Results 41 to 50 of about 216,038 (323)

Metabolic Effects of Testosterone Replacement Therapy in Patients with Type 2 Diabetes Mellitus or Metabolic Syndrome: A Meta-Analysis

open access: yesInternational Journal of Endocrinology, 2020
Background Testosterone replacement therapy (TRT) is commonly used for the treatment of hypogonadism in men, which is often associated with type 2 diabetes mellitus (T2DM) and metabolic syndrome (Mets).
Shuying Li   +6 more
semanticscholar   +1 more source

Testosterone Replacement Therapy: Long-Term Safety and Efficacy [PDF]

open access: yesThe World Journal of Men's Health, 2017
Recent position statements and guidelines have raised the distinction between a true and false, age-related hypogonadism (HG) or late-onset hypogonadism (LOH).
Giovanni Corona   +2 more
doaj   +1 more source

Testosterone replacement therapy in blood donors modulates erythrocyte metabolism and susceptibility to hemolysis in cold storage

open access: yesTransfusion, 2020
Red blood cells (RBCs) derived from patients who receive testosterone replacement therapy (TRT) may be considered eligible for component production and transfusion.
Keisha L Alexander   +7 more
semanticscholar   +1 more source

Screening of endocrine organ-specific humoral autoimmunity in 47,XXY Klinefelter's syndrome reveals a significant increase in diabetes-specific immunoreactivity in comparison with healthy control men. [PDF]

open access: yes, 2015
The aim of this study was to evaluate the frequency of humoral endocrine organ-specific autoimmunity in 47,XXY Klinefelter’s syndrome (KS) by investigating the autoantibody profile specific to type 1 diabetes (T1DM), Addison’s disease (AD), Hashimoto ...
ANZUINI, Antonella   +7 more
core   +1 more source

Testosterone Replacement Therapy added to Intensive Lifestyle Intervention in Older Men with Obesity and Hypogonadism.

open access: yesJournal of Clinical Endocrinology and Metabolism, 2020
BACKGROUND Obesity and hypogonadism additively contribute to frailty in older men; however, appropriate treatment remains controversial. OBJECTIVE Determine whether testosterone replacement augments the effect of lifestyle therapy on physical function ...
Y. Barnouin   +10 more
semanticscholar   +1 more source

Testosterone metabolites differentially regulate obesogenesis and fat distribution

open access: yesMolecular Metabolism, 2021
Objective: Low testosterone in men (hypogonadism) is associated with obesity and type II diabetes. Testosterone replacement therapy has been shown to reverse these effects.
Zachary L. Sebo, Matthew S. Rodeheffer
doaj   +1 more source

Androgens and Hypertension in Men and Women: a Unifying View. [PDF]

open access: yes, 2017
This review was designed to revaluate the androgen role on the mechanisms of hypertension and cardiovascular risks in both men and women. Sex steroids are involved in the regulation of blood pressure, but pathophysiological mechanism is not well ...
Carmina, E. 4.   +4 more
core   +1 more source

Late‐onset hypogonadism: Reductio ad absurdum of the cardiovascular risk‐benefit of testosterone replacement therapy

open access: yesAndrology, 2020
Low testosterone (T) level is considered a marker of poor cardiovascular health. Ten years ago, the Testosterone in Older Men with Mobility Limitations (TOM) trial was discontinued due to a higher number of adverse events in men receiving T compared with
F. Sesti   +5 more
semanticscholar   +1 more source

Contemporary treatment options for male hypogonadism

open access: yesJournal of Education, Health and Sport, 2023
Introduction Male hypogonadism is a disease in which testicular function is impaired. Its symptoms are due to testosterone deficiency and most of them show low specificity.
Paweł Sojka   +9 more
doaj   +1 more source

Testosterone Deficiency, Cardiac Health, and Older Men

open access: yesInternational Journal of Endocrinology, 2014
Low levels of testosterone are manifested by erectile dysfunction, reduced sexual desire, and loss of morning erections with increasing numbers of men are being diagnosed and require treatment.
G. Hackett, M. Kirby, A. J. Sinclair
doaj   +1 more source

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