Results 151 to 160 of about 216,038 (323)

Testosterone and Depression [PDF]

open access: yes, 2010
Androgens have various effects on human body and mood. Testosterone, a hormone mainly secreted from testes and adrenals, is one of the most potent androgens. Multiple studies have found that testosterone plays a role in regulating sexual activity, libido,
Şükrü Kartalcı
core  

Short‐Term Surgical Outcomes: Modified Dorsal Inlay Graft Versus Tubularized Incised Plate Urethroplasty in Pediatric Hypospadias With Narrow Urethral Plates

open access: yesAndrology, EarlyView.
ABSTRACT Background Reconstructing the urethra presents in hypospadias surgery is difficult. Occasionally, the urethral plate (UP) may be quite narrow, necessitating augmentation or replacement to achieve additional tubularization. Objective The objective of this research was to assess the application of modified dorsal inlay graft (mDIG) and ...
Yakun Xu   +3 more
wiley   +1 more source

Hypogonadism, ADAM, and hormone replacement

open access: yesTherapeutic Advances in Urology, 2010
Male hypogonadism, or testosterone deficiency syndrome (TDS), results from a failure of the testes to produce adequate androgen. Patients have low circulating testosterone in combination with clinical symptoms such as fatigue, erectile dysfunction, and ...
Michael R. Pinsky, Wayne J. G. Hellstrom
doaj   +1 more source

Kyzatrex - Oral testosterone replacement therapy

open access: yesAnnals of Medicine & Surgery, 2022
Asghar, Adam Ali   +3 more
openaire   +2 more sources

Maternal exercise improves vascular function in hypertensive offspring via A‐kinase anchoring protein 150 gene (Akap5) epigenetic modifications

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Regular physical activity is an effective non‐pharmacological approach to hypertension management and maternal exercise improves offspring cardiovascular health, although mechanisms remain unclear. A‐kinase anchoring protein 150 (AKAP150) targets protein kinase Cα to L‐type Ca2+ channels (CaV1.2), enhancing vascular tone in ...
Fang Qiu   +8 more
wiley   +1 more source

Prospective evaluation of low-dose ketoconazole plus hydrocortisone in docetaxel pre-treated castration-resistant prostate cancer patients. [PDF]

open access: yes, 2015
BackgroundKetoconazole is a well-known CYP17-targeted systemic treatment for castration-resistant prostate cancer (CRPC). However, most of the published data has been in the pre-chemotherapy setting; its efficacy in the post-chemotherapy setting has not ...
Beckett, LA   +6 more
core  

Homo sapiens, industrialisation and the environmental mismatch hypothesis

open access: yesBiological Reviews, EarlyView.
ABSTRACT For the vast majority of the evolutionary history of Homo sapiens, a range of natural environments defined the parameters within which selection shaped human biology. Although human‐induced alterations to the terrestrial biosphere have been evident for over 10,000 years, the pace and scale of change has accelerated dramatically since the onset
Daniel P. Longman, Colin N. Shaw
wiley   +1 more source

Update on Menopause Hormone Therapy; Current Indications and Unanswered Questions

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective To provide clinicians involved in managing menopause with a summary of current evidence surrounding menopause hormone therapy (MHT). Design The authors evaluate and synthesize existing pooled evidence relating to MHT's clinical indications, efficacy, and safety and explore the limitations of existing data. Patients The review focuses
Annice Mukherjee, Susan R. Davis
wiley   +1 more source

Effect of thyroid hormone replacement therapy on ovarian volume and androgen hormones in patients with untreated primary hypothyroidism

open access: yesAnnals of Saudi Medicine, 2011
Background and Objectives: Primary hypothyroidism may be associated with ovarian enlargement and/ or cyst formation. We evaluated the effect of thyroid hormone replacement therapy on hormonal changes, ovarian volume and sonographic appearance.
Muderris Iptisam   +3 more
doaj  

Cardiovascular Health in Women—Across the Lifespan

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy