Muscle function following testosterone replacement in men on opioid therapy for chronic non‐cancer pain: A randomized controlled trial [PDF]
, 2022 BACKGROUND: Chronic pain and opioid treatment are associated with increased risk of male hypogonadism and subsequently decreased muscle function. A diagnosis of hypogonadism is based on the presence of low total testosterone and associated symptoms.
Glintborg, Dorte; id_orcid +9 more
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Testosterone metabolites differentially regulate obesogenesis and fat distribution
Molecular Metabolism, 2021 Objective: Low testosterone in men (hypogonadism) is associated with obesity and type II diabetes. Testosterone replacement therapy has been shown to reverse these effects.
Zachary L. Sebo, Matthew S. Rodeheffer
doaj +1 more source
Testosterone Replacement Therapy: Indications, Application Protocols, and Side Effect Profile
Recent Trends in PharmacologyTestosterone Replacement Therapy has evolved from speculative attempts in the 18th and 19th centuries to the isolation and synthesis of the hormone in the 1930s, followed by the development of different and safer methods of administration throughout the ...
Emine Demir, Erol Akpınar
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Contemporary treatment options for male hypogonadism
Journal of Education, Health and Sport, 2023 Introduction Male hypogonadism is a disease in which testicular function is impaired. Its symptoms are due to testosterone deficiency and most of them show low specificity.
Paweł Sojka +9 more
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Testosterone Replacement Therapy in Hypogonadal Men
Endocrinology and Metabolism Clinics of North America, 2022 All approved testosterone replacement methods, when used according to recommendations, can restore normal serum testosterone concentrations, and relieve symptoms in most hypogonadal men. Selection of the method depends on the patient's preference with advice from the physician.
Wang, Christina, Swerdloff, Ronald S
openaire +4 more sources
The Ideal Goal of Testosterone Replacement Therapy: Maintaining Testosterone Levels or Managing Symptoms? [PDF]
, 2019 Typically, the goal of testosterone replacement therapy (TRT) is to restore blood testosterone to normal levels [...
Du Geon Moon, Hyun Jun Park
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Transcriptional Profiling of Luteinizing Hormone Receptor-Deficient Mice Before and after Testosterone Treatment Provides Insight into the Hormonal Control of Postnatal Testicular Development and Leydig Cell Differentiation [PDF]
, 2010 Luteinizing hormone (LH) is a key regulator of male fertility through its effects on testosterone secretion by Leydig cells. Transcriptional control of this is, however, currently poorly understood.
Affara, Nabeel +5 more
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Long term testosterone undecanoate replacement therapy: impact of ethnicity. [PDF]
, 2020 BACKGROUND Testosterone Replacement Therapy (TRT) is indicated for symptomatic male hypogonadism. However, the safety and efficacy profiles across different ethnicities for long term TRT remain unclear.
Andrew Bates +20 more
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Testosterone Deficiency, Cardiac Health, and Older Men
International Journal of Endocrinology, 2014 Low levels of testosterone are manifested by erectile dysfunction, reduced sexual desire, and loss of morning erections with increasing numbers of men are being diagnosed and require treatment.
G. Hackett, M. Kirby, A. J. Sinclair
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Frontiers in Reproductive Health, 2023 Obstructive sleep apnoea syndrome (OSAS) is an under-recognized medical disease. The main risk factors for OSAS are male sex, older age, obesity, and metabolic syndrome, that are also associated with male hypogonadism (MH).
Andrea Graziani +2 more
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