Results 141 to 150 of about 21,382 (249)

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

Andrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

The Challenges and Benefits of an Open Anterior Repair of Recurrent Inguinal Hernias: A Cohort Study

ANZ Journal of Surgery, EarlyView.
ABSTRACT Introduction Recurrent inguinal hernia repair presents unique clinical challenges. While minimally invasive surgery (MIS) is often preferred, open anterior mesh repair is a valid approach particularly when requiring mesh, suture, or tack removal. This study evaluates the outcomes of a small incision open anterior mesh repair, including foreign
Marie‐Alexandre Adom, Chun Tung D. Wu, Nazim Bhimani, Nicola Dodds, Anthony Glover, Thomas J. Hugh   +5 more
wiley   +1 more source

Microsurgical Testicular Sperm Extraction (MicroTESE) sperm retrieval rate (SRR) post Testicular Sperm Aspiration (TESA) [PDF]

Fertility and Sterility, 2016
A.H. AlMalki, A. Zini
openaire   +1 more source

SOX30 Governs Synaptonemal Complex Assembly and Homologous Recombination in Male Meiosis

Cell Proliferation, EarlyView.
The transcription factor SOX30 directly binds promoter regions of SYCE1 and SYCE2 to mediate their transcriptional activation, thereby enabling proper assembly of central elements within the synaptonemal complex. Structural destabilisation of the synaptonemal complex in Sox30 KK spermatocytes triggers synaptic discontinuity, impairs homologous ...
Kangle Liu, Wenfeng Zhang, Xiao Jiang, Jianping Chen, Lei Zhu, Zhonghao Zhang, Jing Gu, Lulu Guo, Lin Ao, Qing Chen, Lei Sun, Yuhan Hu, Xin Wang, Yaxin Liu, Jia Cao, Fei Han, Jinyi Liu   +16 more
wiley   +1 more source

Diagnostic yield of OCT3/4 reflex testing in testicular biopsy

Histopathology, EarlyView.
GCNIS detection frequency was 48/3353 (1.4%) testicular biopsies from 42/1870 (2.2%) men who underwent testicular biopsy with or without testicular sperm extraction (TESE). OCT3/4 was particularly helpful for detecting interstitial seminoma, GCNIS coexisting with mature spermatogenesis, and focal GCNIS.
Roselyne Choiniere, Willem PA Boellaard, Geert JLH van Leenders   +2 more
wiley   +1 more source

Laboratory processing and intracytoplasmic sperm injection using epididymal and testicular spermatozoa: what can be done to improve outcomes?

Clinics, 2013
There are two main reasons why sperm may be absent from semen. Obstructive azoospermia is the result of a blockage in the male reproductive tract; in this case, sperm are produced in the testicle but are trapped in the epididymis.
Wana Popal, Zsolt P. Nagy
doaj  

Histological characterisation of gonadal sex differentiation in Malabar red snapper (Lutjanus malabaricus) for aquaculture advancement

Journal of Fish Biology, EarlyView.
Abstract The Malabar red snapper (Lutjanus malabaricus) is a high‐value tropical marine species receiving growing attention for aquaculture development in Singapore and Southeast Asia. At present, seed production relies primarily on uncontrolled mass spawning in sea cages, a practice that lacks consistency, biosecurity and control of genetic ...
Bing Liang, Dean R. Jerry, Joyce Koh, Purushothaman Kathiresan, Celestine Terence, Xueyan Shen, Grace Loo, Shubha Vij, Jose A. Domingos   +8 more
wiley   +1 more source

Sperm cryopreservation protocol for micro-TESE-retrieved sperm

Asian Journal of Andrology
Azoospermia is characterized by the absence of sperm in the ejaculate and is categorized into obstructive azoospermia (OA) and nonobstructive azoospermia (NOA).
Vijay Mangoli, Evangelini Evgeni, Christine Wyns   +2 more
doaj   +1 more source

Testicular sperm extraction and intracytoplasmic sperm injection in non-obstructive azoospermia.

Chinese medical journal, 2002
Objective To report the experience in sperm extraction from testicular biopsies (TESE) performed from March 1996 to July 1998 in men with non-obstructive azoospermia (NOA). Methods Comparisons of age, volume of both testes, serum FSH and testosterone in men, and histology of testicular samples in the first cycles between cycles with spermatozoa found ...
Ho, PC, So, WK, Tam, PC, Ng, HYE, Lau, YL, Yeung, SB   +5 more
openaire   +2 more sources

Chronic Low‐Dose Unsymmetrical Dimethylhydrazine Exposure in Rats: Multiorgan Mechanisms and Biomarker Identification

Journal of Applied Toxicology, Volume 46, Issue 6, Page 1987-2002, June 2026.
ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu, Bing Liu, Keli Wang, Xiaoyu Wang, Zhen Sun, Xiaojuan Pan, Zengming Zhao   +6 more
wiley   +1 more source