Results 191 to 200 of about 25,819,872 (363)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

TESTING FOR PHYLOGENETIC SIGNAL IN COMPARATIVE DATA: BEHAVIORAL TRAITS ARE MORE LABILE

Evolution; international journal of organic evolution, 2003
S. Blomberg, T. Garland, A. Ives
semanticscholar   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

The FDA's plan to phase out animal testing. [PDF]

Trends Biotechnol
Gerke S, Balamut J, Wagner JK.
europepmc   +1 more source

Multilaboratory Testing of Antifungal Combinations against a Quality Control Isolate of Candida krusei

, 2008
Vishnu Chaturvedi, Rama Ramani, Mahmoud A. Ghannoum, S. B. Killian, Nicole Holliday, Cindy C. Knapp, Luis Ostrosky‐Zeichner, S. A. Messer, Michael A. Pfaller, Naureen Iqbal, Beth A. Arthington‐Skaggs, José A. Vázquez, Tin Sein, John Rex, Thomas J. Walsh   +14 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Associated factors of HIV testing behaviours among sexual partners/spouses between young and middle-aged/older people living with HIV in China: a cross-sectional study. [PDF]

BMJ Public Health
Shi Y, Han S, Ming J, Zhang C, Chen W, Zhang L, Wu B, Chen S, Chen H, Wang F, He Y.   +10 more
europepmc   +1 more source

Testing for Error Correction in Panel Data

, 2006
J. Westerlund
semanticscholar   +1 more source

Community Mobilization for HIV Testing Uptake: Results From a Community Randomized Trial of a Theory-Based Intervention in Rural South Africa

, 2016
Sheri A. Lippman, Torsten B. Neilands, Catherine MacPhail, Dean Peacock, Suzanne Maman, Dumisani Rebombo, Rhian Twine, Amanda Selin, Hannah H. Leslie, Kathleen Kahn, Audrey Pettifor   +10 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source