Results 81 to 90 of about 216,038 (323)

Determining the timeline of gonadal and genital differentiation in male and female equine fetuses allows for early detection and intervention in malformations

open access: yesThe Anatomical Record, EarlyView.
Abstract Sexual differentiation in the equine fetus involves coordinated morphogenetic processes that shape both the gonads and the genital ducts. Although the formation of testes and ovaries has been relatively well documented, the temporal dynamics and morphometric patterns of the mesonephric (Wolffian) and paramesonephric (Müllerian) ducts remain ...
Tais Harumi de Castro Sasahara   +4 more
wiley   +1 more source

Are physiological oscillations physiological?

open access: yesThe Journal of Physiology, EarlyView., 2023
Abstract figure legend Mechanisms and functions of physiological oscillations. Abstract Despite widespread and striking examples of physiological oscillations, their functional role is often unclear. Even glycolysis, the paradigm example of oscillatory biochemistry, has seen questions about its oscillatory function.
Lingyun (Ivy) Xiong, Alan Garfinkel
wiley   +1 more source

A perspective on diabetes-related hypogonadism

open access: yesCurrent Medicine Research and Practice, 2021
Testosterone deficiency leads to hypogonadism, which has shown a direct correlation with Type 2 diabetes mellitus. Hypogonadotropic hypogonadism is the major classification of hypogonadism, based on origin, which is related with diabetes.
Shikhar Tripathi   +3 more
doaj   +1 more source

Testosterone Replacement Therapy and the Risk of Prostate Cancer in Men with Late-Onset Hypogonadism.

open access: yesAmerican Journal of Epidemiology, 2019
The association between the use of testosterone replacement therapy (TRT) and prostate cancer remains uncertain. Thus, we investigated whether TRT is associated with an increased risk of prostate cancer in men with late-onset hypogonadism.
Chris Santella   +4 more
semanticscholar   +1 more source

Burden of Liver Disease Among Individuals With Turner Syndrome and Klinefelter Syndrome: A Comprehensive Perspective

open access: yesChronic Diseases and Translational Medicine, EarlyView.
ABSTRACT The liver is increasingly recognized as a major regulator of systemic cardio‐renal‐metabolic health. Evidence is mounting that sex‐chromosome dosage per se itself, independent of gonadal sex hormones, modulates hepatic physiology and liver disease risk.
Mohamad Jamalinia   +2 more
wiley   +1 more source

Pancreas Cancer-Associated Weight Loss. [PDF]

open access: yes, 2019
Unintentional weight loss in patients with pancreatic cancer is highly prevalent and contributes to low therapeutic tolerance, reduced quality of life, and overall mortality.
Denlinger, Crystal S   +7 more
core  

The postfinasteride syndrome; an overview [PDF]

open access: yes, 2016
As a 5-α reductase inhibitor, Finasteride has proven effective in ameliorating two conditions documented to be androgen dependent, namely male androgenic alopecia and benign prostatic hyperplasia. Therapeutic results are maintained as long as the drug is
Banu, Petrisor   +9 more
core   +4 more sources

Off label therapies for testosterone replacement [PDF]

open access: yesTranslational Andrology and Urology, 2016
The incidence of hypogonadism has been steadily increasing over the last few years. Exogenous testosterone has been the standard treatment for hypogonadal men, but is associated with suppression of spermatogenesis as well as other possible adverse effects.
DiGiorgio, Lorenzo   +1 more
openaire   +2 more sources

Investigations Into the Human Metabolism of Trestolone (7α‐Methyl‐19‐Nortestosterone)

open access: yesDrug Testing and Analysis, EarlyView.
As the known metabolites of 7α‐methyl‐19‐nortestosterone (MENT), M1 and M2, suffer from chromatographic issues under routine doping control conditions, the human metabolism of MENT was reinvestigated. From the numerous new metabolites detected, especially, M5 and M10 were identified as the most promising candidates to be implemented into routine ...
Thomas Piper   +2 more
wiley   +1 more source

Gonadal hormones, but not sex, affect the acquisition and maintenance of a Go/No-Go odor discrimination task in mice [PDF]

open access: yes, 2018
In mice, olfaction is crucial for identifying social odors (pheromones) that signal the presence of suitable mates. We used a custom-built olfactometer and a thirst-motivated olfactory discrimination Go/No-Go (GNG) task to ask whether discrimination of ...
Bass, M.   +5 more
core   +1 more source

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