Results 1 to 10 of about 13,419 (307)

Severe Irritant Contact Dermatitis Causing Skin Ulceration Secondary to a Testosterone Patch [PDF]

The Scientific World Journal, 2009
Testosterone replacement has undergone somewhat of a revolution in the past decade with the introduction of topical administration techniques, including patches and gels, as well as an increasing interest in the treatment of older men with low ...
Nathan Lawrentschuk, Neil Fleshner
doaj   +8 more sources

A Comparison of a Novel Testosterone Bioadhesive Buccal System, Striant, with a Testosterone Adhesive Patch in Hypogonadal Males [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2004
A novel delivery system has been developed for testosterone replacement. This formulation, COL-1621 (Striant), a testosterone-containing buccal mucoadhesive system, has been shown in preliminary studies to replace testosterone at physiological levels when used twice daily.
Márta Korbonits, Marc Slawik, D. R. Cullen, Richard Ross, Günter K. Stalla, Harald Schneider, Martín Reincke, Pierre Bouloux, Ashley Grossman   +8 more
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FDA panel rejects testosterone patch for women on safety grounds [PDF]

BMJ, 2004
A panel of advisers to the US Food and Drug Administration last week unanimously rejected an experimental testosterone patch as a treatment for women with sexual difficulties. Procter & Gamble, global manufacturer of household products, wants to market the patch to women who have become menopausal after ovarian surgery, are currently taking oestrogen,
Ray Moynihan
openalex   +3 more sources

Local and Systemic Complications of Local Testosterone Patches and Gels

Journal of Pharmaceutical Research International, 2021
In recent decades, testosterone therapy has gained the attention of many researchers due to the increased demand for this modality worldwide, the increased average age of the different populations, and increased awareness of the potential uses of the modality in clinical settings.
Fahad Ahmed Al-Zahrani, Areej Ibrahim Aziaby, Mohammed A. Alkhalifah, Abdalkarim Ahmed Alalsheikhahmed, Rawa Mohammed Aldosari, Mohammed Khamis Albalawi, Mohammad Almohammadi, Alaa Alzahrani, Ghassan Mohammedzaki Damanhori, Eman Abdulaziz Alaswami, Mohammed Khaled Almutairy   +10 more
openalex   +3 more sources

Clinical Electrophysiology and Mathematical Modeling for Precision Diagnosis of Infertility [PDF]

Biomedicines
How can cellular electrophysiology measurements and mathematical modeling of ionic channels help to identify pivotal targets in disease-related cell signaling?
Fernanda Carvalho Cavalari, Paola Sulis Mendes, Bruna Antunes Zaniboni, Carine Royer, Bárbara Ogliari Martins Taques, Karina Cesca, Marcela Aragón, Fátima Regina Mena Barreto Silva   +7 more
doaj   +2 more sources

Intrinsa: testosterone patch for low sexual desire in women [PDF]

Prescriber, 2008
Abstract Intrinsa, a transdermal testosterone patch, is licensed for women with hypoactive sexual desire disorder following bilateral oophorectomy or hysterectomy. Here, Steve Chaplin presents the clinical data relating to its efficacy and adverse effects, and Mr Panay comments on its role in therapy.
Steve Chaplin, Nick Panay
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The testosterone patch for women [PDF]

International Journal of Impotence Research, 2005
Has the FDA discriminated against female sexual dysfunction by not endorsing Procter & Gamble's (P&G) Intrinsa? Has the pendulum swung so far to the right that drugs for sexual medicine receive undue scrutiny? Why is testosterone replacement therapy available for men, but not for women? How should the pharmaceutical industry proceed with future studies?
Sheryl A. Kingsberg
openalex   +3 more sources

Indomethacin Abolishes the Potentiation Effect of Testosterone on the Relaxation Induced by Salbutamol and Theophylline by Directly Blocking the K⁺ Channels in Airway Smooth Muscle [PDF]

Molecules
Indomethacin, ibuprofen, and acetylsalicylic acid (ASA) are non-steroidal anti-inflammatory drugs (NSAIDs) that inhibit prostaglandin (PG) synthesis. Previous studies in airway smooth muscle demonstrated that chronic exposure to testosterone (TES, 40 nM)
Jorge Reyes-García, Abril Carbajal-García, Verónica Díaz-Hernández, María F. Casas-Hernández, Luis M. Montaño   +4 more
doaj   +2 more sources

Transfer of Transdermally Applied Testosterone to Clothing: A Comparison of a Testosterone Patch Versus a Testosterone Gel

The Journal of Sexual Medicine, 2005
ABSTRACT Aim To  assess  the  amount  of  testosterone  transferred  from  the  abdominal  application  sites  of a transdermal testosterone patch and a transdermal testosterone gel to cotton T-shirts worn for 24 hours during each treatment. Methods
Norman A. Mazer, Daniel Fisher, Jerome S. Fischer, Michael Cosgrove, Damon A. Bell, Barbara Eilers   +5 more
openalex   +3 more sources

Testosterone patches in the management of patients with mild/moderate systemic lupus erythematosus [PDF]

Rheumatology, 2007
Androgen deficiency has been associated with the development of systemic lupus erythematosus (SLE). The aim of this study was to test the efficacy of testosterone patches vs placebo in female SLE patients with baseline mild-to-moderate disease activity in a randomized, double-blind, single-centre placebo-controlled trial.Patients received testosterone (
Caroline Gordon, David J. Wallace, Shuntaro Shinada, Kenneth Kalunian, Lindsy Forbess, Glenn D. Braunstein, Michael H. Weisman   +6 more
openalex   +3 more sources