Results 1 to 10 of about 6,099 (156)

Dermal Concentration Versus Systemic Bioavailability of Topical Lidocaine and Tetracaine: An Exploratory Pharmacokinetic Pilot Study in Göttingen Minipigs [PDF]

open access: yesPharmaceutics
Background: Lidocaine, classified as an amide-type agent, and tetracaine, designated as an ester-type agent, are frequently co-formulated for dermatologic procedures.
Paweł Biernat   +5 more
doaj   +2 more sources

Tetracaine Eye Drops as a Preemptive Topical Skin Anesthesia for Botulinum Toxin Type A Injections in Blepharospasm Patients: A Randomized Controlled Trial [PDF]

open access: yesClinical Ophthalmology
Navinda Pinitpanich,1,* Parima Hirunwiwatkul,1,2,* Chuthamas Ongprakobkul,1,2 Wasee Tulvatana1,2 1Ophthalmology Department, King Chulalongkorn Memorial Hospital, Bangkok, Thailand; 2Department of Ophthalmology, Faculty of Medicine ...
Pinitpanich N   +3 more
doaj   +2 more sources

Research on the use of tetracaine hydrochloride jelly surface anesthesia in combination with intravenous anesthesia for pain-free cystoscopy [PDF]

open access: yesFrontiers in Medicine
ObjectiveThis study aimed to evaluate the efficacy and safety of tetracaine hydrochloride jelly surface anesthesia in combination with intravenous anesthesia for painless cystoscopy.MethodsThis study was conducted at the Department of Urology, Beijing ...
Wenjie Bai   +4 more
doaj   +2 more sources

Metabolomics Changes of Serum and Tissues in Mice Died of Acute Tetracaine Poisoning [PDF]

open access: yesFayixue Zazhi, 2021
Objective To study the changes of metabolites in serum and tissues (kidney, liver and heart) of mice died of acute tetracaine poisoning by metabolomics, to search for potential biomarkers and related metabolic pathways, and to provide new ideas for the ...
LIU Wen-qiao, BAI Rui, MA Chun-ling, et al.
doaj   +1 more source

Dorsal penile nerve block alleviates pain in men undergoing rigid cystoscopy: A single‐center, randomized, double‐blind, and placebo‐controlled trial

open access: yesBJUI Compass, 2021
Objective To assess the effectiveness and safety of dorsal penile nerve block (DPNB) compared with tetracaine gel in analgesia for men undergoing rigid cystoscopy.
Yan Qiu   +3 more
doaj   +1 more source

FORMULATION AND EVALUATION OF TETRACAINE HYDROCHLORIDE POLYMERIC FILMS FOR TOPICAL APPLICATION [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University, 2003
Eudragit polymeric films were investigated as a potential drug delivery system forcontrolling the release of tetracaine HCl. The effect of modification in polymeric ratio of bothEudragit RS100 and RL100, drug loading and nature of plasticizer on the in ...
M. Amin   +3 more
doaj   +1 more source

Efficacy and safety of a lidocaine/tetracaine medicated patch or peel for dermatologic procedures: a meta-analysis [PDF]

open access: yesKorean Journal of Anesthesiology, 2012
BackgroundTo justify the use of the lidocaine/tetracaine medicated patch or peel as a preventive treatment for reducing pain and discomfort in adults and children. We reviewed randomized controlled trials (RCTs) to evaluate the efficacy and safety of the
Won Oak Kim   +2 more
doaj   +1 more source

The influence of non polar and polar molecules in mouse motile cells membranes and pure lipid bilayers. [PDF]

open access: yesPLoS ONE, 2013
We report an experimental study of mouse sperm motility that shows chief aspects characteristic of neurons: the anesthetic (produced by tetracaine) and excitatory (produced by either caffeine or calcium) effects and their antagonic action.
Francisco J Sierra-Valdez   +5 more
doaj   +1 more source

Mechanisms Underlying the Strong Inhibition of Muscle-Type Nicotinic Receptors by Tetracaine

open access: yesFrontiers in Molecular Neuroscience, 2018
Nicotinic acetylcholine (ACh) receptors (nAChRs) are included among the targets of a variety of local anesthetics, although the molecular mechanisms of blockade are still poorly understood.
Raúl Cobo   +6 more
doaj   +1 more source

Effect of four local anesthetics (tetracaine, bupivacaine, lidocaine and proparacaine) on intraocular pressure in rabbits- Comparison of an applanation and a rebound tonometer [PDF]

open access: yesThe Iranian Journal of Veterinary Science and Technology, 2020
The type of device used, the type of local anesthetic agents, and the animal species may affect the intraocular pressure(IOP). Therefore, in order to determine these issues, the effects of four local anesthetics were investigated in 10 adult rabbits by ...
Arman Emrarian, Ali Asghar Sarchahi
doaj   +1 more source

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