Results 121 to 130 of about 24,793 (277)
What anabolic–androgenic steroids reveal about the limits of current harm reduction models
Addiction, EarlyView.Abstract Background Harm reduction has largely been shaped by responses to psychoactive drug use where the most urgent harms are acute. These models focus on overdose, blood‐borne viruses, and rapid‐onset toxicity related harms. When applied wholesale to anabolic–androgenic steroids (AAS), they obscure the distinctive pharmacology, consumer typologies,
Timothy Piatkowski +2 more
wiley +1 more source
The use of deidentified organ donor testes for research
Andrology, EarlyView.Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova +4 more
wiley +1 more source
Testosterone replacement therapy: the emperor's new clothes [PDF]
, 2017 The mean age of the world population has steadily increased in the last decades, as a result of increased life expectancy and reduced birth rate. Global aging has led to a greater worldwide cost for healthcare: hormonal alterations contribute to the ...
SANSONE, ANDREA +3 more
core +1 more source
The role of iron in normal and impaired testicular function
Andrology, EarlyView.Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer +2 more
wiley +1 more source
The role of testosterone replacement therapy following radical prostatectomy. [PDF]
, 2007 Hypogonadism is associated with a decreased serum testosterone level and numerous signs and symptoms, such as decreased libido, erectile dysfunction, decreased muscle mass, increased fat deposition, decreased ability to concentrate, and decreased bone ...
MD Larry I Lipshultz, MD Mohit Khera
core
Andrology, EarlyView.ABSTRACT Background Reconstructing the urethra presents in hypospadias surgery is difficult. Occasionally, the urethral plate (UP) may be quite narrow, necessitating augmentation or replacement to achieve additional tubularization. Objective The objective of this research was to assess the application of modified dorsal inlay graft (mDIG) and ...
Yakun Xu +3 more
wiley +1 more source
Andrology, EarlyView.ABSTRACT Background Klinefelter syndrome is associated with a markedly increased risk of venous thrombosis. While hypogonadism and metabolic dysfunction are known contributors, the role of the contact activation system in Klinefelter syndrome remains unexplored.
Simon Chang +4 more
wiley +1 more source
"Male menopause" : the birth of a new illness? [PDF]
, 2006 The existence of male menopause is uncertain (e.g. Snyder 2004; Rhoden & Morgenthaler 2004) and also the effects of HT have not yet been clarified as being reliably safe.
Vainionpää, Kirsi
core
Andrology, EarlyView.ABSTRACT Background Male hypogonadotropic hypogonadism typically presents with azoospermia and is one of the few causes of infertility amenable to a medical intervention. Gonadotropin therapy offers a chance to restore spermatogenesis and fertility in these individuals.
Manou Huijben +3 more
wiley +1 more source
A Case of Male Osteoporosis: A 37-Year-Old Man with Multiple Vertebral Compression Fractures
Case Reports in Endocrinology, 2017 While the contributing role of testosterone to bone health is rather modest compared to other factors such as estradiol levels, male hypogonadism is associated with low bone mass and fragility fractures.
Suhaib Radi, Andrew C. Karaplis
doaj +1 more source