Results 231 to 240 of about 185,233 (313)

Impact of COVID-19 on testicular torsion: A single-center retrospective study from a children's hospital. [PDF]

Investig Clin Urol
Fujimoto K, Rho BY, Lee SW, Baek JO, Lee YS, Kim SW.   +5 more
europepmc   +1 more source

Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders

Andrology, EarlyView.
Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret, Aaran H. Patel, Elisabeth Daniels, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source

Tissue-specific CLOCK isoforms modulate circadian feedback loops to govern reproductive fitness in Drosophila. [PDF]

Cell Mol Life Sci
Wang Y, Lv P, Li Y, Yang X, Du J.
europepmc   +1 more source

Luteinizing hormone receptor knockout mouse: What has it taught us?

Andrology, EarlyView.
Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
wiley   +1 more source

Prenatal Low Testosterone Levels Induced by <i>DNAH8</i> Dysfunction Leads to Urethral Fusion and Male Differentiation Abnormalities. [PDF]

Biomedicines
Peng Z, Li Y, Wang Y, Yu M, Lyu Y, Chen F, Huang Y, Ding Y.   +7 more
europepmc   +1 more source

The use of deidentified organ donor testes for research

Andrology, EarlyView.
Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova, Marnie W. Skinner, Juliana I. Candelaria, Stephen R. Wellard, Philip W. Jordan   +4 more
wiley   +1 more source

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

Andrology, EarlyView.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre, Ross C. Anderson, Teresa Zariñán, Rubén Gutiérrez‐Sagal, Eduardo Jardón‐Valadez, Claire L. Newton   +5 more
wiley   +1 more source

Extracellular-vesicle-mediated transfer of let-7b/7c promotes the proliferation of transition-state spermatogonia in neonatal mouse testis. [PDF]

Stem Cell Reports
Zheng T, Choy KHK, Chan SY, Zheng M, Luo X, Chen H, Xie T, Fok EKL.   +7 more
europepmc   +1 more source

BRD9 inhibition as potential treatment option for testicular germ cell tumors

Andrology, EarlyView.
Abstract Background Testicular germ cell tumors (TGCT) are the predominant tumor in younger males. Usually, 5‐year survival rates are quite high, but 15–20% of patients with metastatic non‐seminomas are resistant to standard cisplatin‐based therapy.
Aylin Hansen, Christine Sanders, Florian Fronhoffs, Kai Funke, Glen Kristiansen, Hubert Schorle   +5 more
wiley   +1 more source

Case Report: Bilateral testicular teratoma in an infant with torsion of an intra-abdominal testis and contralateral testicular teratoma. [PDF]

Front Pediatr
Hua C, Fan H, Guo Z, Li X, Yang Y, Bi J.
europepmc   +1 more source