Results 41 to 50 of about 3,260 (193)

Murine Biocompatibility Evaluation of an Albumin‐Derived Complex and Nanoparticle Delivery System for Ocular Applications

open access: yesJournal of Biomedical Materials Research Part A, Volume 114, Issue 3, March 2026.
ABSTRACT Age‐related macular degeneration (AMD) is a leading cause of irreversible vision loss in the aging population, with no curative treatment currently available. Current therapies primarily target late‐stage symptoms and are limited by their frequent and invasive intravitreal (IVT) injections.
Amna Abdalbaqi   +4 more
wiley   +1 more source

Dietary inulin affects the intestinal microbiota in sows and their suckling piglets [PDF]

open access: yes, 2015
Background: Several studies have focused on the effects of dietary inulin on the intestinal microbiota of weaned piglets. In the present study, inulin was added to a diet for gestating and lactating sows, expecting not only effects on the faecal ...
Paßlack, Nadine   +2 more
core   +2 more sources

Anogenital Contact Dermatitis in Spain: A REIDAC Study of Patients Undergoing Patch Testing in 2019–2024

open access: yesContact Dermatitis, Volume 94, Issue 3, Page 272-285, March 2026.
Allergic contact dermatitis is very common in patients with anogenital lesions referred for patch testing in Spain. Key allergens include fragrances, preservatives and topical treatments like anaesthetics and steroids. Emerging sensitisers including benzisothiazolinone and sodium metabisulphite are also relevant.
Mercè Grau‐Pérez   +29 more
wiley   +1 more source

Ultrasonographic Ocular Biometry of the Greater Caribbean Manatee (Trichechus manatus manatus)

open access: yesVeterinary Ophthalmology, Volume 29, Issue 2, March 2026.
ABSTRACT This study aimed to characterize the ocular biometry of the Trichechus manatus manatus applying B‐mode ultrasonography across different age groups. Twenty‐two animals were assessed employing a portable ultrasound device equipped with a linear transducer. Five ocular parameters were assessed: corneal thickness (CT), anterior chamber depth (ACD),
Radan Elvis Matias de Oliveira   +10 more
wiley   +1 more source

Early sensorimotor restriction in rats induces age‐dependent mitochondrial alterations in skeletal muscles and brain structures

open access: yesThe Journal of Physiology, Volume 604, Issue 6, Page 2512-2524, 15 March 2026.
Abstract figure legend This study aimed to determine whether early sensorimotor restriction (SMR) alters mitochondrial enzyme activities in rat muscles and brain structures. SMR was induced via immobilizing the hind limbs of pups for 16 h per day during the dark phase from birth to postnatal day (PND) 28.
Mélanie Van Gaever   +4 more
wiley   +1 more source

MSC‐Derived Exosomal lnc‐AGT‐3: A Novel Anti‐Angiogenic Target in Age‐Related Macular Degeneration Through p53 Signaling Pathway

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
MSC‐derived exosomes deliver lnc‐AGT‐3 to vascular endothelial cells, where it binds hnRNP K in the nucleus. This interaction inhibits p53 ubiquitination, enhancing p53 stabilization and transcriptional activation of anti‐angiogenic targets TSP1. Consequently, p53‐mediated signaling is potentiated, effectively suppressing choroidal neovascularization ...
Lingjie Kong   +9 more
wiley   +1 more source

Posterior Sub-Tenon Triamcinolone Injection for Chronic Macular Oedema Associated With Non-Ischemic Branch or Central Retinal Vein Occlusion [PDF]

open access: yes, 2016
Aims: To evaluate the effectiveness and safety of Posterior Sub-Tenon (PST) Triamcinolone Acetonide (TA) injection for persistent macular oedema associated with non-ischemic Central Retinal Vein Occlusion (CRVO) or Branch Retinal Vein Occlusion (BRVO) in
Aude Ambresin   +9 more
core   +1 more source

Duration of the local anesthetic effect of tetracaine hydrochloride solutions and tetracaine in microspheres.

open access: yesJournal of Pharmacobio-Dynamics, 1982
The local anesthetic effect of tetracaine in polylactic acid microspheres was compared with that of tetracaine hydrochloride solutions. As a first step, the local anesthetic effect of 0.1 ml tetracaine hydrochloride solutions was examined at four concentrations in vivo.
N, Wakiyama, K, Juni, M, Nakano
openaire   +3 more sources

Antiseizure Effects of Cannabidiol in Combination With Cannabigerol in the Maximal Electroshock Seizure Model

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 138, Issue 2, February 2026.
Cannabidiol and cannabigerol suppress maximal electroshock seizures. Cannabidiol and cannabigerol show similar dose–response properties. Both cannabinoids show no toxicity at effective doses. ABSTRACT Current antiseizure therapy for epilepsy is only effective in about 70% of the patient population.
Han Zhong Zhou   +3 more
wiley   +1 more source

The applications of sub-Tenon's anaesthesia for canine ophthalmic surgery : a thesis presented in fulfilment of the requirements for the degree of Master of Veterinary Science (MVSc) at Massey University, Manawatu, New Zealand [PDF]

open access: yes, 2016
Sub-Tenon's anaesthesia is an indispensable anaesthetic technique in human ophthalmic surgery. It produces highly effective regional anaesthesia and has a significantly lower complication rate than the previously used peribulbar and retrobulbar ...
Bayley, Kellam David
core  

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