Results 21 to 30 of about 13,419 (307)
Frontiers in Pharmacology, 2022 Buprenorphine (BUP) is a potent opioid analgesic that is widely used for severe pain management and opioid replacement therapy. The oral bioavailability of BUP, however, is significantly limited by first-pass metabolism.
Tim Quach +8 more
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Hedgehog Signalling in Androgen Independent Prostate Cancer [PDF]
, 2008 Objectives: Androgen-deprivation therapy effectively shrinks hormone-naïve prostate cancer, both in the prostate and at sites of distant metastasis.
Bisson, Isabelle +7 more
core +1 more source
Mechanism of estradiol-induced block of voltage-gated K+ currents in rat medial preoptic neurons. [PDF]
PLoS ONE, 2011 The present study was conducted to characterize possible rapid effects of 17-β-estradiol on voltage-gated K(+) channels in preoptic neurons and, in particular, to identify the mechanisms by which 17-β-estradiol affects the K(+) channels.
Michael Druzin +3 more
doaj +1 more source
Animals, 2023 The Crested Ibis (Nipponia nippon) has long fascinated ornithologists with its enigmatic plumage color change. After more than a century of curiosity, the mystery was finally unraveled in the 1970s, unveiling the mechanism behind this remarkable ...
Danni Liu +4 more
doaj +1 more source
2017 Texas Bays and Estuaries Meeting [PDF]
, 2017 Program for the 2017 Texas Bays and Estuaries Meeting held in Port Aransas, Texas, April 12-13, 2017.Coastal Bend Bays & Estuaries Program, Coastal Bend Bays Foundation, The University of Texas Marine Science Institute, Sea Grant Texas at Texas A&M ...
University of Texas Marine Science Institute
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Transdermal delivery of testosterone [PDF]
, 2015 Male hypogonadism has been treated with exogenous testosterone since the 1930s. The early transdermal patches of testosterone became available in the 1980s with gel and solution preparations following subsequent decades.
Hadgraft, J, Lane, ME
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An update on the potential for male contraception : emerging options [PDF]
, 2013 The human population continues to grow and is estimated to rise to 10.1 billion by the end of the century. Therefore, there is still an unmet need for safe and highly effective contraceptive options for both men and women.
Alsaadi, Manal +5 more
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European Psychiatry, 2023 Introduction Mental pathology is relatively prevalent in the women, and there is often a need for treatment with psychotropic drugs, with an impact on women’s reproductive health.
C. Pinto Osório, P. Macedo
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Nitric oxide modulates ATP-evoked currents in mouse Leydig cells
Brazilian Journal of Medical and Biological Research, 2018 Testosterone synthesis within Leydig cells is a calcium-dependent process. Intracellular calcium levels are regulated by different processes including ATP-activated P2X purinergic receptors, T-type Ca2+ channels modulated by the luteinizing hormone, and ...
J.L. de Deus +2 more
doaj +1 more source
Advances in hormone replacement therapy: making the menopause manageable
BMC Women's Health, 2008 The importance of the results of some large, randomized controlled trials (RCTs) on Hormone Replacement Therapy (HRT) has modified the risk/benefit perception of HRT. Recent literature review supports a different management.
Palacios Santiago
doaj +1 more source