Results 11 to 20 of about 546,773 (213)

Sexually selected male plumage color is testosterone dependent in a tropical passerine bird, the red-backed fairy-wren (Malurus melanocephalus). [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND: Sexual signals, such as bright plumage coloration in passerine birds, reflect individual quality, and testosterone (T) may play a critical role in maintaining signal honesty.
Willow R Lindsay   +2 more
doaj   +1 more source

Triglyceride-Mimetic Prodrugs of Buprenorphine Enhance Oral Bioavailability via Promotion of Lymphatic Transport

open access: yesFrontiers in Pharmacology, 2022
Buprenorphine (BUP) is a potent opioid analgesic that is widely used for severe pain management and opioid replacement therapy. The oral bioavailability of BUP, however, is significantly limited by first-pass metabolism.
Tim Quach   +8 more
doaj   +1 more source

Mechanism of estradiol-induced block of voltage-gated K+ currents in rat medial preoptic neurons. [PDF]

open access: yesPLoS ONE, 2011
The present study was conducted to characterize possible rapid effects of 17-β-estradiol on voltage-gated K(+) channels in preoptic neurons and, in particular, to identify the mechanisms by which 17-β-estradiol affects the K(+) channels.
Michael Druzin   +3 more
doaj   +1 more source

A Breeding Plumage in the Making: The Unique Process of Plumage Coloration in the Crested Ibis in Terms of Chemical Composition and Sex Hormones

open access: yesAnimals, 2023
The Crested Ibis (Nipponia nippon) has long fascinated ornithologists with its enigmatic plumage color change. After more than a century of curiosity, the mystery was finally unraveled in the 1970s, unveiling the mechanism behind this remarkable ...
Danni Liu   +4 more
doaj   +1 more source

Mental health, Reproductive health and contraception: pharmacological interaction, current evidence and challenges

open access: yesEuropean Psychiatry, 2023
Introduction Mental pathology is relatively prevalent in the women, and there is often a need for treatment with psychotropic drugs, with an impact on women’s reproductive health.
C. Pinto Osório, P. Macedo
doaj   +1 more source

Testosterone patch increases sexual activity and desire in surgically menopausal women with hypoactive sexual desire disorder.

open access: yesJournal of Clinical Endocrinology and Metabolism, 2005
CONTEXT Hypoactive sexual desire disorder (HSDD) is one of the most common sexual problems reported by women, but few studies have been conducted to evaluate treatments for this condition.
J. Simon   +12 more
semanticscholar   +1 more source

Nitric oxide modulates ATP-evoked currents in mouse Leydig cells

open access: yesBrazilian Journal of Medical and Biological Research, 2018
Testosterone synthesis within Leydig cells is a calcium-dependent process. Intracellular calcium levels are regulated by different processes including ATP-activated P2X purinergic receptors, T-type Ca2+ channels modulated by the luteinizing hormone, and ...
J.L. de Deus   +2 more
doaj   +1 more source

Advances in hormone replacement therapy: making the menopause manageable

open access: yesBMC Women's Health, 2008
The importance of the results of some large, randomized controlled trials (RCTs) on Hormone Replacement Therapy (HRT) has modified the risk/benefit perception of HRT. Recent literature review supports a different management.
Palacios Santiago
doaj   +1 more source

Synaptic long-term potentiation and depression in the rat medial vestibular nuclei depend on neural activation of estrogenic and androgenic signals. [PDF]

open access: yesPLoS ONE, 2013
Estrogenic and androgenic steroids can be synthesised in the brain and rapidly modulate synaptic transmission and plasticity through direct interaction with membrane receptors for estrogens (ERs) and androgens (ARs).
Mariangela Scarduzio   +3 more
doaj   +1 more source

Neurosteroids as Selective Inhibitors of Glycine Receptor Activity: Structure-Activity Relationship Study on Endogenous Androstanes and Androstenes

open access: yesFrontiers in Molecular Neuroscience, 2020
The ability of androstane and androstene neurosteroids with modifications at C-17, C-5, and C-3 (compounds 1-9) to influence the functional activity of inhibitory glycine and γ-aminobutyric acid (GABA) receptors was estimated.
Julia V. Bukanova   +2 more
doaj   +1 more source

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