Results 151 to 160 of about 236,531 (317)

The use of deidentified organ donor testes for research

open access: yesAndrology, EarlyView.
Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova   +4 more
wiley   +1 more source

A Case of Male Osteoporosis: A 37-Year-Old Man with Multiple Vertebral Compression Fractures

open access: yesCase Reports in Endocrinology, 2017
While the contributing role of testosterone to bone health is rather modest compared to other factors such as estradiol levels, male hypogonadism is associated with low bone mass and fragility fractures.
Suhaib Radi, Andrew C. Karaplis
doaj   +1 more source

The role of iron in normal and impaired testicular function

open access: yesAndrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer   +2 more
wiley   +1 more source

Hypogonadism, ADAM, and hormone replacement

open access: yesTherapeutic Advances in Urology, 2010
Male hypogonadism, or testosterone deficiency syndrome (TDS), results from a failure of the testes to produce adequate androgen. Patients have low circulating testosterone in combination with clinical symptoms such as fatigue, erectile dysfunction, and ...
Michael R. Pinsky, Wayne J. G. Hellstrom
doaj   +1 more source

Kyzatrex - Oral testosterone replacement therapy

open access: yesAnnals of Medicine & Surgery, 2022
Asghar, Adam Ali   +3 more
openaire   +2 more sources

Low testosterone levels in men at age 31 associates with future risk of prediabetes and type 2 diabetes: A birth cohort study

open access: yesAndrology, EarlyView.
Abstract Objective We aimed to investigate the association of a low serum testosterone concentration with the risk of abnormal glucose metabolism (i.e., prediabetes and type 2 diabetes) in men at a 15‐year follow‐up. Study population and methods In a population birth cohort, men with low testosterone (testosterone < 12.1 nmol/L, n = 136) and normal ...
Tuomisto A   +7 more
wiley   +1 more source

Feminization and severe pancytopenia caused by testicular neoplasia in a cryptorchid dog [PDF]

open access: yes, 2016
In this case report, a paraneoplastic syndrome caused by testicular neoplasia in a ten-year-old cryptorchid dog is described. Feminization and pancytopenia were observed, resulting from the testicular neoplastic production of estrogens.
Hebbelinck, Lien   +3 more
core  

Short‐Term Surgical Outcomes: Modified Dorsal Inlay Graft Versus Tubularized Incised Plate Urethroplasty in Pediatric Hypospadias With Narrow Urethral Plates

open access: yesAndrology, EarlyView.
ABSTRACT Background Reconstructing the urethra presents in hypospadias surgery is difficult. Occasionally, the urethral plate (UP) may be quite narrow, necessitating augmentation or replacement to achieve additional tubularization. Objective The objective of this research was to assess the application of modified dorsal inlay graft (mDIG) and ...
Yakun Xu   +3 more
wiley   +1 more source

Contact Activation Is Alleviated by Testosterone Replacement Therapy in Klinefelter Syndrome: Evidence of Hormonal and Metabolic Modulation

open access: yesAndrology, EarlyView.
ABSTRACT Background Klinefelter syndrome is associated with a markedly increased risk of venous thrombosis. While hypogonadism and metabolic dysfunction are known contributors, the role of the contact activation system in Klinefelter syndrome remains unexplored.
Simon Chang   +4 more
wiley   +1 more source

Prospective evaluation of low-dose ketoconazole plus hydrocortisone in docetaxel pre-treated castration-resistant prostate cancer patients. [PDF]

open access: yes, 2015
BackgroundKetoconazole is a well-known CYP17-targeted systemic treatment for castration-resistant prostate cancer (CRPC). However, most of the published data has been in the pre-chemotherapy setting; its efficacy in the post-chemotherapy setting has not ...
Beckett, LA   +6 more
core  

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