Results 131 to 140 of about 16,122 (268)

Human asthenozoospermia: Update on genetic causes, patient management, and clinical strategies

Andrology, EarlyView.
Abstract Background In mammals, sperm fertilization potential relies on efficient progression within the female genital tract to reach and fertilize the oocyte. This fundamental property is supported by the flagellum, an evolutionarily conserved organelle, which contains dynein motor proteins that provide the mechanical force for sperm propulsion and ...
Emma Cavarocchi, Maëva Drouault, Joao C. Ribeiro, Violaine Simon, Marjorie Whitfield, Aminata Touré   +5 more
wiley   +1 more source

Cardiac function and coronary plaque development following masculinizing gender‐affirming hormone therapy: A prospective cohort study

Andrology, EarlyView.
Abstract Introduction Myocardial dysfunction and the presence of calcified and non‐calcified coronary plaques are predictors of cardiovascular disease. Masculinizing gender‐affirming hormone therapy may increase cardiovascular risk, highlighting the need for prospective studies to evaluate cardiovascular outcomes during gender‐affirming hormone therapy.
Laust Frisenberg Buhl, Marianne S. Andersen, Jan Frystyk, Axel Diederichsen, Selma Hasific, Rikke Hjortebjerg, Jordi Sanchez Dahl, Manijeh Noori, Kirstine Nørregaard Hansen, Gitte Maria Jørgensen, Camilla Viola Palm, Tine Taulbjerg Kristensen, Dorte Glintborg, Louise Lehmann Christensen   +13 more
wiley   +1 more source

Luteinizing hormone receptor knockout mouse: What has it taught us?

Andrology, EarlyView.
Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
wiley   +1 more source

Effects of glucagon‐like peptide 1 receptor agonists on testicular dysfunction: A systematic review and meta‐analysis

Andrology, EarlyView.
Abstract Background Hypogonadism and infertility are two conditions that are heavily affected by overweight and obesity in the male patient. Glucagon‐like peptide 1 agonists (GLP‐1RAs) are a recently introduced class of antidiabetic drugs with powerful weight‐loss effect; this may induce an indirect positive effect on the testicular function ...
Gianmaria Salvio, Alessandro Ciarloni, Nicola Ambo, Monia Bordoni, Michele Perrone, Silvia Rossi, Giancarlo Balercia   +6 more
wiley   +1 more source

The effect of topical and intraurethral alprostadil on erectile function: A systematic review and meta‐analysis

Andrology, EarlyView.
Abstract Background Erectile dysfunction (ED) affects up to 50% of men over 40. While phosphodiesterase‐5 inhibitors (PDE5i) are the first line of medical treatment, they are not always effective. Alprostadil, available in injectable, topical, and intraurethral forms, offers an alternative treatment modality.
Iason Papadopoulos, Maksim Tishukov, Ioannis Sokolakis, Ioannis Katafigiotis, Ioannis Leotsakos, Markos Karavitakis, Julian Marcon, Christian G Stief, Nikolaos Pyrgidis   +8 more
wiley   +1 more source

Fetal exposure to a mixture of endocrine‐disrupting chemicals and biomarkers of male fecundity: A population‐based cohort study

Andrology, EarlyView.
Abstract Background Fetal exposure to endocrine‐disrupting chemicals (EDCs) has been associated with reduced male fecundity, but with few studies considering chemical mixtures. Objectives We assessed the association between fetal exposure to a mixture of EDCs and biomarkers of male fecundity in young adulthood.
Sidsel Dan Hull, Karin Sørig Hougaard, Gunnar Toft, Kajsa Kirstine Ugelvig Petersen, Esben Meulengracht Flachs, Christian Lindh, Cecilia Høst Ramlau‐Hansen, Lauren A. Wise, Allen Wilcox, Zeyan Liew, Jens Peter Bonde, Sandra Søgaard Tøttenborg   +11 more
wiley   +1 more source

Semen quality in patients with testicular cancer is associated with age and with greatly elevated levels of beta human chorionic gonadotropin

Andrology, EarlyView.
Abstract Background Poor semen quality is a well‐known feature in patients with testicular germ cell tumours (GCTs) at the time of diagnosis but the underlying biological reasons are incompletely understood. Objectives This study aimed to identify GCT‐specific clinical factors that are involved with poor semen quality in GCT patients.
Klaus‐Peter Dieckmann, Johanna Hochmuth‐Tisch, Andrea Salzbrunn, Cord Matthies, Kathrein von Kopylow, Marta Godlewska, Christian Wülfing, Uwe Pichlmeier, Armin Soave, Christian Guido Ruf   +9 more
wiley   +1 more source

Gonadal function in males with WFS1 spectrum disorder (Wolfram syndrome)—A European cohort perspective

Andrology, EarlyView.
Abstract Background WFS1 spectrum disorder, also known as Wolfram syndrome (WS) is an ultra‐rare (<1:500,000; ORPHA: 3463) monogenic (OMIM #222300) progressive neuroendocrine and neurodegenerative disorder, characterised by early‐onset insulin‐dependent diabetes, optic atrophy, central diabetes insipidus and sensi‐neuronal deafness.
Julia Rohayem, Olivia Cunningham, Denise Williams, Joachim Wistuba, Liam McCarthy, Timothy G. Barrett, Renuka P. Dias   +6 more
wiley   +1 more source

Season of birth and variations in male reproductive health: A population‐based cohort study

Andrology, EarlyView.
Abstract Background Season of birth has been associated with various later reproductive health outcomes in women, but little is known on the potential associations in men. Objectives To investigate the association between season of birth and semen characteristics, testes volume and reproductive hormone levels in young men.
Anne Gaml‐Sørensen, Nis Brix, Sandra Søgaard Tøttenborg, Karin Sørig Hougaard, Siri Eldevik Håberg, Mikko Myrskylä, Gunnar Toft, Jens Peter Ellekilde Bonde, Cecilia Høst Ramlau‐Hansen   +8 more
wiley   +1 more source

Do hormones and surgery improve the health of adults with gender incongruence? A systematic review of patient reported outcomes

ANZ Journal of Surgery, EarlyView.
Gender diverse people in Australia have higher levels of psychological stress, suicidal ideation and suicide attempts and have poorer self‐reported health than cisgender people. A systematic review and meta‐analysis was performed to determine if adults who experience gender incongruence have improved health‐related quality of life and mental health ...
Kelsey Ireland, Madeleine Hughes, Nicola R. Dean   +2 more
wiley   +1 more source