Results 281 to 290 of about 297,906 (337)

On the Stability of Steroids upon Gamma and E-Beam Irradiation and the Protective Effect of Inert Conditions. [PDF]

Molecules
Speleers Q, Meyers A, Rashid H, Dubbelboer Y, Vanneste E, Croonenborghs B, Gillet A, DeMent A, Van Schepdael A, Haghedooren E.   +9 more
europepmc   +1 more source

Molecular detection of pathogens in an equine fever diagnostic panel: 2019–2023

Equine Veterinary Journal, EarlyView.
Abstract Background A common diagnostic approach for febrile horses is to test for a panel of potential pathogens. Panels are curated by expert opinion and vary between diagnostic laboratories. Objectives To report the results of a newly developed equine fever diagnostic panel (EFDP) between 2019 and 2023 and evaluate the frequency of positive results.
Toby L. Pinn‐Woodcock, Melissa S. Aprea, Manigandan Lejeune, Joy E. Tomlinson   +3 more
wiley   +1 more source

The Impact of Tetracycline on the Soil Microbiome and the Rhizosphere of Lettuce (<i>Lactuca sativa</i> L.). [PDF]

Int J Mol Sci
Krupka M, Wolska L, Piechowicz L, Głowacka K, Piotrowicz-Cieślak AI.   +4 more
europepmc   +1 more source

Equine botulism

Equine Veterinary Journal, EarlyView.
Abstract Botulism is a severe and often fatal disease in equine patients worldwide. Clostridium botulinum is a ubiquitous soil organism which produces a potent neurotoxin resulting in neuromuscular blockade and flaccid paralysis in affected animals. Definitive diagnosis is often impractical or impossible, leading to diagnosis and treatment based on ...
Kali Slavik, Robert Whitlock, Amy Johnson   +2 more
wiley   +1 more source

Binding assays enable discovery of Tet(X) inhibitors that combat tetracycline destructase resistance. [PDF]

Chem Sci
Beech MJ, Toma EC, Smith HG, Trush MM, Ang JHJ, Wong MY, Wong CHJ, Ali HS, Butt Z, Goel V, Duarte F, Farley AJM, Walsh TR, Schofield CJ.   +13 more
europepmc   +1 more source

A cellular model of TDP‐43 induces phosphorylated TDP‐43 aggregation with distinct changes in solubility and autophagy dysregulation

The FEBS Journal, EarlyView.
TDP‐43 protein plays a pathological role in sporadic and familial amyotrophic lateral sclerosis (ALS). Here, we developed a cellular model overexpressing TDP‐43 with three mutations linked to familial ALS, termed ‘3X‐TDP‐43’. Mutant 3X‐TDP‐43 expression showed deficits in autophagy flux and colocalization with stress granules.
Matthew B. Dopler, Muhammad I. Abeer, Sanaz Arezoumandan, Keyshawn Cox, Tyler L. Petersen, Esther H. Daniel, Carlton L. Cannon III, Angelica Bautista, Kennedy D. Blancher, Alysia M. Bland, Kylie J. Bond, Dominque A. Davis, Jessica M. Francois, Eliana J. McCray, Justin M. Morgan, Jessica L. Pulliam, Zymir A. Robinson, Mykia J. Taylor, James A. Dowell, Nigel J. Cairns, Michael A. Gitcho   +20 more
wiley   +1 more source

Magneto-Fluorescent Microrobots with Selective Detection Intelligence for High-Energy Explosives and Antibiotics in Aqueous Environments. [PDF]

ACS Appl Mater Interfaces
Senthilnathan N, Oral CM, Pumera M.
europepmc   +1 more source

Zic family member 5 promotes RIO kinase 3 expression to enhance pancreatic cancer survival

The FEBS Journal, EarlyView.
This study demonstrates that targeting ZIC5 increases gemcitabine sensitivity and induces pancreatic cancer shrinkage in vivo. The findings also show that ALDH3B1, PTGES, and TUFT1, the downstream genes of ZIC5, contribute to gemcitabine resistance in pancreatic cancer cells.
Reiko Satow, Yuki Kashiwaba, Misaki Okao, Shin Takano, Yuna Aiga, Atsuko Yoneda, Kazuyoshi Hosomichi, Kiyoko Fukami   +7 more
wiley   +1 more source

Extreme multivalency and a composite short linear motif facilitate PCNA‐binding, localisation and abundance of p21 (CDKN1A)

The FEBS Journal, EarlyView.
Regions flanking the PCNA‐binding motif in p21 contribute to high‐affinity binding through complementary charges without specific contacts. These regions affect p21 abundance, but their exact Lys/Arg composition is unimportant for PCNA binding. Conversely, both context and Lys/Arg composition of the N‐terminal flanking region are crucial for p21 ...
Signe Simonsen, Fia B. Larsen, Caroline K. Søgaard, Nicolas Jonsson, Kresten Lindorff‐Larsen, Per Bruheim, Marit Otterlei, Rasmus Hartmann‐Petersen, Birthe B. Kragelund   +8 more
wiley   +1 more source

Efficient Removal of Tetracyclines and Their Metabolites from Wastewater Using Purified Stevensite: Adsorption Capacity, Reusability, and Antibiotic Decontamination. [PDF]

Antibiotics (Basel)
García-Criado N, Martín-Pozo L, Martín J, Santos JL, Aparicio I, Alonso E.   +5 more
europepmc   +1 more source