doaj   +1 more source

SOX30 Facilitates Triple‐Negative Breast Cancer Metastasis via TNFR2–NF‐κB Signaling and Tumor Microenvironment Remodeling

Advanced Science, EarlyView.
SOX30 drives triple‐negative breast cancer (TNBC) metastasis through a dual mechanism: direct activation of the TNFR2/NF‐κB signaling cascade and subsequent CCL20‐mediated recruitment of tumor‐associated macrophages (TAMs) into the tumor microenvironment.
Pingping Gao, Na Sun, Ning Yang, Tingting Zhao, Rui Fu, Zhenyu Wu, Yuqin Zhou, Xuanni Tan, Yi Zhang, Fei Han, Xiaowei Qi   +10 more
wiley   +1 more source