Results 1 to 10 of about 209,840 (195)

Listeria delivers tetanus toxoid protein to pancreatic tumors and induces cancer cell death in mice

Science Translational Medicine, 2022
Pancreatic ductal adenocarcinoma (PDAC) is a highly metastatic disease. Tumors are poorly immunogenic and immunosuppressive, preventing T cell activation in the tumor microenvironment.
B. Selvanesan, D. Chandra, Wilber Quispe-Tintaya, Arthee Jahangir, Ankur Patel, K. Meena, Rodrigo Alberto Alves Da Silva, Madeline Friedman, L. Gabor, Olivia Khouri, S. Libutti, Ziqiang Yuan, Jenny Li, Sarah Siddiqui, A. Beck, L. Tesfa, W. Koba, J. Chuy, J. Mcauliffe, Rojin Jafari, D. Entenberg, Yarong Wang, J. Condeelis, Vera M. Desmarais, V. Balachandran, Xusheng Zhang, Ken Lin, C. Gravekamp   +27 more
semanticscholar   +1 more source

Toxicology and pharmacology of botulinum and tetanus neurotoxins: an update

Archives of Toxicology, 2022
Tetanus and botulinum neurotoxins cause the neuroparalytic syndromes of tetanus and botulism, respectively, by delivering inside different types of neurons, metalloproteases specifically cleaving the SNARE proteins that are essential for the release of ...
M. Pirazzini, C. Montecucco, O. Rossetto
semanticscholar   +1 more source

Prevalence and determinants of antenatal tetanus vaccination in Sudan: a cross-sectional analysis of the Multiple Indicator Cluster Survey

Tropical Medicine and Health, 2022
Background Tetanus vaccination is an indispensable component of the antenatal care (ANC) and is considered one of the most effective and protective measures against tetanus deaths. However, data on antenatal tetanus vaccination in Sudan are scarce.
S. Mohamed, E. Ahmed
semanticscholar   +1 more source

Tetanus and tetanus neurotoxin: From peripheral uptake to central nervous tissue targets

Journal of Neurochemistry, 2021
Tetanus is a deadly but preventable disease caused by a protein neurotoxin produced by Clostridium tetani. Spores of C. tetani may contaminate a necrotic wound and germinate into a vegetative bacterium that releases a toxin, termed tetanus neurotoxin ...
A. Megighian, M. Pirazzini, F. Fabris, O. Rossetto, C. Montecucco   +4 more
semanticscholar   +1 more source

Waning immunity after receipt of Pertussis, Diphtheria, Tetanus and Polio-related vaccines: a systematic review and meta-analysis.

Journal of Infectious Diseases, 2021
DTP-containing (pertussis, diphtheria and tetanus) combined with polio vaccines are recommended by WHO as part of routine immunization programs. The decline of immunity after vaccination has been considered as a possible reason for the re-emergence of ...
Huizhi Gao, E. Lau, B. Cowling
semanticscholar   +1 more source

Use of Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis Vaccines: Updated Recommendations of the Advisory Committee on Immunization Practices — United States, 2019

MMWR. Morbidity and mortality weekly report, 2020
Since 2005, a single dose of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine has been recommended by the Advisory Committee on Immunization Practices (ACIP) for adolescents and adults (1,2).
F. Havers, P. Moro, P. Hunter, S. Hariri, H. Bernstein   +4 more
semanticscholar   +1 more source

An Unusual Case of Chronic Relapsing Tetanus Associated with Mandibular Osteomyelitis [PDF]

, 2009
A 55-year-old man underwent radiation therapy due to malignant lymphoma of the neck. Eight years after the therapy he developed tetanus. It appears that the radiation therapy resulted in mandibular necrosis, and that this lesion may have been the ...
Fujimuro, Masahiro, Jackson, Mandy, Kawarabayashi, Takeshi, Kimura, Tamaki, Matsubara, Etsuro, Nakahata, Naoko, Seino, Yusuke, Shirahama, Ikumi, Shoji, Mikio, Suzuki, Chieko, Takamura, Ayumi, Tomiyama, Masahiko, Wakasaya, Yasuhito, Watanabe, Mitsunori, Yamamoto-Watanabe, Yukiko   +14 more
core   +1 more source

Mandatory vaccinations in European countries, undocumented information, false news and the impact on vaccination uptake: the position of the Italian pediatric society. [PDF]

, 2018
BACKGROUND: High rates of vaccination coverage are important in preventing infectious diseases. Enforcing mandatory vaccinations is one of the strategies that some Countries adopted to protect the community when vaccination coverage is not satisfactory ...
Bozzola E, Bozzola M, Corsello G, Russo R, Spina G, Villani A   +5 more
core   +2 more sources

Tetanus Toxoid Vaccination Uptake and Associated Factors among Mothers Who Gave Birth in the Last 12 Months in Errer District, Somali Regional State, Eastern Ethiopia

BioMed Research International, 2020
Background Maternal tetanus is defined as tetanus acquired during pregnancy or within 6 weeks after the end of conception. As tetanus is a vaccine-preventable disease, immunization of pregnant mothers with a TT (tetanus toxoid) dose is one of the most ...
T. Gebremedhin, F. Welay, Meresa Berwo Mengesha, Natnael Etsay Assefa, Weldu Mammo Werid   +4 more
semanticscholar   +1 more source

Loss of AP-3 function affects spontaneous and evoked release at hippocampal mossy fiber synapses [PDF]

, 2006
Synaptic vesicle (SV) exocytosis mediating neurotransmitter release occurs spontaneously at low intraterminal calcium concentrations and is stimulated by a rise in intracellular calcium.
A. Scheuber, Blagoveshchenskaya, Dell'Angelica, Fa  ndez, G. Raposo, Goda, Guti  rrez, Hayashi, J.-C. Poncer, Kamiya, Kantheti, L. Danglot, Li, Lopantsev, Musleh, Muzerelle, R. Rudge, Rizzoli, Rosenmund, Sakaba, Schoch, Sj  str  m, Stobrawa, Stoppini, Sudhof, Sugita, Sugita, T. Binz, T. Galli, Takei, Vogt, Woodhall, Xu   +32 more
core   +6 more sources