Results 101 to 110 of about 2,896,861 (274)

Long term testosterone undecanoate replacement therapy: impact of ethnicity.

, 2020
BACKGROUND Testosterone Replacement Therapy (TRT) is indicated for symptomatic male hypogonadism. However, the safety and efficacy profiles across different ethnicities for long term TRT remain unclear.
Andrew Bates, Shepherd, Lisa, Asad Rahim, Kauser, S, Punith Kempegowda, Quinn, Lauren M., Bates, A, Lauren M. Quinn, Kempegowda, Punith; id_orcid, Chandan, J S, Samina Kauser, Joht Singh Chandan, Chandan, Joht Singh; id_orcid, Kauser, Samina, Bates, Andrew, Lisa Shepherd, Rahim, Asad, Shepherd, L, Kempegowda, P, Quinn, L M, Rahim, A   +20 more
core   +1 more source

Evaluation of the effect of testosterone replacement therapy with a transdermal testosterone on glycemic control in men with type 2 diabetes mellitus

Сахарный диабет
BACKGROUND: It is important to evaluate the effect of androgen replacement therapy on glycemic control.AIMS: Assessment of the effect of transdermal testosterone therapy on glycemic control in men with hypogonadism and T2DM.MATERIALS AND METHODS: The ...
R. V. Rozhivanov, M. O. Chernova, V. A. Ioutsi, G. A. Mel’nichenko, M. V. Shestakova, E. R. Rozhivanova, E. N. Andreeva, N. G. Mokrysheva   +7 more
doaj   +1 more source

The use of deidentified organ donor testes for research

Andrology, EarlyView.
Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova, Marnie W. Skinner, Juliana I. Candelaria, Stephen R. Wellard, Philip W. Jordan   +4 more
wiley   +1 more source

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

Microvesicles Correlated with Components of Metabolic Syndrome in Men with Type 2 Diabetes Mellitus and Lowered Testosterone Levels But Were Unaltered by Testosterone Therapy

Journal of Diabetes Research, 2017
Aims. To investigate how circulating microvesicle phenotypes correlate with insulin sensitivity, body composition, plasma lipids, and hepatic fat accumulation.
Jaco Botha, Line Velling Magnussen, Morten Hjuler Nielsen, Tine Bo Nielsen, Kurt Højlund, Marianne Skovsager Andersen, Aase Handberg   +6 more
doaj   +1 more source

Testosterone replacement therapy in adolescents and young men [PDF]

Journal of Men's Health
Guidelines for testosterone replacement therapy (TRT) have been well studied and defined in adults, however, this remains less defined for adolescents and young men.
Alexandra Aponte Varnum, Luke van Leeuwen, David A. Velasquez, Braian Ledesma, Nicholas Allen Deebel, Jason Codrington, Aymara Evans, Alejandro Diaz, David Miller, Ranjith Ramasamy   +9 more
doaj   +1 more source

Contact Activation Is Alleviated by Testosterone Replacement Therapy in Klinefelter Syndrome: Evidence of Hormonal and Metabolic Modulation

Andrology, EarlyView.
ABSTRACT Background Klinefelter syndrome is associated with a markedly increased risk of venous thrombosis. While hypogonadism and metabolic dysfunction are known contributors, the role of the contact activation system in Klinefelter syndrome remains unexplored.
Simon Chang, Claus H. Gravholt, Anne Skakkebæk, Anna‐Marie Bloch Münster, Yaseelan Palarasah   +4 more
wiley   +1 more source

Hypotestosteronaemia in the aging male: should we treat it?

Swiss Medical Weekly, 2015
The term male hypogonadism is defined as the failure to maintain physiological concentrations of testosterone, a physiological quantity of sperm or the combination of both.
Nora Christe, Christoph A. Meier
doaj   +1 more source

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

Andrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

Erythrocytosis Secondary to Testosterone Therapy in a Male with Cryptorchidism: A Case Report

International Journal of Gerontology, 2012
Hypogonadism is association with aging (andropause) can now be recognized earlier and treated with testosterone, thus resulting in the relief of symptoms and better quality of life. However, any patients that are treated with testosterone must be closely
Efthymia Vlachaki, Stella Haralambidou, Chrisoula Pasvanti, Eleni Bekiari, Filippos Klonizakis, Elisavet Ioannidou   +5 more
doaj   +1 more source