Synergistic Interaction and Binding Efficiency of Tetracaine Hydrochloride (Anesthetic Drug) with Anionic Surfactants in the Presence of NaCl Solution Using Surface Tension and UV–Visible Spectroscopic Methods [PDF]
Gels, 2022 Surfactants are ubiquitous materials that are used in diverse formulations of various products. For instance, they improve the formulation of gel by improving its wetting and rheological properties. Here, we describe the effects of anionic surfactants on
Naved Azum +4 more
doaj +2 more sources
Mixed Micellization, Thermodynamic and Adsorption Behavior of Tetracaine Hydrochloride in the Presence of Cationic Gemini/Conventional Surfactants [PDF]
Gels, 2022 In this approach, tensiometry and UV-visible techniques are used to determine the effect of cationic gemini and conventional surfactants on tetracaine hydrochloride (TCH), an anesthetic drug.
Naved Azum +5 more
doaj +2 more sources
Research on the use of tetracaine hydrochloride jelly surface anesthesia in combination with intravenous anesthesia for pain-free cystoscopy [PDF]
Frontiers in MedicineObjectiveThis study aimed to evaluate the efficacy and safety of tetracaine hydrochloride jelly surface anesthesia in combination with intravenous anesthesia for painless cystoscopy.MethodsThis study was conducted at the Department of Urology, Beijing ...
Wenjie Bai +4 more
doaj +2 more sources
Tetracaine hydrochloride induces macrophage pyroptosis through caspase‑1/11‑GSDMD signaling pathways. [PDF]
Exp Ther Med, 2023 Tetracaine hydrochloride (TTC) is a long-lasting local anesthetic commonly used for topical anesthesia. Inappropriate dosage or allergic reactions to TTC can lead to local anesthetic toxicity. TTC exerts cytotoxic effects on certain cell types by inducing apoptosis and necrosis; however, the effects of TTC on macrophages are currently unclear.
Zhang R +8 more
europepmc +3 more sources
Topical anesthetics for needle-related pain in adults and children (TOPIC): a mini-review [PDF]
Frontiers in Pain Research, 2023 PurposeHealthcare professionals (HCP) perform various needle procedures that can be distressing and painful for children and adults. Even though many strategies have been proven effective in reducing distress and pain, topical anesthetic use before ...
Sylvie Le May +20 more
doaj +2 more sources
Solvent-Driven Enrichment and Multiplex Analysis of Local Anesthetics by Thin-Layer Chromatography Coupled with Surface-Enhanced Raman Spectroscopy [PDF]
MoleculesLocal anesthetics have been widely used in clinical analgesia due to their ability to provide effective regional pain management. Accurate measurement of local anesthetics in body fluids is crucial for ensuring patient medication safety and optimizing ...
Huimin Sui +9 more
doaj +2 more sources
Assessment of Dry Eye Disease Symptoms in Health Science University Students: A Combined Approach Using CVS-Q and Schirmer Tear Test to Evaluate the Influence of Digital Devices [PDF]
Clinical OptometryRagad Allwihan,1,2 Amani Y Alhalwani,1,2 Abdullah Aleissa,1,2 Ali S Alsudais,3 Mohammed F Gholam2,3 1Basic Sciences Department, College of Science and Health Professions, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia ...
Allwihan R +4 more
doaj +2 more sources
Journal of Ophthalmology, 2021 Purpose. We investigated the effect of age and sex on corneal touch threshold (CTT) and duration of action following administration of 0.5% topical ophthalmic proparacaine and tetracaine hydrochlorides. Methods. A prospective, randomized, subject-masked,
Samuel Kyei +4 more
doaj +1 more source
Manufacture of tetracaine hydrochloride lozenges preparation by direct compression and wet granulation methods [PDF]
Vojnosanitetski Pregled, 2002 The results of quality testing of lozenges made by direct compression and by wet granulation procedure (Ph. Jug. IV) are presented. The aim was to determine hardness, friability and disintegration of the lozenges.
Gazikalović Emilija +3 more
doaj +1 more source
Cytotoxic effect and possible mechanisms of Tetracaine on human corneal epithelial cells in vitro [PDF]
International Journal of Ophthalmology, 2016 AIM: To demonstrate the cytotoxic effect and possible mechanisms of Tetracaine on human corneal epithelial (HCEP) cells in vitro. METHODS: In vitro cultured HCEP cell were treated with Tetracaine hydrochloride at different doses for different times, and
Xin Pang, Ting-Jun Fan
doaj +1 more source