Results 241 to 250 of about 5,053,017 (341)

Opportunities to Optimize Outcomes of Diagnosis and Treatment of HIV and Syphilis in Pregnancy: the Quest to Eliminate Maternal and Vertical Transmission. [PDF]

Curr HIV/AIDS Rep
Joseph Davey D, de Voux A, Shaetonhodi N, Marks M, Frigati L, Kufa T.   +5 more
europepmc   +1 more source

Germline variants in CDKN2A wild‐type melanoma prone families

Molecular Oncology, EarlyView.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen, Marie Loeng, Amalie Lund Holth, Per E. Lønning, Jürgen Geisler, Stian Knappskog   +5 more
wiley   +1 more source

Perioperative Anaphylaxis: A Systematic Approach to Evaluate High-Risk Drug Allergy. [PDF]

Case Rep Crit Care
Navard-Keck A, Gabryszewski SJ, Robbins ES, Cafone J, Lee J.   +4 more
europepmc   +1 more source

Further Tests for Tumour-Initiating Activity: N,N-DI-(2-Chloroethyl)-P-Aminophenylbutyric Acid (CB1348) as an Initiator of Skin Tumour Formation in the Mouse

, 1956
M. H. Salaman, F. J. C. Roe
openalex   +2 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

ProstaNet: A Novel Geometric Vector Perceptrons-Graph Neural Network Algorithm for Protein Stability Prediction in Single- and Multiple-Point Mutations with Experimental Validation. [PDF]

Research (Wash D C)
Liang T, Sun ZY, Ishima R, Xie XQ, Xue Y, Li W, Feng Z.   +6 more
europepmc   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Claim Denials for Cancer-Related Next-Generation Sequencing in Medicare.

JAMA Netw Open
Kang SY, Odouard I, Gresenz CR.
europepmc   +1 more source

From Lab to Field: Damp Heat Testing and its Implications for PV Module Service Lifetime. [PDF]

Glob Chall
Gok A.
europepmc   +1 more source

The Effect of Orally Administered Molybdenum on Growth, Spermatogenesis and Testes Histology of Young Dairy Bulls

, 1951
James W. Thomas, Samuel Moss
openalex   +1 more source