Results 31 to 40 of about 48,388 (273)

A prospective study on contrast-enhanced magnetic resonance imaging of testicular lesions: distinctive features of Leydig cell tumours [PDF]

open access: yes, 2015
OBJECTIVES: Up to 20 % of incidentally found testicular lesions are benign Leydig cell tumours (LCTs). This study evaluates the role of contrast-enhanced magnetic resonance imaging (MRI) in the identification of LCTs in a large prospective cohort study.
BERNARDO, SILVIA   +11 more
core   +1 more source

The potential role of MR based radiomic biomarkers in the characterization of focal testicular lesions

open access: yesScientific Reports, 2021
How to differentiate with MRI-based techniques testicular germ (TGCTs) and testicular non-germ cell tumors (TNGCTs) is still under debate and Radiomics may be the turning key.
Giacomo Feliciani   +10 more
doaj   +1 more source

Advanced head and neck cancer: Long-term results of chemo-radiotherapy, complications and induction of second malignancies [PDF]

open access: yes, 2001
Background: Chemo-radiotherapy is superior to radiotherapy alone in the treatment of advanced, inoperable head and neck cancer. The long-term treatment results, the induction of second malignant tumors, and other long-term toxicities are not well defined.
Aydemir, Ü.   +6 more
core   +1 more source

Mixed germ cell sex cord-stromal tumors of the testis and ovary. Morphological, immunohistochemical, and molecular genetic study of seven cases [PDF]

open access: yes, 2006
We present the morphological, immunohistochemical, and molecular genetic features of three cases of testicular and four cases of ovarian mixed germ cell sex cord-stromal tumors (MGSCT).
Dvorak, Vladimir   +9 more
core   +2 more sources

Surgical salvage in patients with advanced testicular cancer: indications, risks and outcomes [PDF]

open access: yes, 2020
The purpose of this review is to present a comprehensive and updated review of the literature and summary of the indications, risks and outcomes related to salvage, desperation and late relapse surgery for advanced testicular cancer.
Cary, Clint   +2 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Fine needle aspiration cytology and cell block in the diagnosis of seminoma testis

open access: yesJournal of Cytology, 2011
Testicular neoplasms which show a wide variety of morphologic types, comprise a small proportion of malignancies. Early identification and treatment is essential for achieving long term survival.
Abhishant Pandey   +3 more
doaj   +1 more source

Feminization and severe pancytopenia caused by testicular neoplasia in a cryptorchid dog [PDF]

open access: yes, 2016
In this case report, a paraneoplastic syndrome caused by testicular neoplasia in a ten-year-old cryptorchid dog is described. Feminization and pancytopenia were observed, resulting from the testicular neoplastic production of estrogens.
Hebbelinck, Lien   +3 more
core  

Management of germ cell tumors in children: Approaches to cure [PDF]

open access: yes, 2002
The introduction of cisplatinum chemotherapy and current advances in the surgical treatment have resulted in a dramatic improvement of the prognosis of children with malignant germ cell tumors (GCT).
Calaminus, G.   +4 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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