Results 151 to 160 of about 223,762 (305)

Low‐Dose Chlorothalonil Induces Testicular Injury Through Disruption of Steroidogenic Signaling in Adult Male Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Chlorothalonil (CHL) is a widely used organochlorine fungicide frequently detected in environmental and food matrices. Although increasing evidence indicates adverse effects in nontarget species, the mechanisms underlying CHL‐induced male reproductive toxicity remain incompletely understood.
Cristiana Livramento Oliveira Pinto, Nicoly Caixêta Gonçalves, Paula Rafaela Queiroz da Silva, Ludmila Rodrigues Pontes, Juliana Reis Machado, Virmondes Rodrigues Jr., Hugo Felix Perini, Gláucia Eloisa Munhoz de Lion Siervo   +7 more
wiley   +1 more source

Potential Neuroendocrine Disruption by Benzodiazepines and Its Impact on Male Fertility

Journal of Applied Toxicology, EarlyView.
ABSTRACT Neuroactive substances have emerged as potent endocrine disruptors affecting male reproductive health through central and peripheral mechanisms. Among these, benzodiazepines, which are widely used for the management of anxiety, insomnia, epilepsy, and neuromuscular disorders, are known as GABA A (gamma‐aminobutyric acid type A) receptor ...
Ana Clara Melo Andrade de Rodrigues, Julia Gonçalves Rodrigues, Marcos de Lucca Moreira Gomes, Fernanda Carolina Ribeiro Dias   +3 more
wiley   +1 more source

Analysis of Notch1 and Notch3 Signaling Pathway Components in Benign Prostatic Hyperplasia and Prostate Cancer Patients

Journal of Clinical Laboratory Analysis, EarlyView.
This study evaluates the association between Notch1 and Notch3 genetic variations and serum protein levels in patients with benign prostatic hyperplasia and prostate cancer. While genetic variations showed no significant link to disease risk, serum protein levels were significantly lower in prostate cancer and metastatic groups compared to healthy ...
Emine Yagci, Cansu Ozbayer, Ata Ozen, Gamze Zengin, Hulyam Kurt   +4 more
wiley   +1 more source

Testosterone depot injection in male hypogonadism: a critical appraisal

Clinical Interventions in Aging, 2008
Aksam A Yassin1, Mohamed Haffejee21Clinic of Urology/Andrology, Segeberger Kliniken, Norderstedt-Hamburg, Germany and Department of Urology, Gulf Medical College School of Medicine, Ajman-UAE 2Urology Division at the University of Witwaterstrand & ...
Aksam A Yassin, Mohamed Haffejee
doaj  

Childhood adversity and psychotic‐like experiences in adolescence: Investigating a pathway via disrupted pubertal and grey matter development

JCPP Advances, EarlyView.
Abstract Background Childhood adversity increases psychosis risk, but the biological mechanisms responsible remain elusive. A possible but underexplored pathway involves altered pubertal and grey matter (GM) development. Methods In youth from the Adolescent Brain Cognitive Development study (N = 3462), we investigated the effect of adversity at age 9 ...
Megan Thomas, Sarah Whittle, Elizabeth M. Haris, Vanessa L. Cropley   +3 more
wiley   +1 more source

Feline testosterone assay: analytical and clinical validation in intact and castrated tom cats

embargoed_20280227Introduction- Testosterone measurement plays a crucial role in differentiating intact from neutered male cats. However, reliable cut-off values and validated analytical methodologies for feline testosterone quantification remain limited.
PIMAZZONI, LAURA
core  

Adaptive Immunity in Marsupials

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
Comparison of the marsupial and eutherian adaptive immune systems. ABSTRACT Marsupials diverged from eutherian mammals 125–160 million years ago. Although evolutionarily distinct, both groups of mammals can produce complex adaptive immune responses to antigens with several key differences.
Cassandra L. Jol, Hayley J. Stannard, Julie M. Old   +2 more
wiley   +1 more source

Clinical progress note: Mumps

Journal of Hospital Medicine, EarlyView.
Abstract Mumps was a common childhood viral illness before the implementation of the measles, mumps, and rubella (MMR) vaccination in 1967. There was a significant decrease in mumps cases in the postvaccine era; however, there has been an increase in outbreaks in the United States over the past two decades.
Sarah Ludvigsen, Mati Segev
wiley   +1 more source

The association between sociodemographic and clinical factors and outcomes among inpatients with community‐acquired pneumonia

Journal of Hospital Medicine, EarlyView.
Abstract Background Community‐acquired pneumonia (CAP) is a leading cause of hospitalization and mortality. The influence of sociodemographic characteristics on adverse outcomes in adults hospitalized with CAP remains poorly understood, particularly for patients younger than 65.
Farhana Islam, Surain B. Roberts, Sarah L. Malecki, Anne Loffler, Leo Hersi, Anthony D. Bai, Amol A. Verma, Fahad Razak, Peter J. Gill, Sanjay Mahant   +9 more
wiley   +1 more source

Association of periodontitis with incidence of metabolic syndrome in Korea: A retrospective cohort study

Journal of Periodontology, EarlyView.
Abstract Background Although periodontitis has been linked to systemic conditions such as metabolic syndrome, longitudinal evidence remains limited. This nationwide population‐based cohort study aimed to investigate whether periodontal status is associated with the incidence of metabolic syndrome in Korea.
SeoYeon Hwang, Hae‐Young Kim, Sangwook Kang, Junesun Kim, Sunmi Song, Gum‐Ryeong Park   +5 more
wiley   +1 more source