Results 131 to 140 of about 22,224 (299)

Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli- and Leydig cells article [PDF]

, 2018
The most common human sex chromosomal disorder is Klinefelter syndrome (KS; 47,XXY). Adult patients with KS display a diverse phenotype but are nearly always infertile, due to testicular degeneration at puberty.
Aksglaede, Lise, Almstrup, Kristian, Belling, Kirstine G., Brunak, Søren, Dalgaard, Marlene Danner, Jensen, Jacob Malte, Juul, Anders, Nielsen, John Erik, Rajpert-De Meyts, Ewa, Schierup, Mikkel Heide, Skakkebæk, Niels Erik, Winge, Sofia Boeg   +11 more
core   +2 more sources

How successful is repeat testicular sperm extraction in patients with azoospermia? [PDF]

, 2006
V. Vernaeve, Greta Verheyen, A. Goossens, André Van Steirteghem, Paul Devroey, Herman Tournaye   +5 more
openalex   +1 more source

Cryptorchidism: Novel genetic insights into CCDC149 mutations

Andrology, EarlyView.
Abstract Background Cryptorchidism, characterized by the failure of one or both testes to descend into the scrotum, is a common congenital condition that can lead to infertility and increased risk of testicular cancer. CCDC149, a coiled‐coil domain‐containing protein, has been implicated in various developmental processes, but its role in the male ...
Shengrong Du, Shan Xu, Lei Yang, Yan Ye, Yuhan Wu, Ziyun Xiao, Xiuqing Dong, Wenliang Yao, Hua Li   +8 more
wiley   +1 more source

Global human tissue profiling and protein network analysis reveals distinct levels of transcriptional germline-specificity and identifies target genes for male infertility [PDF]

, 2017
BACKGROUND Mammalian spermatogenesis is a process that involves a complex expression program in both somatic and germ cells present in the male gonad.
Chalmel, Frédéric, Demougin, Philippe, Evrard, Bertrand, Feig, Caroline, Gattiker, Alexandre, Jégou, Bernard, Kirchhoff, Christiane, Lardenois, Aurélie, Mathieu, Romain, Primig, Michael, Schulze, Wolfgang   +10 more
core  

Modified cytoskeletal and extracellular matrix composition in the canine testis after long‐acting gonadotropin‐releasing hormone agonist deslorelin treatment

Andrology, EarlyView.
Abstract Background Long‐acting gonadotropin‐releasing hormone (GnRH) agonists are commonly used for fertility control in male dogs. Their effect on testicular histomorphology has not been clarified. Objectives To elucidate the mechanisms underlying androgen withdrawal in response to long‐acting GnRH agonist deslorelin 4.7 mg treatment on testicular ...
Aykut Gram, Murat Abay, Duygu Yaman Gram, Narin Liman, Linda Müller, Orsolya Balogh   +5 more
wiley   +1 more source

Laboratory processing and intracytoplasmic sperm injection using epididymal and testicular spermatozoa: what can be done to improve outcomes?

Clinics
There are two main reasons why sperm may be absent from semen. Obstructive azoospermia is the result of a blockage in the male reproductive tract; in this case, sperm are produced in the testicle but are trapped in the epididymis.
Wana Popal, Zsolt P. Nagy
doaj   +1 more source

Ultrasonographically determined size of seminiferous tubules predicts sperm retrieval by microdissection testicular sperm extraction in men with nonobstructive azoospermia

, 2020
Shoichi Nariyoshi, Kazuma Nakano, Gen Sukegawa, Takehiko Sho, Yuji Tsuji   +4 more
openalex   +1 more source

Single blastocyst transfer after ICSI from ejaculate spermatozoa, percutaneous epididymal sperm aspiration (PESA) or testicular sperm extraction (TESE) [PDF]

, 2007
Staffan Nilsson, Urban Waldenström, Ann-Britt Engström, Dan Hellberg   +3 more
openalex   +1 more source

Should a negative microsurgical testicular sperm extraction be repeated routinely? [PDF]

, 2023
Raevti Bole, Scott D. Lundy, Sarah C. Vij, Larry I. Lipshultz, John P. Lindsey, Juan R. Torres-Anguiano, Michael L. Eisenberg   +6 more
openalex   +1 more source

Mouse genome engineering uncovers 18 genes dispensable for male reproduction

Andrology, EarlyView.
Abstract Background Male infertility is an intricate multifactorial disease involving the interplay between genetic and environmental factors. Genetic anomalies account for more than 15% of all male infertility cases; however, diagnosing them exhibits enormous challenges due to variable symptomatic presentations and limited knowledge of gene functions.
Hsin‐Yi Chang, Yonggang Lu, Kaito Yamamoto, Jiang Sun, Keisuke Shimada, Yuki Hiradate, Yoshitaka Fujihara, Masahito Ikawa   +7 more
wiley   +1 more source