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Role of intestinal testosterone-degrading bacteria and 3/17β-HSD in the pathogenesis of testosterone deficiency-induced hyperlipidemia in males [PDF]

open access: yesnpj Biofilms and Microbiomes
Testosterone deficiency can cause abnormal lipid metabolism in men, leading to hyperlipidemia. We identified the testosterone-degrading bacterium Pseudomonas nitroreducens in the fecal samples of male patients with hyperlipidemia.
Jun Tao   +9 more
doaj   +4 more sources

Association between the weight-adjusted-waist index and testosterone deficiency in adult males: a cross-sectional study [PDF]

open access: yesScientific Reports
Testosterone deficiency has been recognized as a significant health concern and is closely related to obesity. The weight-adjusted-waist index (WWI) is an innovative adiposity parameter that is superior to BMI in certain aspects, but its relationship ...
Peiqing Wang   +9 more
doaj   +4 more sources

Testosterone Deficiency Promotes Hypercholesteremia and Attenuates Cholesterol Liver Uptake via AR/PCSK9/LDLR Pathways

open access: yesInternational Journal of Endocrinology, 2022
Background. Testosterone deficiency is reportedly correlated with an elevation of cholesterol in plasma, but the mechanism remains unclear. Our objective was to investigate the effects of testosterone deficiency on cholesterol metabolism and the ...
Yu Yuefeng   +11 more
doaj   +2 more sources

Testosterone deficiency impairs cardiac interfibrillar mitochondrial function and myocardial contractility while inducing oxidative stress

open access: yesFrontiers in Endocrinology, 2023
IntroductionClinical studies have shown that low levels of endogenous testosterone are associated with cardiovascular diseases. Considering the intimate connection between oxidative metabolism and myocardial contractility, we determined the effects of ...
Patrícia Ribeiro do Val Lima   +9 more
doaj   +2 more sources

Recommendations on the diagnosis, treatment and monitoring of testosterone deficiency in men

open access: yesAging Male, 2021
The relative proportional increase of the elderly population within many countries will become one of the most significant social transformations of the twenty-first century and, for the first time in history, persons aged 65 or above outnumbered ...
Abraham Morgentaler   +2 more
exaly   +2 more sources

Association between the oxidative balance score and testosterone deficiency in males: a cross-sectional study [PDF]

open access: yesFrontiers in Nutrition
BackgroundTestosterone deficiency is a prevalent condition among males and warrants greater attention. The balance between oxidative and antioxidant capacity plays a critical role in testosterone deficiency.MethodsThis study conducted a secondary ...
Ze Zhuge   +4 more
doaj   +2 more sources

Unmasking Masculinity: Biological, Behavioral, and Social Determinants of Testosterone Deficiency in U.S. Men, 2011–2023 [PDF]

open access: yesAmerican Journal of Men's Health
Testosterone deficiency in men is often attributed to aging or biology, yet hormone levels also reflect social determinants of health (SoDH) and masculinity-related stressors.
Andrew J. Goulian   +2 more
doaj   +2 more sources

Testosterone deficiency and chronic kidney disease. [PDF]

open access: yesJ Clin Transl Endocrinol
Testosterone’s biological functions are extensive, influencing reproductive and systemic health. It plays a vital role in sexual functions, muscle protein synthesis, bone metabolism, fat distribution, and cardiovascular health.
Zitzmann M.
europepmc   +2 more sources

Correlation between pan immune inflammation value and testosterone deficiency risk increase [PDF]

open access: yesScientific Reports
Testosterone deficiency seriously affects male reproductive function, growth and development, and quality of life. There is a certain association between inflammation and testosterone. PIV, a novel immune-inflammatory biomarker, has emerged.
Ling Tong, Gang Chen
doaj   +2 more sources

The Impact of the SMOTE Method on Machine Learning and Ensemble Learning Performance Results in Addressing Class Imbalance in Data Used for Predicting Total Testosterone Deficiency in Type 2 Diabetes Patients. [PDF]

open access: yesDiagnostics (Basel)
Background and Objective: Diabetes Mellitus is a long-term, multifaceted metabolic condition that necessitates ongoing medical management. Hypogonadism is a syndrome that is a clinical and/or biochemical indicator of testosterone deficiency.
Kivrak M, Avci U, Uzun H, Ardic C.
europepmc   +2 more sources

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