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Tetanus is a neurologic disease of humans and animals characterized by spastic paralysis. Tetanus is caused by tetanus toxin (TeNT) produced by Clostridium tetani, an environmental soilborne, gram-positive, sporulating bacterium. The disease most often results from wound contamination by soil containing C. tetani spores.
openaire +4 more sources
Penggunaan Anti Tetanus Serum dan Human Tetanus Immunoglobulin pada Tetanus Anak
Latar belakang. Salah satu pilar terapi kasus tetanus adalah netralisasi toksin tetanus dalam sirkulasi. Terdapat dua pilihan terapi netralisasi toksin, yaitu anti tetanus serum (ATS) yang berasal dari serum kuda dan human tetanus immunoglobulin (HTIG ...
Martinus M. Leman, Alan R. Tumbelaka
doaj +1 more source
Interventions to reduce neonatal mortality from neonatal tetanus in low and middle income countries - a systematic review [PDF]
Background In 1988, WHO estimated around 787,000 newborns deaths due to neonatal tetanus. Despite few success stories majority of the Low and Middle Income Countries (LMICs) are still struggling to reduce neonatal mortality due to neonatal tetanus.
Khan, Adeel Ahmed+2 more
core +2 more sources
A solid approach to biopharmaceutical stabilisation [PDF]
Ensilication is a technology we developed that can physically stabilise proteins in silica without use of a pre-formed particle matrix. Stabilisation is done by tailor fitting individual proteins with a silica coat using a modified sol-gel process. Biopharmaceuticals, for example, liquid-formulated vaccines with adjuvants, have poor thermal stability ...
arxiv +1 more source
Epileptic high-frequency network activity in a model of non-lesional temporal lobe epilepsy [PDF]
High-frequency cortical activity, particularly in the 250–600 Hz (fast ripple) band, has been implicated in playing a crucial role in epileptogenesis and seizure generation. Fast ripples are highly specific for the seizure initiation zone.
Cmejla, Roman+5 more
core +3 more sources
Monolithic Biohybrid Flexure Mechanism Actuated by Bioengineered Skeletal Muscle Tissue
A scalable, monolithic biohybrid flexure mechanism is presented, integrating engineered skeletal muscle tissue with a soft, biocompatible, hollow silicone cylinder featuring dual pillars. Muscle contraction induces bending motion upon electrical stimulation, with performance governed by the structure's flexural rigidity.
Andrea Bartolucci+13 more
wiley +1 more source
Balancing Antigen Loading on Gold Nanoparticles: Implications for Future Cancer Vaccine Strategies
The synthesis of multicomponent cancer vaccines on AuNP carriers could be rationalized by the simultaneous functionalization of the antigen and immunomodulator components on the same particles. Immunization with a “diluted” amount of MUC1‐functionalized AuNPs is still capable of eliciting a strong immune response.
Mattia Ghirardello+8 more
wiley +1 more source
Tetanus Following Canine Bite in Japan: A Case Report and Literature Review
Jun Hirai,1,2 Nobuaki Mori,1,2 Yuichi Shibata,2 Nobuhiro Asai,1,2 Mao Hagihara,3 Hiroshige Mikamo1,2 1Department of Clinical Infectious Diseases, Aichi Medical University Hospital, Nagakute, Aichi, Japan; 2Department of Infection, Prevention, and Control,
Hirai J+5 more
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