Results 91 to 100 of about 4,135 (231)

Muscle strength changes and physical activity during gender‐affirming hormone therapy: A systematic review

Andrology, EarlyView.
Abstract Background Higher muscle strength is associated with improved overall health and lower mortality. Muscle strength changes during gender‐affirming hormone therapy is possibly linked to gender‐affirming hormone therapy modality, age at initiation, gender‐affirming hormone therapy duration, and physical activity.
Mathilde Kamp Nørlund, Louise Lehmann Christensen, Marianne Skovsager Andersen, Tine Taulbjerg Kristensen, Jan Frystyk, Jonas Mathiesen, Jakob Lindberg Nielsen, Dorte Glintborg   +7 more
wiley   +1 more source

Vitamin D levels and biomarkers of male fecundity: A study from the Danish National Birth Cohort

Andrology, EarlyView.
Abstract Background Vitamin D is metabolised throughout the male reproductive system, suggesting a direct regulatory role of vitamin D in male reproduction. Objectives To investigate the association between plasma vitamin D levels at sperm ejaculation and during spermatogenesis and biomarkers of male fecundity in young men.
Anne Gaml‐Sørensen, Nis Brix, Sandra Søgaard Tøttenborg, Christian Lindh, Karin Sørig Hougaard, Siri Eldevik Håberg, Gunnar Toft, Jens Peter Ellekilde Bonde, Cecilia Høst Ramlau‐Hansen   +8 more
wiley   +1 more source

Cardiovascular safety of testosterone therapy—Insights from the TRAVERSE trial and beyond: A position statement of the European Expert Panel for Testosterone Research

Andrology, EarlyView.
Abstract Introduction Testosterone therapy has become a cornerstone treatment for men with hypogonadism, offering significant benefits such as improved sexual function, mood, muscle mass, and bone density. However, concerns about its cardiovascular safety have historically tempered its use.
Michael Zitzmann, Giulia Rastrelli, Robert D Murray, David Edwards, Yacov Reisman, Preethi Mohan Rao, Alexander Sahi, Thomas Hugh Jones, Alberto Ferlin, Eleni Armeni, Emiliano Corpas, Jann‐Frederik Cremers, Janine David, Stefan Arver, Leen Antonio, Giovanni Corona   +15 more
wiley   +1 more source

Unraveling the intersection of sleep disorders and erectile dysfunction: Outcomes from two EPISONO editions

Andrology, EarlyView.
Abstract Background There is growing interest in the relationship between sleep disorders and erectile dysfunction. We present the results from a 2015 follow‐up study in relation to the 2007 edition of Epidemiologic Sleep Study (EPISONO), a population‐based sleep study conducted in São Paulo, Brazil, and from the 4th edition of EPISONO (2018), with ...
Monica Levy Andersen, Allan Saj Porcacchia, Guilherme Luiz Fernandes, Tathiana A. Alvarenga, Sergio Tufik   +4 more
wiley   +1 more source

Systematic review of PSA reference intervals in the gender diverse population with prostates

BJU International, EarlyView.
Objectives To determine mean/median serum total prostate‐specific antigen (PSA) levels in transgender women and non‐binary people with prostates (TWNBPP) who have received gender‐affirming hormone therapy (GAHT) or an orchidectomy. The secondary objective was to identify other quantitative information that influences PSA levels in this population ...
Rose Hall, Rue Ball, Elizabeth Bancroft, Rosalind Eeles, Alison May Berner   +4 more
wiley   +1 more source

Preferences between three options for androgen deprivation therapy: a focus group study

BJU International, EarlyView.
Objectives Androgen deprivation therapy (ADT) forms the mainstay of treatment for advanced prostate cancer. Traditionally administered as a luteinising hormone‐releasing hormone (LHRH) agonist depot injection, newer options for ADT include transdermal oestradiol patches (tE2) or oral LHRH antagonists.
Hannah L. Rush, Sophie Merrick, John Marshall, John Deighan, Hoda Abdel‐Aty, Abdulla Alhasso, Noel W. Clarke, Roger Kockelbergh, Stephen Mangar, Stuart D. Rosen, Nicholas D. James, Duncan C. Gilbert, Annabelle South, Ruth E. Langley   +13 more
wiley   +1 more source

Individual variation in animal communication: from species averages to unique voices

Biological Reviews, EarlyView.
ABSTRACT The comparative study of communicative behaviour in non‐human animals, especially primates, has yielded crucial insights into the evolution of human language. This research, mostly focused on the species and population level, has improved our understanding of the various socio‐ecological factors that shape communication systems.
Angèle Lombrey, Marlen Fröhlich
wiley   +1 more source

Prognostic and Predictive Value of Machine Learning‐Based Biomarker and Pathomics Signatures in Patients With Prostate Cancer

Cancer Science, EarlyView.
This study develops a metastasis‐associated prognostic risk score (MAPRS), based on multicenter transcriptome data and machine learning algorithms, and validates it using histopathological samples. MAPRS effectively predicts recurrence‐free survival (RFS) and progression‐free survival (PFS) in prostate cancer patients, particularly when combined with ...
Jianpeng Zhang, Jinyou Pan, Jingwei Lin, Yingxin Cai, Yangzhou Liu, Fuyang Lin, Hantian Guan, Gaoxiang Zhou, Daqiang Wei, Zuomin Wang, Yuxiang Ma, Zhigang Zhao   +11 more
wiley   +1 more source

Update on Menopause Hormone Therapy; Current Indications and Unanswered Questions

Clinical Endocrinology, EarlyView.
ABSTRACT Objective To provide clinicians involved in managing menopause with a summary of current evidence surrounding menopause hormone therapy (MHT). Design The authors evaluate and synthesize existing pooled evidence relating to MHT's clinical indications, efficacy, and safety and explore the limitations of existing data. Patients The review focuses
Annice Mukherjee, Susan R. Davis
wiley   +1 more source

Serum Estradiol Concentrations With Estradiol 0.06% Gel in Transgender and Gender‐Diverse Adults

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Transgender and gender‐diverse individuals undergoing estradiol therapy for gender affirmation are typically treated with oral or transdermal estradiol, with transdermal estradiol recommended for those aged > 45 years. There are limited data evaluating estradiol gel in gender‐affirming hormone therapy regimens. We aimed to assess the
Raquel A. Maggacis, Ada S. Cheung, Brendan J. Nolan   +2 more
wiley   +1 more source