Results 41 to 50 of about 2,063 (170)

Application of Machine Learning to Discriminate Photoreceptor Cell Species in Xenotransplanted Chimeric Retinas

Clinical and Translational Science, Volume 18, Issue 12, December 2025.
ABSTRACT Photoreceptor transplantation is being studied to restore visual function in retinal diseases causing blindness, including age‐related macular degeneration, hereditary eye diseases, and traumatic retinopathy. Preclinical studies often involve delivering exogenous human photoreceptor cells into animal models' retinas.
Kang V. Li, Annabelle Pan, Ying V. Liu, Bani Antonio‐Aguirre, Joyce Wang, McKaily Adams, Christina McNerney, Sai Bo Bo Tun, Kenneth Jimenez, Yuchen Lu, Zhuolin Li, Minda McNally, Veluchamy A. Barathi, Robert J. Johnston Jr., Mandeep S. Singh   +14 more
wiley   +1 more source

Obtenção de nanocápsulas via polimerização em miniemulsão [PDF]

, 2007
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia QuímicaReações de polimerização em miniemulsão permitem a produção de nanocápsulas com características únicas e de grande ...
Romio, Ana Paula
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Analgesic Effect of Cocaine and Lidocaine/Xylometazoline in Healthy Volunteers Undergoing Awake Nasal Intubation: A Randomized Controlled Crossover Trial

Acta Anaesthesiologica Scandinavica, Volume 69, Issue 6, July 2025.
ABSTRACT Background Several drugs may be used to minimize pain during nasal intubation in awake patients. We hypothesized that the analgesic effect of cocaine would be at least as good (non‐inferior) as that of lidocaine with xylometazoline rated as maximum pain felt during awake nasal intubation of healthy volunteers.
Mo Haslund Larsen, Oscar Rosenkrantz, Rasmus Linnebjerg Knudsen, Rasmus Hesselfeldt, Ole Hilberg, Volkert Siersma, Johan Heiberg, Lars Simon Rasmussen, Dan Isbye   +8 more
wiley   +1 more source

Corneal Cell Matrix‐Conditioned Amniotic Membrane with Improved Biochemical Properties and Corneal Wound Healing Potential: An In Vitro and In Vivo Study

Macromolecular Materials and Engineering, Volume 310, Issue 6, June 2025.
In this research, the amniotic membrane is sought to be enhanced biologically by treating it with primary cultured corneal cells. The findings indicate that amniotic membranes conditioned with limbal stem cells serve as an effective wound dressing that mimics corneal tissue, offering better cell adhesion, and healing properties, paving the way for ...
Zeinab Nokhbedehghan, Zahra Esmaeili, Seyed‐Hashem Daryabari, Hossein Aghamollaei, Sara Simorgh, Jila Majidi, Sanaz Alizadeh, Sadjad Khosravimelal, Narendra Pal Singh Chauhan, Hajar Nasiri, Mazaher Gholipourmalekabadi   +10 more
wiley   +1 more source

Subdermal Laser‐Assisted Scar Subcision (SLASS) Combined With Fractional CO2 Laser for Acne Scars: Efficacy Evaluation

Journal of Cosmetic Dermatology, Volume 24, Issue 5, May 2025.
ABSTRACT Background Rolling atrophic acne scars attach the deeper dermis to the muscular–fascial layer with a fibrous component. Subcision is the most commonly used treatment technique for rolling scars. Aims Our objective is to describe the efficacy and safety profile of a new type of subcision: the “subdermal laser‐assisted scar subcision” (SLASS ...
Adrián Alegre‐Sánchez, Ana Suárez‐Valle, Diego Fernández‐Nieto, Alejandro Lapeña, Elena Macías‐del Toro, Claudia Bernárdez   +5 more
wiley   +1 more source

Pharmacokinetic studies of drug absorption into human skin

, 2010
PhDOptimum therapeutic outcomes require not only proper drug selection but also effective drug delivery and monitoring. The aim of this thesis was to A) study drug delivery through the skin with a liquid formulated to promote absorption, B) develop ...
Al-Otaibi, Faisal Obaid
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Comparison of 3 intranasal mists for anesthetizing maxillary teeth in adults A randomized, double-masked, multicenter phase 3 clinical trial

, 2016
BackgroundThis double-masked, parallel-design, clinical trial assessed whether a combination nasal spray (K305; 3% tetracaine hydrochloride and 0.05% oxymetazoline hydrochloride) compared with a tetracaine-only spray and a placebo spray would be safer ...
Ciancio, Sebastian G., Ayoub, Fadi, Pantera, Eugene A., Sobieraj, Benita D., Marberger, Adam D., Garlapo, Davis A., Pantera, Carole T., Al-Mubarak, Sultan, He, David Y., Myneni, Srinivas R.   +9 more
core   +1 more source

Swimming Exercise Pretreatment Attenuates Postoperative Delirium‐Like Behavior in Type 2 Diabetic Rats by Enhancing Mitochondrial Biogenesis Through Activation of SIRT2 Deacetylation

MedComm, Volume 6, Issue 4, April 2025.
The reduction of SIRT2 following orthopedic surgery in the hippocampus of T2DM rats inhibits the acetylation process of PGC‐1α and the subsequent mitochondrial biogenesis process, leading to mitochondrial dysfunction and postoperative delirium‐like behavior.
Kaixi Liu, Lei Chen, Xinning Mi, Qian Wang, Yitong Li, Jingshu Hong, Xiaoxiao Wang, Yue Li, Yanan Song, Yi Yuan, Jie Wang, Dengyang Han, Taotao Liu, Ning Yang, Xiangyang Guo, Zhengqian Li   +15 more
wiley   +1 more source

UHPLC analysis of degradation products of tetracaine hydrochloride

, 2015
Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of Analytical Chemistry Candidate: Michaela Horáková Supervisor: Ludmila Matysová Title of Diploma Thesis: Determination of Degradation Product of Tetracaine hydrochloride by ...
Horáková, Michaela
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Determination of Tear Break-up Time reference values and ocular tolerance of tetracaine hydrochloride eyedops in healthy horses

, 2010
peer reviewedREASONS FOR PERFORMING STUDY: Tetracaine hydrochloride (THCl) has been reported to cause irritation in dogs. In man, some topical anaesthetics have been shown to disrupt the tear film.
S. J. MONCLIN, Grauwels, Magda, Farnir, Frédéric, F. FARNIR, Monclin, Sébastien, M. GRAUWELS   +5 more
core   +1 more source