The testosterone patch for women [PDF]
International Journal of Impotence Research, 2005 Has the FDA discriminated against female sexual dysfunction by not endorsing Procter & Gamble's (P&G) Intrinsa? Has the pendulum swung so far to the right that drugs for sexual medicine receive undue scrutiny? Why is testosterone replacement therapy available for men, but not for women? How should the pharmaceutical industry proceed with future studies?
S A Kingsberg
semanticscholar +4 more sources
Castration modulates singing patterns and electrophysiological properties of RA projection neurons in adult male zebra finches [PDF]
PeerJ, 2014 Castration can change levels of plasma testosterone. Androgens such as testosterone play an important role in stabilizing birdsong. The robust nucleus of the arcopallium (RA) is an important premotor nucleus critical for singing.
Songhua Wang +5 more
doaj +4 more sources
Clinical Electrophysiology and Mathematical Modeling for Precision Diagnosis of Infertility [PDF]
BiomedicinesHow can cellular electrophysiology measurements and mathematical modeling of ionic channels help to identify pivotal targets in disease-related cell signaling?
Fernanda Carvalho Cavalari +7 more
doaj +2 more sources
Indomethacin Abolishes the Potentiation Effect of Testosterone on the Relaxation Induced by Salbutamol and Theophylline by Directly Blocking the K+ Channels in Airway Smooth Muscle [PDF]
MoleculesIndomethacin, ibuprofen, and acetylsalicylic acid (ASA) are non-steroidal anti-inflammatory drugs (NSAIDs) that inhibit prostaglandin (PG) synthesis. Previous studies in airway smooth muscle demonstrated that chronic exposure to testosterone (TES, 40 nM)
Jorge Reyes-García +4 more
doaj +2 more sources
Intrinsa: testosterone patch for low sexual desire in women [PDF]
Prescriber, 2008 AbstractIntrinsa, a transdermal testosterone patch, is licensed for women with hypoactive sexual desire disorder following bilateral oophorectomy or hysterectomy. Here, Steve Chaplin presents the clinical data relating to its efficacy and adverse effects, and Mr Panay comments on its role in therapy.
S. Chaplin, N. Panay
semanticscholar +3 more sources
Throat patch size and darkness covaries with testosterone in females of a sex-role reversed species [PDF]
Behavioral Ecology, 2011 In male birds, size and blackness of melanin-based ornaments may signal competitive ability and quality. Testosterone is an important physiological mediator of these signals as these ornaments are testosterone dependent. Experimental manipulation of circulating testosterone in females suggests that similar mechanisms are at work in plumage ornaments of
Christina Muck, Wolfgang Goymann
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A Pilot Study of an Investigational Testosterone Transdermal Patch System in Young Women with Spontaneous Premature Ovarian Failure [PDF]
The Journal of Clinical Endocrinology & Metabolism, 2005 Context: Evidence suggests that young women with spontaneous premature ovarian failure (sPOF) have significantly lower androgen levels than age-matched regularly menstruating women. Objective: The objective of the study was to evaluate an investigational testosterone transdermal patch (TTP) designed to deliver the normal ovarian ...
Sophia Kalantaridou +4 more
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Testosterone patch improves ovarian follicular response to gonadotrophins in a patient with Kallmann's syndrome: a case report. [PDF]
Human Reproduction, 2007 Achieving ovulation in women with Kallmann's syndrome requires both exogenous FSH and LH to successfully stimulate follicular maturation and ovarian steroidogenesis. We present a case of a woman with Kallmann's syndrome, who had poor ovarian response to stimulation by exogenous gonadotrophins.
C. Sipe, B. V. Van Voorhis
semanticscholar +4 more sources
Local and Systemic Complications of Local Testosterone Patches and Gels
Journal of Pharmaceutical Research International, 2021 In recent decades, testosterone therapy has gained the attention of many researchers due to the increased demand for this modality worldwide, the increased average age of the different populations, and increased awareness of the potential uses of the modality in clinical settings.
Fahad Ahmed Al-Zahrani +10 more
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Double-blind placebo-controlled study of testosterone patch therapy on bone turnover in men with borderline hypogonadism. [PDF]
International Journal of Andrology, 2006 SummaryClinical studies suggest there may be a threshold concentration of serum testosterone below which replacement will result in skeletal and psychological benefit. We evaluated the response to testosterone in men with borderline hypogonadism. A randomized double‐blind placebo‐controlled trial in 39 men over age 40 years presenting with sexual ...
Z. Merza +8 more
semanticscholar +5 more sources