Results 91 to 100 of about 3,400,893 (302)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Background The fish microbiome is increasingly recognized as an important factor influencing host responses to xenobiotics, although its role remains largely associative and is still being elucidated.
Kampan Bisai +4 more
doaj +1 more source
Cost of running a full-service receiving office at a centralised testing laboratory in South Africa. [PDF]
Cassim N +3 more
europepmc +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Investigation of Alternative Deicers for Snow and Ice Control [PDF]
This technical report presents the findings of the laboratory analysis of potassium succinate (KSu) as a roadway deicer. Laboratory analysis included modified SHRP ice-melting testing, a differential scanning calorimetry (DSC) thermogram, and friction ...
Akin, Michelle, Fay, Laura
core
Construction Products between Testing Laboratory and Market Surveillance: Case study of Cementitious Ceramic Tile Adhesives. [PDF]
Stancu C, Dębski D, Michalak J.
europepmc +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Elastomer Compound Developed for High Wear Applications [PDF]
The U.S. Army is currently spending 300 million dollars per year replacing rubber track pads. An experimental rubber compound has been developed which exhibits 2 to 3 times greater service life than standard production pad compounds.
Crawford, D. +5 more
core +1 more source

