Results 81 to 90 of about 256,296 (370)

Cause and consequence of cancer/testis antigen activation in cancer.

open access: yesAnnual Review of Pharmacology and Toxicology, 2014
Tumor cells frequently exhibit widespread epigenetic aberrations that significantly alter the repertoire of expressed proteins. In particular, it has been known for nearly 25 years that tumors frequently reactivate genes whose expression is typically ...
Angelique W. Whitehurst
semanticscholar   +1 more source

Revealing the Transcriptional and Metabolic Characteristics of Sebocytes Based on the Donkey Cell Transcriptome Atlas

open access: yesAdvanced Science, EarlyView.
In this study, a comprehensive single‐cell transcriptome atlas of the Dezhou donkey, encompassing 20 tissues and 275 050 cells, is constructed. Through cross‐species and cross‐tissue analyses, distinct transcriptional patterns in donkey sebocytes are identified.
Yu Tian   +11 more
wiley   +1 more source

Molecular and cellular paradigms of multidrug resistance in cancer

open access: yesCancer Reports, Volume 5, Issue 12, December 2022., 2022
Abstract Background The acquisition of resistance to chemotherapy is a major hurdle in the successful application of cancer therapy. Several anticancer approaches, including chemotherapies, radiotherapy, surgery and targeted therapies are being employed for the treatment of cancer.
Foram U. Vaidya   +6 more
wiley   +1 more source

Triorchidism: presenting as undescended testis in a case of indirect inguinal hernia

open access: yesClinics and Practice, 2016
Triorchidism is the commonest variety of polyorchidism, an entity with more than two testis is an extremely rare congenital anomaly of the testis. Although excision of the abnormal testis is a safer alternative proposed, recent literature suggests more ...
Ajay H. Bhandarwar   +5 more
doaj   +1 more source

DAPK3 is Essential for DBP‐Induced Autophagy of Mouse Leydig Cells

open access: yesAdvanced Science, EarlyView.
This study has confirmed that death‐associated protein kinase 3 (DAPK3) is essential for dibutyl phthalate (DBP)‐induced autophagy of mouse Leydig cells, and is regulated by both transcription factor specific protein 2 (Sp2) and parkin RBR E3 ubiquitin‐protein ligase (PRKN), and melatonin can alleviate DBP‐induced autophagy of the cells.
Si Yang   +4 more
wiley   +1 more source

PENGARUH PEMBERIAN BORAKS PERORAL SUB AKUT TERHADAP TERJADINYA ATROFI TESTIS TIKUS PUTIH JANTAN (RATTUS NOVERGICUS STRAIN WISTAR)

open access: yesSaintika Medika, 2017
Pengaruh Pemberian Boraks Peroral Sub Akut Terhadap Terjadinya Atrofi Testis Tikus Putih Jantan (Rattus novergicus strain wistar). Latar Belakang: Penggunaan boraks banyak disalahgunakan pada makanan.
Diana Mayasari, Nanang Mardiroharjo
doaj   +1 more source

The human testis-specific proteome defined by transcriptomics and antibody-based profiling.

open access: yesMolecular human reproduction, 2014
The testis' function is to produce haploid germ cells necessary for reproduction. Here we have combined a genome-wide transcriptomics analysis with immunohistochemistry-based protein profiling to characterize the molecular components of the testis.
Dijana Djureinovic   +10 more
semanticscholar   +1 more source

Sperm‐Derived CircRNA‐1572 Regulates Embryogenesis and Zygotic Genome Activation by Targeting CCNB2 via Bta‐miR‐2478‐L‐2

open access: yesAdvanced Science, EarlyView.
Sperm‐derived circRNA‐1572 competitively binds to bta‐miR‐2478‐L‐2 through a “sponge” mechanism to regulate cyclin B2 (CCNB2) expression, thereby modulating the distribution of fibrous actin (F‐actin) in early pig embryos, ensuring proper chromosome segregation during mitosis, and facilitating normal embryo cleavage and zygotic genome activation.
Yanfang Wu   +10 more
wiley   +1 more source

EFEK ANTIMIKROBA EKSTRAK RIMPANG KUNYIT (CURCUMA DOMESTICA) TERHADAP ESCHERICHIA COLI SECARA IN VITRO

open access: yesSaintika Medika, 2017
Pengaruh Pemberian Boraks Peroral Sub Akut Terhadap Terjadinya Atrofi Testis Tikus Putih Jantan (Rattus novergicus strain wistar). Latar Belakang: Penggunaan boraks banyak disalahgunakan pada makanan.
Resa Putra Adiputra   +2 more
doaj   +1 more source

Detection of the thermal radio continuum emission from the G9.62+0.19-F Hot Core [PDF]

open access: yesarXiv, 2000
We present new high resolution and high sensitivity multi-frequency VLA radio continuum observations of the G9.62+0.19-F hot molecular core. We detect for the first time faint centimetric radio continuum emission at the position of the core. The centimetric continuum spectrum of the source is consistent with thermal emission from ionised gas.
arxiv  

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