Results 121 to 130 of about 642,675 (267)

Limited Clinical Impact of Androgen Receptor Repeat Length (CAG and GGC) in Klinefelter Syndrome: A Multivariable Analysis

Andrology, EarlyView.
ABSTRACT Background Klinefelter syndrome (KS) is characterized by marked phenotypic heterogeneity that might be influenced by genetic modifiers, including androgen receptor (AR) repeat length (CAGn and GGCn). The clinical relevance of these repeat lengths in patients with KS before testosterone replacement therapy (TRT) remains unclear.
Andrea Graziani, Alberto Scala, Maria Santa Rocca, Cinzia Vinanzi, Giuseppe Grande, Andrea Di Nisio, Riccardo Selice, Antonella Di Mambro, Alberto Ferlin   +8 more
wiley   +1 more source

SAVE Testis-sparing score: a multicenter retrospective study of a novel predictive tool for quantifying testicular tumors. [PDF]

Int J Surg, 2023
Liu Z, Xie J, Gao X, Lin Y, Sun M, Sun Y, Peng D, Xie H, Li X, Li Z, Cai T, Chen P, Wu Z, Guo S, Li Y, Zhang Z, Qin Z, Han H, He Z, Liu J, Fu W, Li S, Xia D, Wang X, Deng C, Xu Z, Zhou F, Yao K, Yu W, Ye Y, Liu Z.   +30 more
europepmc   +1 more source

Diacerein Disrupts Testicular Homeostasis: The Essential Role of Basal Cytokines in Maintaining Sertoli Cell Integrity and the Immune Microenvironment

Andrology, EarlyView.
ABSTRACT Background Pro‐inflammatory cytokines, TNF and IL‐1B, are essential for testicular homeostasis. Diacerein, an anti‐inflammatory drug, inhibits these cytokines, impairing M2 macrophages and Leydig cells (LCs). However, its impact on Sertoli cells (SCs) and M1 (CD68) macrophages remains unknown.
Elide Loise Freitas de Jesus, André Acácio Souza da Silva, Olumide Stephen Akinsomisoye, Erick J. R. Silva, Paulo Sérgio Cerri, Salmo Azambuja de Oliveira, Estela Sasso‐Cerri   +6 more
wiley   +1 more source

Exceedingly Rare Bilateral Synchronous Germ Cell Testicular Tumors With Different Histopathological Features. [PDF]

Cureus, 2023
Kim JH, Page RD, Moses GA, Columbres RC.
europepmc   +1 more source

A Spotlight on Yolk‐sac Tumors: Molecular Pathology, Current Diagnostics, and Novel Therapeutics

Andrology, EarlyView.
ABSTRACT Background Yolk‐sac tumors are an aggressive subtype of testicular cancer that significantly contribute to disease progression and therapy resistance, especially in adults. While testicular cancer generally has high cure rates with cisplatin‐based treatment, adult yolk‐sac tumors often appear as components of mixed tumors with poor response to
Evangelos Prokakis, Lisa Schneider, Felix Bremmer, Daniel Nettersheim   +3 more
wiley   +1 more source

Burnt out testicular tumor - A case report

Indian Journal of Pathology and Microbiology
Spontaneous regression of testicular tumors known as burnt-out tumor of testis is a rare entity and is seen in about 5% of testicular germ cell tumors.
Shri Lakshmi Surapaneni, Ramakoteswar R. Nutakki, Vandana Gangadharan, Rupa K. Gara   +3 more
doaj  

An Overview of the Role of Multiparametric MRI in the Investigation of Testicular Tumors. [PDF]

Cancers (Basel), 2022
Tsili AC, Sofikitis N, Pappa O, Bougia CK, Argyropoulou MI.   +4 more
europepmc   +1 more source

Improving the Understanding of Late Effects of Testicular Cancer in Adolescent and Young Adult Survivors: TRANSCEND‐XR

Andrology, EarlyView.
ABSTRACT Background Testicular cancer (TC) is the most common malignancy amongst adolescents and young adults (AYAs) aged 15–39 years assigned male at birth. Survivors often experience late effects of treatment and report unmet supportive care needs.
Mohamad M. Saab, Josephine Hegarty, Jack P. Gleeson, David Murphy, Sheena McHugh, Frances Shiely, Aileen Murphy, Ann Kirby, Ida J. Korfage, Sophie Terhaard, Agnes van der Heide, Johannes Sivesgaard, Matias Katajavaara Seidler, Anna Patrikidou, Davor Ježek, Lynda Corrigan, Patrice Kearney Sheehan, Daniele Raggi, Alison Reid, Michal Chovanec, Patrizia Gianntempo, Jourik A. Gietema, Justine Fleur van der Feen, Francisco Lupiáñez‐Villanueva, Ana Roca‐Umbert, Joanne Reid, Paulo Alves, Joana Soares, Karen Galvin, Michal Kubo, Maria O'Malley   +30 more
wiley   +1 more source

Malignant testicular tumors in children: A single institution's 12-year experience. [PDF]

Medicine (Baltimore), 2022
Chiu CC, Jaing TH, Lai JY, Chen SH, Chang TY, Hsueh C, Wen YC, Tsay PK.   +7 more
europepmc   +1 more source

Neoplastic Risk in Patients With Klinefelter Syndrome

Andrology, EarlyView.
ABSTRACT Background Besides gonadal involvement (hypogonadism, male factor infertility, and testicular hypotrophy), patients with Klinefelter syndrome (KS) may suffer from several extra‐gonadic complications, including neoplastic events. Objective The aim of this review is to summarize all major clinical evidence dealing with the association between KS
Andrea Graziani, Giuseppe Grande, Riccardo Selice, Antonella Di Mambro, Alberto Ferlin   +4 more
wiley   +1 more source