Results 81 to 90 of about 642,675 (267)

Prevention of Early Onset of Breast Cancer With Ashwagandha

Molecular Carcinogenesis, EarlyView.
ABSTRACT Prevention of breast cancer is feasible because many risk factors for this malignancy are known (e.g., family history, reproductive factors, etc.). Medicinal plants and/or their bioactive phytochemicals are attractive for the prevention of early onset of breast cancer due to their generally favorable safety profile.
Eun‐Ryeong Hahm, Su‐Hyeong Kim, Shivendra V. Singh   +2 more
wiley   +1 more source

Exploring the Reproductive Toxicity of Bisphenol S Through a Network Toxicology and Molecular Docking Analysis

Pediatric Discovery, EarlyView.
Utilizing network toxicology, molecular docking, and dynamic simulations to investigate the potential reproductive toxicity of bisphenol S (BPS). ABSTRACT The aim of this study was to investigate the potential reproductive toxicity of bisphenol S (BPS) and the related molecular mechanisms through a network toxicology approach.
Siyuan Wang, Yan Fu, Xu Huang, Qitong Guo, Xiangqin Zheng, Shengde Wu, Lianju Shen, Guanghui Wei   +7 more
wiley   +1 more source

Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14. [PDF]

, 2013
Testicular germ cell tumor (TGCT) is the most common cancer in young men and is notable for its high familial risks. So far, six loci associated with TGCT have been reported.
Robert A Huddart, Sheila Seal, Eeles, Rosalind, Kote-Jarai, Zsofia, Elliot, Anna, Ruark, E, McDonald, Heather, Peto, Julian, D Timothy Bishop, Muir, K; id_orcid, Stratton, Michael R, Seal, Sheila, Turnbull, Clare, Kote-Jarai, Z, Muir, Kenneth (Kenneth R.), Kenneth Muir, Perdeaux, Elizabeth, Easton, Douglas F, McDonald, H, Zhang, Feng, Easton, Douglas F., Elizabeth Rapley, Muir, K, Seal, S, Janet Shipley, Perdeaux, E, Stratton, MR, Feng Zhang, KingWai Lau, Rahman, N, Huddart, RA, Bishop, DT, Rapley, Elizabeth, Rosalind Eeles, Stratton, Michael R., Huddart, Robert A, Heather McDonald, Huddart, R A, Nazneen Rahman, Muir, Kenneth, Elise Ruark, Shipley, Janet, McDonald, H. (Heather), UK Testicular Cancer Collaboration (UKTCC), Michael R Stratton, Anna Elliot, Nsengimana, J, Eeles, R, Jeremie Nsengimana, Elliot, A, Douglas F Easton, Shipley, J, UK Testicular Cancer Collaboration (UKTCC),, Turnbull, C, Elizabeth Perdeaux, Zsofia Kote-Jarai, Rapley, E. (Elizabeth), Bishop, D. Timothy (David Timothy), Clare Turnbull, Peto, J, Stratton, M R, Lau, Kingwai, Lau, K, Nsengimana, Jeremie, Ruark, Elise, Bishop, D Timothy, Easton, DF, Zhang, F, Rahman, Nazneen, Easton, D F, Rapley, E, Julian Peto, Bishop, D T, Huddart, Robert A.   +73 more
core   +1 more source

Human Umbilical Cord Mesenchymal Stem Cell–Derived Exosomes Attenuate Renal Fibrosis by Suppressing Fibroblast Activation via the INHBA/PI3K/AKT Pathway

Pediatric Discovery, EarlyView.
MSC‐Exo derived from human umbilical cord (HucMSC‐Exo) downregulates INHBA expression, consequently modulating the PI3K/AKT signaling cascade. This regulation attenuates renal fibroblast activation and extracellular matrix deposition, thereby exerting a renoprotective effect against fibrosis.
Meiling Chen, Chenxi Jia, Zhuocheng Shi, Bianan Zhu, Yihang Yu, Xing Liu, Feng Liu, Jianwei Chen, Tao Xu, Yuanyuan Zhang, Deying Zhang, Guanghui Wei   +11 more
wiley   +1 more source

Epidermoid cyst of the testis: A report of three cases

Clinical Case Reports
Key Clinical Message Testicular epidermoid cysts have characteristic findings. Testicular tumor markers are negative in patients with epidermoid cysts.
Kimitsugu Usui, Ryo Yamashita, Yuma Sakura, Masafumi Nakamura, Hideo Shinsaka, Masato Matsuzaki, Masashi Niwakawa   +6 more
doaj   +1 more source

MicroRNA‐130a‐3p Targets the Androgen‐Related Transcription Factor MAFB: Effects on Proliferation, Migration, Apoptosis, and Cell Cycle in Hypospadias

Pediatric Discovery, EarlyView.
MicroRNA‐130a‐3p targets and inhibits MAFB expression, leading to the development of hypospadimas. MicroRNA‐130a‐3p inhibits the expression of MAFB, disrupts the normal processes of cell proliferation, migration, cell apoptosis, and cycle progression, and ultimately leads to the development of hypospadias.
Jiaxin Zhou, Yixuan Wang, Zhicheng Zhang, Qiang Zhang, Zhenmin Liu, Hongsong Chen, Xingguo Luo, Chunlan Long, Lianju Shen, Xing Liu, Guanghui Wei   +10 more
wiley   +1 more source

BILATERAL TESTICULAR TUMORS

Urology Research and Practice, 2019
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O. NAZLI, C. GİRGİN, A. Gürsan, O. Yurtseven, N. Mülazımoğlu   +4 more
doaj   +2 more sources

Testicular schistosomiasis as differential diagnosis for testicular nodules: a case report

Revista da Sociedade Brasileira de Medicina Tropical, 2015
Despite its infrequent occurrence, testicular schistosomiasis forming pseudo-tumors can be considered in the differential diagnosis of testicular tumors, especially in areas where the parasitic disease is endemic.
Tiago Neves Ferreira, Hana Caroline Morais Higa, Ronaldo Garcia Rondina, Márcio Maia Lamy Miranda, Marcos Lyra Kaddoun, Maria Carmen Ferreira Lopes Silva Santos, Rodrigo Stênio Moll de Souza   +6 more
doaj   +1 more source

Bilateral testicular germ cell tumors.

, 2015
392 Background: Germ cell tumors (GCTs), both seminomatous and non-seminomatous, account for greater than 90% of testicular cancers. While bilateral testicular GCTs are rare, the incidence of bilateral tumors has increased over time. Methods: 668 cases
Clair Beard, Laurence Albiges, Stephanie A. Curreri, Sophia C. Kamran, Alexi A. Wright, Christopher Sweeney, Rowan Miller, Elizabeth O'Donnell, Brandon David Bernard, Sarah C. Markt   +9 more
core   +1 more source

Endocrine therapy‐induced cancer‐related fatigue in hormone‐dependent malignancies: Mechanisms, impact, and management strategies

Precision Medical Sciences, EarlyView.
Multipathway schematic of endocrine therapy–induced cancer‐related fatigue. Endocrine interventions trigger four interacting mechanisms—neuroendocrine dysregulation, systemic inflammation, energy‐metabolic failure, and psycho‐behavioral amplification—that culminate in the multidimensional CRF phenotype.
Jiajing Jiang, Jun Lu, Sen Qin, Ruzhou Chen, Qiuchen Zhang, Lvqi He, Yubei Li, Jingyao Yan   +7 more
wiley   +1 more source