Results 161 to 170 of about 25,819,872 (363)
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
USE OF INTERNATIONAL DOCUMENTS FOR QUALITY CONTROL OF EDUCATIONAL ASSESSMENT IN UKRAINE
The article is devoted to quality assurance of educational assessment – international approaches and prospects for use of international recommendations at the current stage of development of educational assessment in Ukraine.
Iryna Ye. Bulakh, Maryna R. Mrouga
doaj
Cycling performance is strongly influenced by aerodynamics, with most resistive drag forces being attributed to the rider. The Body Rocket device (BR) is an on‐bike sensor system that uses the same load cell technology as a wind tunnel, directly ...
James G. Hopker +3 more
doaj +1 more source
Random effects structure for confirmatory hypothesis testing: Keep it maximal.
D. Barr +3 more
semanticscholar +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
THE CONTROL OF THE FALSE DISCOVERY RATE IN MULTIPLE TESTING UNDER DEPENDENCY
Y. Benjamini, D. Yekutieli
semanticscholar +1 more source
Differential susceptibility to parenting among African American youths: Testing the DRD4 hypothesis.
Steven R. H. Beach +3 more
openalex +2 more sources
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source

