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Testosterone Replacement Therapy and Prostate Health
Current Urology Reports, 2012There is an emerging evolution in the understanding of the relationship between the prostate and testosterone. It has long been generally believed that with testosterone replacement therapy (TRT), increasing serum testosterone levels led to prostatic growth and worsening of voiding dysfunction and associated complications.
A Scott, Polackwich +2 more
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Testosterone replacement therapy: For whom, when and how?
Metabolism: Clinical and Experimental, 2018The finding of low circulating testosterone level in men is relatively frequent. The symptoms of hypogonadism are very frequent in the aging men. However, the diagnosis of hypogonadism is often neglected and the opportunity to replace low testosterone in
C. Tsametis, A. Isidori
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Hormone Therapy: Testosterone Replacement Therapy.
FP essentials, 2023Testosterone levels decrease as men age. When the testes fail to produce an adequate level of endogenous testosterone, men develop hypogonadism. Although the definition of a low testosterone level varies among guidelines, a serum total testosterone level of less than 300 to 350 ng/dL on two separate morning blood samples is considered a low level.
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Advances in Testosterone Replacement Therapy
2008The major goal of androgen substitution is to replace testosterone at levels as close to physiological concentrations as is possible. The mainstay of testosterone susbstitution are parenteral testosterone esters (enanthate and cypionate) to be administered every 2-3 weeks.
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Testosterone Replacement Therapy in Deficient Patients With Chronic Heart Failure
Journal of Cardiovascular Pharmacology and Therapeutics, 2018Background: Testosterone deficiency is associated with heart failure (HF) progression and poor prognosis. Testosterone therapy has been shown to improve exercise capacity in patients with chronic HF, but no trial has evaluated the impact of replacement ...
M. Navarro-Peñalver +10 more
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Blood donation and testosterone replacement therapy
Transfusion, 2017BACKGROUNDPolycythemia is the most common adverse effect of testosterone replacement therapy (TRT) and may predispose patients to adverse vascular events. Current Canadian guidelines recommend regular laboratory monitoring and discontinuing TRT or reducing the dose if the hematocrit exceeds 54% (hemoglobin ≥180 g/L). This threshold has been interpreted
Benjamin, Chin-Yee +4 more
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Testosterone replacement therapy in male hypogonadism
Journal of Endocrinological Investigation, 2003In human males 6-7 mg of testosterone are secreted by the testes in a circadian rhythm with a nocturnal rise in testosterone followed by a decline during the day. Testosterone is necessary to induce and maintain secondary sexual characteristics, lean muscle mass, bone density and for normal sexual behaviour and cognitive function in men.
M, Byrne, E, Nieschlag
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Men behaving madly: testosterone replacement therapy
BMJ, 2010When young, they get overexcited, climb trees, and fight. As adolescents, their earphones blare out thrash metal, and they grunt in response to any question. Testosterone makes them spotty, hairy, and moody, and sport becomes their only social expression.
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[Andrological testosterone replacement therapy].
Der Urologe. Ausg. A, 2009Male hypogonadism is characterised by decreased testicular function, especially testosterone deficiency. Its prevalence increases with age but may be acquired in all stages of life if it is not inborn. The lack of testosterone results in typical clinical symptoms. However, only about 10% of the affected men currently receive adequate treatment.
U, Paasch +2 more
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Testosterone Replacement Therapy and Prostate Cancer
Urologic Clinics of North America, 2007The long-standing concern that testosterone replacement therapy (TRT) may increase the risk of prostate cancer (PCa) has come under new scrutiny. Arguments used to support this concern lack a scientific basis. The original assertion by Huggins that administration of testosterone (T) caused "enhanced growth" of PCa was based on only a single patient ...
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