Results 141 to 150 of about 279,657 (361)
TRiC Is a Structural Component of Mammalian Sperm Axonemes
Cytoskeleton, EarlyView.ABSTRACT The TRiC chaperonin is responsible for folding ~5%–10% of the proteome in eukaryotic cells. Our recent cryo‐electron microscopy studies of axonemes from diverse mammalian cell types led to the surprising discovery that a fully assembled TRiC chaperonin is a structural component of mammalian sperm flagella, where it is tethered to the radial ...
Alan Brown +3 more
wiley +1 more source
A Lecture on the Value of the Imperfectly-Descended Testis, the Advisability of Operation, and the Value of the Operations Performed for its Relief: A Post-graduate Lecture delivered at the Hospital for Sick Children, Great Ormond Street [PDF]
, 1904 Emily Corner
openalex +1 more source
Phosphorylation at the Helm: Kinase‐Mediated Regulation of Primary Cilia Assembly and Disassembly
Cytoskeleton, EarlyView.ABSTRACT The primary cilium serves as an antenna of most vertebrate cells and is important for conveying cues from several signaling pathways into appropriate cellular responses during development and homeostasis. Cilia assembly and disassembly processes are thought to be strictly controlled; however, the precise nature of molecular events underlying ...
Andrea Lacigová, Lukáš Čajánek
wiley +1 more source
β-Glucuronidase, Lipase and Esterase in the Testis of the Cryptorchid Rat [PDF]
, 1958 Masando Hayashi +3 more
openalex +1 more source
Cytoskeleton, EarlyView.ABSTRACT Elastic tethers connect telomeres of separating chromosomes in anaphase of animal cells. Immunofluorescence staining of titin in crane‐fly spermatocytes, using 4 different antibodies, shows that the giant elastic protein titin seems to be a component of mitotic tethers: titin “strands” extend between separating chromosomes, connecting their ...
Demetra Economopoulos +5 more
wiley +1 more source
ChemMedChem, EarlyView.Herein, X‐ray structure‐based design, synthesis, and evaluation of a series of potent and selective small molecules G protein‐coupled receptor kinase 5 (GRK5) and GRK6 inhibitors that exhibit high selectivity against GRK2 are reported. A high‐resolution X‐ray crystal structure of GRK5 and inhibitor 6t complex provides important molecular insight for ...
Arun K. Ghosh +5 more
wiley +1 more source