Background Major depressive disorder (MDD) aggregates in families. The neostriatum, key to reward and attachment circuits, has the highest density of serotonin 4 receptors (5‐HT4R). Striatal 5‐HT4R is low in MDD and linked to familial depression risk. Poor parental bonding increases depression risk, yet whether nature and nurture converge on 5‐HT4R is ...
Randi T. Kjær +2 more
wiley +1 more source
Testosterone skin patches improve libido in postmenopausal women not receiving estrogen [PDF]
openaire +1 more source
Understanding Exosomes in Hair Regeneration
Abstract Background Alopecia is a prevalent condition correlated with significant psychosocial challenges, while contemporary treatments exhibit variable efficacy, require extended use, and may cause adverse effects. This review aimed to comprehensively assess exosome‐mediated interventions as a novel cell‐free regenerative approach for hair ...
Paras Ahmad +3 more
wiley +1 more source
Polysaccharide microparticles as an oral vaccine platform: proof-of-concept in male rats using a GnRH-targeting fusion antigen. [PDF]
Wilda M, Rocca MV, Pesca MS, Grigera PR.
europepmc +1 more source
Understanding extracellular vesicles in antiaging
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad +3 more
wiley +1 more source
Five primary melanomas in situ in a patient with recent tanning bed use, melanotan exposure, and anabolic hormone use. [PDF]
Vadner DJ, Smith S.
europepmc +1 more source
Seriality and style: The embodiment, perception, and normalization of collectives
Abstract Within existential phenomenology, both seriality and style have been drawn on to theorize the embodiment and perceptibility of (social) ontological differences. While style refers to how we encounter the world and others not in the abstract, but as immediately and intuitively meaningful, seriality is a form of collective being that pertains to
Tris Hedges
wiley +1 more source
Statistical Discrimination of Urinary Steroid Biomarkers in the Athlete Biological Passport: A Novel Approach to an Abnormal Steroid Profile Score (ASPS). [PDF]
Hopker JG +3 more
europepmc +1 more source
ABSTRACT Background Total adiponectin (TA) is a marker of metabolic health in equids, with values below a critical decision point of < 7.9 μg/mL conferring increased risk of laminitis. Objectives To evaluate an IT assay to measure serum [TA] in equids and to assess its correlation with [high molecular weight adiponectin] (HMWA) measured by ELISA ...
Rose D. Nolen‐Walston +5 more
wiley +1 more source
Natural Sweetener Stevioside-Based Dissolving Microneedles Solubilize Minoxidil for the Treatment of Androgenic Alopecia. [PDF]
Zhang J +7 more
europepmc +1 more source

