Results 61 to 70 of about 563,660 (283)
Molecular biology and evolution, 2023 Carotenoid pigments underlie most of the red, orange, and yellow visual signals used in mate choice in vertebrates. However, many of the underlying processes surrounding the production of carotenoid-based traits remain unclear due to the complex nature ...
Sarah Khalil +11 more
semanticscholar +1 more source
Advanced Science, EarlyView.This research integrated multi‐omics analysis of bone tissue from HLU and control mice revealed that mechanical unloading suppresses intrinsic apoptosis and augments glutamine (Gln) catabolism in osteoclast lineage cells. The findings highlight pivotal roles for SLC1A5‐mediated Gln metabolism and XIAP/Diablo axis‐mediated apoptosis suppression.
Yi Ding +14 more
wiley +1 more source
Drug crystallization – implications for topical and transdermal delivery [PDF]
, 2016 INTRODUCTION: Crystallization of actives in skin following topical application was suggested by studies in the 1950s and 1960s but is poorly understood.
Hadgraft, J, Lane, ME
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A Novel Cultivation System for Germ Cell Proliferation and Sustaining Whole Testicular Niche
Advanced Science, EarlyView.A hydrogel microneedle‐based system enables whole testicular cultivation, supporting spermatogonial proliferation and enhancing spermatogenesis in vitro. This ‘whole testicular spermatogonia pool’ (WTSP) significantly increases spermatid production and fertility potential in mice. This system also promotes spermatogonial expansion in human fetal testes,
Yu Xia +14 more
wiley +1 more source
Health considerations for transgender women and remaining unknowns : a narrative review [PDF]
, 2019 Transgender (trans) women (TW) were assigned male at birth but have a female gender identity or gender expression. The literature on management and health outcomes of TW has grown recently with more publication of research.
Defreyne, Justine +6 more
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Advanced Science, EarlyView.Repeated neonatal sevoflurane exposure impairs adolescent fear memory through Igfbp2 downregulation in paraventricular thalamus‐central amygdala glutamatergic projections. Restoring Igfbp2 or activating this circuit rescues memory deficits, neuronal excitability, and spine density, identifying a precise molecular target for preventing anesthesia ...
Weiming Zhao +16 more
wiley +1 more source
Application of Transdermal Testosterone in Treatment of Male Hypogonadism
Journal of Mazandaran University of Medical Sciences, 2018 Testosterone is one of the most important male steroid hormones that plays a key role in the development of male reproductive tissues. The secretion of this hormone decreases rapidly after age 50. Hypogonadism in men is a clinical syndrome that is caused
Mahgol Tajbakhsh, Majid Saeedi
doaj
Advanced Science, EarlyView.This study demonstrates that patients with PCOS exhibit altered gut microbial profiles, and FMT from PCOS patients induces PCOS‐like symptoms in mice. Specifically, gut dysbiosis reduces 3‐HAA levels in the context of PCOS. Administration of 3‐HAA to mice alleviates PCOS by promoting de novo NAD+ synthesis.
Ke Chen +6 more
wiley +1 more source
Safety and efficacy of testosterone gel in the treatment of male hypogonadism
Clinical Interventions in Aging, 2009 Kishore M Lakshman, Shehzad BasariaSection of Endocrinology, Diabetes, and Nutrition. Boston University School of Medicine, Boston Medical Center, Boston, MA, USAAbstract: Transdermal testosterone gels were first introduced in the US in 2000. Since then,
Kishore M Lakshman, Shehzad Basaria
doaj
Factors affecting breeding status of wading birds in the Everglades. [PDF]
, 2000 This goals of this research and monitoring effort are to document nesting effort and roughly categorize success of nesting by wading birds in the central Everglades of Florida, and to investigate the causes of nonbreeding in a high proportion of the ...
Frederick, Peter C. +3 more
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