Results 151 to 160 of about 5,262,635 (292)

A Narrative Review of Early Pregnancy Diagnosis Technologies for Livestock: From Conventional to Intelligent Systems. [PDF]

Animals (Basel)
Shen Y, Zhang Y, Meng J, Han Y, Xu J, Wang H, Wang L.   +6 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Mechanical Performance of 3D-Printed Resin Materials for Endocrown Restorations: A Comparative Evaluation of Fracture Resistance, Weibull Analysis, and Experimental Fracture Toughness. [PDF]

J Funct Biomater
Abuabboud O, Marinescu AG, Paven M, Kovacs IM, Nica LM, Faur AB, Marșavina L, Stoia DI, Jivănescu A.   +8 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Suppressing artifacts and quantitative evaluation of internal defects in laser ultrasonic multi-mode time-domain synthetic aperture focusing technique via mode separation. [PDF]

Photoacoustics
Zeng W, Chen H, Zhu W.
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

The causal relationship between antibody-mediated immune responses to infections and Graves' disease: a bi-directional Mendelian randomization analysis. [PDF]

Exp Biol Med (Maywood)
Zhang X, Xu W, Liu Z, Zhang J, Yang X.
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Foreign markets entry mode decision for SMEs. Key factors and role of industrial districts. [PDF]

The principal aim of this paper was to examine the internationalization of small and medium-sized enterprises (SMEs) in regard to the entry mode selection process.
Francioni, Barbara, Musso, Fabio
core  

Distinct Bone Marrow Metabolic Profiles at Relapse Compared with Initial Diagnosis in Pediatric Acute Lymphoblastic Leukemia-An LC-MS Metabolomics Study. [PDF]

Cancers (Basel)
Dissook S, Kittichaiworakul R, Thongkumkoon P, Noisagul P, Fanhchaksai K, Sathitsamitphong L, Choed-Amphai C, Charoenkwan P, Chaiyawat P, Sangphukieo A, Natesirinilkul R.   +10 more
europepmc   +1 more source