Testosterone Deficiency and Testosterone Treatment in Older Men [PDF]
Gerontology, 2016 Frailty is a clinical condition related to changes in metabolism, to sarcopenia, and to decline in muscle mass and strength, bone mineral density, and physical function with aging. The pathophysiology of frailty is multifactorial and associated with comorbidities.
Saad, Farid +3 more
openaire +5 more sources
Inverse association between serum bilirubin level and testosterone deficiency in middle-aged and older men [PDF]
Scientific Reports, 2021 Low serum bilirubin levels have been associated with increased risk of cardiovascular disease (CVD) and metabolic syndrome. Testosterone deficiency could also contribute to increased risk of CVD and metabolic syndrome.
Hye-Min Park +3 more
doaj +2 more sources
Testosterone therapy in men with testosterone deficiency: Are we beyond the point of no return? [PDF]
Investigative and Clinical Urology, 2016 Although testosterone therapy in men with testosterone deficiency was introduced in the early 1940s, utilization of this effective treatment approach in hypogonadal men is met with considerable skepticism and resistance.
Abdulmaged Traish
doaj +3 more sources
Testosterone Deficiency Promotes Hypercholesteremia and Attenuates Cholesterol Liver Uptake via AR/PCSK9/LDLR Pathways [PDF]
International Journal of Endocrinology, 2022 Background. Testosterone deficiency is reportedly correlated with an elevation of cholesterol in plasma, but the mechanism remains unclear. Our objective was to investigate the effects of testosterone deficiency on cholesterol metabolism and the ...
Yu Yuefeng +11 more
doaj +2 more sources
The Relationship between Selected Bioelements and Depressiveness Associated with Testosterone Deficiency Syndrome in Aging Men [PDF]
Medicina, 2020 Background and Objectives: Abnormal concentrations of bioelements (magnesium, manganese, chromium, copper, zinc) have been associated with physical and emotional dysfunctions, including depression.
Iwona Rotter +7 more
doaj +2 more sources
Testosterone Deficiency, Weakness, and Multimorbidity in Men [PDF]
Scientific Reports, 2018 AbstractThe purposes of this study were to evaluate the association between total testosterone (TT) deficiency and weakness on multimorbidity in men. Analyses were performed to examine the prevalence of multimobidity among young, middle-aged, and older men, with and without testosterone deficiency.
Mark D. Peterson +3 more
openaire +4 more sources
Testosterone deficiency in dialysis patients: Differences according to the dialysis techniques [PDF]
Nefrología (English Edition), 2017 Testosterone deficiency is a prevalent condition in male patients with chronic kidney disease. However, it is not known whether the type of renal replacement therapy has an impact on testosterone deficiency that accompanies loss of renal function ...
Secundino Cigarrán +7 more
doaj +2 more sources
Testosterone Deficiency, Cardiac Health, and Older Men [PDF]
International Journal of Endocrinology, 2014 Low levels of testosterone are manifested by erectile dysfunction, reduced sexual desire, and loss of morning erections with increasing numbers of men are being diagnosed and require treatment.
G. Hackett, M. Kirby, A. J. Sinclair
doaj +2 more sources
Diagnosis and management of testosterone deficiency [PDF]
Asian Journal of Andrology, 2015 Testosterone supplementation therapy (TST) use has dramatically increased over the past decade, due to the availability of newer agents, aggressive marketing, and an increasing incidence of testosterone deficiency (TD). Despite the increase in TST, a degree of ambiguity remains as to the exact diagnostic criteria of TD, and administration and ...
James A McBride +2 more
openaire +5 more sources
Mechanism of testosterone deficiency in the transgenic sickle cell mouse. [PDF]
PLoS ONE, 2015 Testosterone deficiency is associated with sickle cell disease (SCD), but its underlying mechanism is not known. We investigated the possible occurrence and mechanism of testosterone deficiency in a mouse model of human SCD.
Biljana Musicki +5 more
doaj +2 more sources