Results 141 to 150 of about 24,793 (277)

The prostate after castration and hormone replacement in a rat model: structural and ultrastructural analysis

open access: yesInternational Brazilian Journal of Urology
Purpose: To evaluate if late hormonal replacement is able to recover the prostatic tissue modified by androgenic deprivation. Materials and Methods: 24 rats were assigned into a Sham group; an androgen deficient group, submitted to bilateral orchiectomy
Bruno Felix-Patrício   +7 more
doaj   +1 more source

The effects and safety of testosterone replacement therapy for men with hypogonadism: the TestES evidence synthesis and economic evaluation. [PDF]

open access: yesHealth Technol Assess
Background: Low levels of testosterone cause male hypogonadism, which is associated with sexual dysfunction, tiredness and reduced muscle strength and quality of life.
Cruickshank M   +14 more
europepmc   +2 more sources

Loss‐of‐Function Variants in CCDC189 Cause Human Oligoasthenoteratozoospermia by Disrupting Sperm Flagellar and Acrosomal Architecture

open access: yesAndrology, EarlyView.
ABSTRACT Background Oligoasthenoteratozoospermia (OAT), characterized by reduced sperm count, impaired motility, and abnormal morphology, is a major cause of male infertility with substantial genetic heterogeneity. However, the underlying genetic etiology remains unresolved in a large proportion of affected individuals.
Jianteng Zhou   +8 more
wiley   +1 more source

Neoplastic Risk in Patients With Klinefelter Syndrome

open access: yesAndrology, EarlyView.
ABSTRACT Background Besides gonadal involvement (hypogonadism, male factor infertility, and testicular hypotrophy), patients with Klinefelter syndrome (KS) may suffer from several extra‐gonadic complications, including neoplastic events. Objective The aim of this review is to summarize all major clinical evidence dealing with the association between KS
Andrea Graziani   +4 more
wiley   +1 more source

Oral Testosterone Undecanoate Formulations for Testosterone Replacement Therapy [PDF]

open access: yes
Male hypogonadism, or Testosterone Deficiency (TD), involves decreased testicular function, leading to low androgen levels and impaired sperm production. This condition can negatively impact quality of life and increase cardiovascular risks.
E. Tóth, Béla   +2 more
core   +2 more sources

Feminizing Therapy in People With Klinefelter Syndrome and Gender Incongruence: Considerations for Treatment Without Testosterone Blockers

open access: yesAndrology, EarlyView.
ABSTRACT Background Klinefelter syndrome (KS; 47, XXY) usually involves male sex development and gender identity. Small studies suggest gender incongruence may be more common in KS, but feminizing gender‑affirming hormone therapy in this group has been scarcely reported.
Maaike Kroon   +3 more
wiley   +1 more source

TESTOSTERONE REPLACEMENT THERAPY IN LATE ONSET HYPOGONADISM [PDF]

open access: yes
This paper aims to find out the utility of testosterone replacement therapy (TRT) in managing LOH, focusing on its implications for muscle mass, strength, bone density, sexual function, mood, cognitive abilities, cardiovascular health, and prostate well ...
Duphorn, Antonia Anna Celina
core   +4 more sources

Can Hormonal Therapy Improve the Outcomes of mTESE in Patients With Non‐Obstructive Azoospermia?

open access: yesAndrology, EarlyView.
ABSTRACT Background Non‐obstructive azoospermia (NOA) represents the most severe form of male infertility. Hypogonadism is common in NOA patients, and normal testosterone (T) levels are considered essential for spermatogenesis. Fertility‐preserving hormonal therapy (FpHT) has been proposed to optimize hormonal milieu and improve sperm retrieval rates ...
Mattia Anfosso   +5 more
wiley   +1 more source

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen   +3 more
wiley   +1 more source

Testosterone replacement alters the cell size in visceral fat but not in subcutaneous fat in hypogonadal aged male rats as a late-onset hypogonadism animal model [PDF]

open access: yes, 2015
Amr Abdelhamed,1,2 Shin-ichi Hisasue,1 Masato Shirai,3 Kazuhito Matsushita,1 Yoshiaki Wakumoto,1 Akira Tsujimura,1 Taiji Tsukamoto,4 Shigeo Horie1 1Department of Urology, Juntendo University, Graduate School of Medicine, Tokyo, Japan; 2Department of ...
Tsukamoto T   +7 more
core  

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