Results 31 to 40 of about 2,063 (170)

Murine Biocompatibility Evaluation of an Albumin‐Derived Complex and Nanoparticle Delivery System for Ocular Applications

Journal of Biomedical Materials Research Part A, Volume 114, Issue 3, March 2026.
ABSTRACT Age‐related macular degeneration (AMD) is a leading cause of irreversible vision loss in the aging population, with no curative treatment currently available. Current therapies primarily target late‐stage symptoms and are limited by their frequent and invasive intravitreal (IVT) injections.
Amna Abdalbaqi, Nagaraj Kerur, Matthew P. Ohr, Andre F. Palmer, Katelyn E. Swindle‐Reilly   +4 more
wiley   +1 more source

Anogenital Contact Dermatitis in Spain: A REIDAC Study of Patients Undergoing Patch Testing in 2019–2024

Contact Dermatitis, Volume 94, Issue 3, Page 272-285, March 2026.
Allergic contact dermatitis is very common in patients with anogenital lesions referred for patch testing in Spain. Key allergens include fragrances, preservatives and topical treatments like anaesthetics and steroids. Emerging sensitisers including benzisothiazolinone and sodium metabisulphite are also relevant.
Mercè Grau‐Pérez, Pedro Mercader‐García, Ana María Giménez‐Arnau, Tatiana Sanz‐Sánchez, Violeta Zaragoza Ninet, Susana Córdoba Guijarro, Francisco Javier Miquel Miquel, Juan Francisco Silvestre Salvador, Ricardo González‐Pérez, Inmaculada Ruíz González, Esther Serra Baldrich, José Manuel Carrascosa, Francisco Javier Ortiz de Frutos, Mercedes Rodríguez Serna, María Elena Gatica Ortega, Carmen Paredes Suárez, Francisco José Navarro Triviño, Pablo Chicharro, Marta Andreu, Araceli Sánchez Gilo, José Juan Pereyra Rodríguez, María Antonia Pastor Nieto, Gemma Melé‐Ninot, Paloma Sánchez‐Pedreño Guillén, Enrique Gómez de la Fuente, Marta Elosua‐González, Mónica Munera‐Campos, Fátima Tous Romero, Miguel Ángel Descalzo, Leopoldo Borrego   +29 more
wiley   +1 more source

Tetracaine – selective electrodes with polymer membranes and their application in pharmaceutical formulation control

, 2017
The construction and electrochemical response characteristics of poly(vinyl chloride) (PVC) membrane electrodes for tetracaine hydrochloride (TCH) are described.
Hassan, Ahmed Khudhair, Saad, Bahruddin, Ameen, Suham Towfiq   +2 more
core   +1 more source

Ultrasonographic Ocular Biometry of the Greater Caribbean Manatee (Trichechus manatus manatus)

Veterinary Ophthalmology, Volume 29, Issue 2, March 2026.
ABSTRACT This study aimed to characterize the ocular biometry of the Trichechus manatus manatus applying B‐mode ultrasonography across different age groups. Twenty‐two animals were assessed employing a portable ultrasound device equipped with a linear transducer. Five ocular parameters were assessed: corneal thickness (CT), anterior chamber depth (ACD),
Radan Elvis Matias de Oliveira, Fernanda Loffler Niemeyer Attademo, Rita de Kássia Matias de Oliveira, Romário Parente dos Santos, Fábia de Oliveira Luna, Antonio A. Mignucci‐Giannoni, Lesly J. Cabrias‐Contreras, Fabrício Bezerra de Sá, Flávio José de Lima Silva, Augusto Carlos da Bôaviagem Freire, Moacir Franco de Oliveira   +10 more
wiley   +1 more source

Early sensorimotor restriction in rats induces age‐dependent mitochondrial alterations in skeletal muscles and brain structures

The Journal of Physiology, Volume 604, Issue 6, Page 2512-2524, 15 March 2026.
Abstract figure legend This study aimed to determine whether early sensorimotor restriction (SMR) alters mitochondrial enzyme activities in rat muscles and brain structures. SMR was induced via immobilizing the hind limbs of pups for 16 h per day during the dark phase from birth to postnatal day (PND) 28.
Mélanie Van Gaever, Olivier Dupuy, Erwan Dupont, Marie‐Hélène Canu, Frederic Daussin   +4 more
wiley   +1 more source

MSC‐Derived Exosomal lnc‐AGT‐3: A Novel Anti‐Angiogenic Target in Age‐Related Macular Degeneration Through p53 Signaling Pathway

Aging Cell, Volume 25, Issue 2, February 2026.
MSC‐derived exosomes deliver lnc‐AGT‐3 to vascular endothelial cells, where it binds hnRNP K in the nucleus. This interaction inhibits p53 ubiquitination, enhancing p53 stabilization and transcriptional activation of anti‐angiogenic targets TSP1. Consequently, p53‐mediated signaling is potentiated, effectively suppressing choroidal neovascularization ...
Lingjie Kong, Xiaoyan Han, Siyi Qi, Duo Li, Jingyue Zhang, Linyu Zhang, Shujie Zhang, Qin Jiang, Biao Yan, Chen Zhao   +9 more
wiley   +1 more source

Antiseizure Effects of Cannabidiol in Combination With Cannabigerol in the Maximal Electroshock Seizure Model

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 2, February 2026.
Cannabidiol and cannabigerol suppress maximal electroshock seizures. Cannabidiol and cannabigerol show similar dose–response properties. Both cannabinoids show no toxicity at effective doses. ABSTRACT Current antiseizure therapy for epilepsy is only effective in about 70% of the patient population.
Han Zhong Zhou, Brian Wayne Scott, Yagoda Izabela Oleksak, Willets McIntyre Burnham   +3 more
wiley   +1 more source

Intermittent Fasting Alleviates Anesthesia/Surgery‐Induced Delirium‐Like Behavior in Aged Mice by Remodeling Gut Microbiota

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Preoperative intermittent fasting alleviates postoperative delirium‐like behaviors in aged mice by remodeling gut microbiota and preserving shortchain fatty acids. This gut‐brain interaction maintains hippocampal mitochondrial dynamics and synaptic plasticity, offering a promising non‐pharmacological strategy for perioperative neuroprotection. ABSTRACT
Peiying Huang, Longlu Cao, Tianyu Cao, Xueji Wang, Sichen Cui, Sufang Jiang, Huan Chen, Lichao Di, Sha Li, Lining Huang   +9 more
wiley   +1 more source

Hedgehogs and Angiostrongylus cantonensis: Uncovering the Role of Atelerix albiventris in the Parasite Life Cycle

Integrative Zoology, Volume 21, Issue 1, Page 104-115, January 2026.
ABSTRACT The ongoing invasion of the zoonotic parasite Angiostrongylus cantonensis threatens humans, other mammals, and birds. In Mallorca, neurological disorders associated with this parasite are increasingly reported in free‐living Algerian hedgehogs, Atelerix algirus, raising public health concerns.
Anna Šipková, Kristýna Javorská, Lucia Anettová, Divakaran Pandian, Petr Cibulka, Jana Kačmaříková, Ladislav Novotný, David Modrý   +7 more
wiley   +1 more source

Comparative Analysis Of The Effects Of Topical Anaesthetic Agents On Tear Quantity And Tear Quality

, 2010
This studycompared the effects of different topical anaesthetic agents on tear quantity andtear quality. To establishthis, 30 subjects agedbetween18-35yearswithmeanage 23±2.60years andfree fromocular and systemic diseaseswere used.The study population ...
P Omokhua, George, O, Omokhua, P, O George   +3 more
core   +1 more source