Results 181 to 190 of about 223,762 (305)

Role of testosterone in regulating skeletal muscle mitochondrial homeostasis

open access: yes
openIl testosterone è un ormone steroideo noto per il suo ruolo di regolatore del trofismo muscolare ed è stato identificato come modulatore positivo dell’uniporto mitocondriale del calcio (MCU), canale responsabile del trasporto del Ca2+ all’interno ...
BOZZO, ELENA
core  

Testosterone-related indices and adverse glucose-lipid metabolic status in men: a single-center retrospective study. [PDF]

open access: yesFront Endocrinol (Lausanne)
Ma M   +8 more
europepmc   +1 more source

Endocrine therapy‐induced cancer‐related fatigue in hormone‐dependent malignancies: Mechanisms, impact, and management strategies

open access: yesPrecision Medical Sciences, EarlyView.
Multipathway schematic of endocrine therapy–induced cancer‐related fatigue. Endocrine interventions trigger four interacting mechanisms—neuroendocrine dysregulation, systemic inflammation, energy‐metabolic failure, and psycho‐behavioral amplification—that culminate in the multidimensional CRF phenotype.
Jiajing Jiang   +7 more
wiley   +1 more source

Theoretical Analysis of Androstenone Adsorption on Chimpanzee and Gorilla Olfactory Receptors (G‐Protein): Statistical Physics Modeling, Molecular Docking Simulation, and Thermodynamic Investigation

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT An advanced theory based on statistical physics was applied to microscopically investigate androstenone adsorption and its relationship with olfactory perception in chimpanzees and gorillas. For this purpose, dose–response curves of androstenone on olfactory receptors of chimpanzee OR7D4 and gorilla OR7D4 were analyzed by statistical physics ...
Ismahene Ben Khemis   +8 more
wiley   +1 more source

Development of a physiologically‐based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady‐state conditions

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 523-539, March 2025.
Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo   +5 more
wiley   +1 more source

Bisphenols and Phthalates in Bottled Mineral Water: First Evidence of Co‐Occurrence, Estrogenic Activity, and Health Risk in Brazil

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA), its structural analogs, and phthalates are synthetic chemicals widely used, with documented endocrine‐disrupting activity. This study aimed to develop and validate a selective multiresidue analytical method for the simultaneous determination of BPA, 10 bisphenol analogs, and six phthalates in PET‐bottled mineral water.
Giulia Boito Reyes   +3 more
wiley   +1 more source

Hormonal profiles of men with highly elevated SHBG and primary testicular dysfunction support free hormone hypothesis. [PDF]

open access: yesJ Endocr Soc
Gagliano-Jucá T   +11 more
europepmc   +1 more source

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