RLIM‐associated neurodevelopmental disorders: From clinical spectrum to molecular mechanisms
RLIM (RNF12) is an E3 ubiquitin ligase essential for mammalian development. Loss‐of‐function variants cause Tønne–Kalscheuer syndrome, while duplications cause Xq13 duplication syndrome, highlighting RLIM dosage sensitivity. This review summarizes the genetics, clinical features, and molecular mechanisms of RLIM‐associated disorders, integrating ...
Madison Landon +4 more
wiley +1 more source
Clomiphene citrate and human chorionic gonadotropin treatment before microdissection testicular sperm extraction in non-obstructive azoospermia: a retrospective non-randomized series. [PDF]
Al-Zubi M +10 more
europepmc +1 more source
Stepwise mini-incision microdissection testicular sperm extraction in NOA patients with a history of cryptorchidism: a case-control study. [PDF]
Xu S +9 more
europepmc +1 more source
Understanding extracellular vesicles in antiaging
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad +3 more
wiley +1 more source
Comparison of intracytoplasmic sperm injection outcomes in men with spinal cord injury using sperm retrieved by electroejaculation and testicular sperm extraction methods: A retrospective cohort study. [PDF]
Haghdani S +3 more
europepmc +1 more source
Abstract Sedentary behaviour is increasingly recognized as a risk factor for systemic disorders; however, its effects on male reproductive health and penile tissue integrity remain insufficiently understood. Furthermore, the therapeutic role of whole‐body vibration (WBV) has not been investigated. This study evaluated the effects of sedentary behaviour
Mujdat Ayva +8 more
wiley +1 more source
Anti-Müllerian Hormone as a Biomarker for Predicting Testicular Sperm Extraction Outcomes in Azoospermic Patients: A Comprehensive Systematic Review and Meta-Analysis. [PDF]
Puia D +5 more
europepmc +1 more source
Onco-TESE (Testicular Sperm Extraction): Insights from a Tertiary Center and Comprehensive Literature Analysis. [PDF]
Cirigliano L +9 more
europepmc +1 more source
Geographical Pattern of Testicular Cancer Points to Maternal Exposures Behind Increasing Incidence
ABSTRACT Evidence suggests that testicular cancer (TC) originates from germ cell neoplasia in situ arising during fetal development, implying that prenatal environmental exposures may influence disease risk. We investigated whether maternal place of residence during pregnancy is associated with regional variation in TC incidence.
Antti Kaipia +8 more
wiley +1 more source

