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Journal of Veterinary Diagnostic Investigation, 2020 Tetanus is a neurologic disease of humans and animals characterized by spastic paralysis. Tetanus is caused by tetanus toxin (TeNT) produced by Clostridium tetani, an environmental soilborne, gram-positive, sporulating bacterium.
M. Popoff
semanticscholar +7 more sources
Loss of AP-3 function affects spontaneous and evoked release at hippocampal mossy fiber synapses [PDF]
Proc Natl Acad Sci U S A (20/10/2006) sous presse, 2006 Synaptic vesicle (SV) exocytosis mediating neurotransmitter release occurs spontaneously at low intraterminal calcium concentrations and is stimulated by a rise in intracellular calcium. Exocytosis is compensated for by the reformation of vesicles at plasma membrane and endosomes.
A. Scheuber +32 more
arxiv +7 more sources
Mortality from tetanus between 1990 and 2015: findings from the global burden of disease study 2015
BMC Public Health, 2017 Background Although preventable, tetanus still claims tens of thousands of deaths each year. The patterns and distribution of mortality from tetanus have not been well characterized.
Hmwe H. Kyu +7 more
doaj +2 more sources
Tetanus development during hospitalization in an older adult [PDF]
IDCasesTetanus is a fatal infectious disease caused by neurotoxins produced by Clostridium tetani. Currently, tetanus has no confirmatory tests; it is often diagnosed based on clinical signs and symptoms.
Naoki Okawa, Naoto Hosokawa
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Autonomic nervous system dysfunction predicts poor prognosis in patients with mild to moderate tetanus [PDF]
BMC Neurology, 2005 Background Autonomic nervous system (ANS) dysfunction is present in up to one third of patients with tetanus. The prognostic value of ANS dysfunction is known in severe tetanus but its value is not well established in mild to moderate tetanus.
Shamsi Rohmah +5 more
doaj +6 more sources
Cephalic Tetanus: A Case Report [PDF]
Case Reports in Infectious Diseases, 2011 A case report of cephalic tetanus in a 2-year-old girl who was not immunized against tetanus following suppurative otitis media (SOM) is presented.
M. A. Alhaji +3 more
doaj +4 more sources
Assessing the impact of the 2018 tetanus guidelines on knowledge and practices of emergency physicians in trauma patients: a national survey study [PDF]
PeerJ, 2023 Background Tetanus remains a significant public health issue in China, with the approach of anti-tetanus prophylaxis in the emergency department resulting in both overuse, particularly of human tetanus immune globulin (TIG), and underuse with the tetanus
Junling Gao +10 more
doaj +2 more sources
Clinical Profile, Management and Outcome in Paediatric Patients with Tetanus: A Case Series [PDF]
Journal of Clinical and Diagnostic Research, 2023 Tetanus is an acute infectious disease, caused by spores of the bacterium Clostridium tetani. The spores are found everywhere in the environment, particularly in soil, ash, intestinal tracts/faeces of animals and humans, on the surfaces of skin and rusty
Arpita Manish Patel +4 more
doaj +1 more source
Tetanus and tetanus neurotoxin: From peripheral uptake to central nervous tissue targets
Journal of Neurochemistry, 2021 Tetanus is a deadly but preventable disease caused by a protein neurotoxin produced by Clostridium tetani. Spores of C. tetani may contaminate a necrotic wound and germinate into a vegetative bacterium that releases a toxin, termed tetanus neurotoxin ...
A. Megighian +4 more
semanticscholar +1 more source
Acute Medicine & Surgery, 2023 Vaccines for tetanus prevention have rapidly progressed, and the number of outbreaks, especially the incidence of tetanus in developed countries, has decreased dramatically. However, the mortality rate associated with severe tetanus remains high. Tetanus
Junko Yamaguchi, Kosaku Kinoshita
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